دورية أكاديمية
Improving the reproducibility of motor unit number index.
| العنوان: | Improving the reproducibility of motor unit number index. |
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| المؤلفون: | Escorcio-Bezerra ML; Department of Neurology, Universidade Federal de São Paulo, SP, Brazil., Oliveira ASB; Department of Neurology, Universidade Federal de São Paulo, SP, Brazil., De Oliveira Braga NI; Department of Neurology, Universidade Federal de São Paulo, SP, Brazil., Manzano GM; Department of Neurology, Universidade Federal de São Paulo, SP, Brazil. |
| المصدر: | Muscle & nerve [Muscle Nerve] 2017 May; Vol. 55 (5), pp. 635-638. Date of Electronic Publication: 2017 Feb 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 7803146 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4598 (Electronic) Linking ISSN: 0148639X NLM ISO Abbreviation: Muscle Nerve Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005-> : Hoboken, NJ : John Wiley & Sons Original Publication: New York, NY : John Wiley & Sons |
| مواضيع طبية MeSH: | Action Potentials/*physiology , Motor Neurons/*physiology , Muscle, Skeletal/*physiology, Adult ; Aged ; Amyotrophic Lateral Sclerosis/physiopathology ; Disease Progression ; Electromyography/methods ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Recruitment, Neurophysiological/physiology ; Reproducibility of Results |
| مستخلص: | Introduction: Reproducibility is an important aspect of any method intended to be a marker of disease progression. In this study we investigated approaches for improving motor unit number index (MUNIX) reproducibility. Methods: We used the intraclass correlation coefficient (ICC) and the coefficient of variation (CV) to study reproducibility in healthy subjects. We tested reproducibility between test and retest of a single MUNIX from 3 different muscles (S-MUNIX) and also of the mean of a set of 3 measurements from these same muscles (M-MUNIX). Results: M-MUNIX was more reproducible than S-MUNIX. The CV showed a greater improvement than the ICC in all 3 muscles. Conclusions: M-MUNIX may be a valuable approach for following motor unit loss, because it is more replicable than MUNIX. This may be especially relevant in amyotrophic lateral sclerosis patients, in whom MUNIX variability is higher than in healthy individuals. Muscle Nerve, 2016 Muscle Nerve 55: 635-638, 2017. (© 2016 Wiley Periodicals, Inc.) |
| فهرسة مساهمة: | Keywords: ALS; MUNIX; coefficient of variation; intraclass correlation coefficient; motor unit; reproducibility |
| تواريخ الأحداث: | Date Created: 20160721 Date Completed: 20170428 Latest Revision: 20180724 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/mus.25260 |
| PMID: | 27438087 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1097-4598 |
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| DOI: | 10.1002/mus.25260 |