دورية أكاديمية
Chemical, microscopic, and microbiological analysis of a functionalized poly-ether-ether-ketone-embedding antibiofilm compounds.
| العنوان: | Chemical, microscopic, and microbiological analysis of a functionalized poly-ether-ether-ketone-embedding antibiofilm compounds. |
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| المؤلفون: | Montero JF; Center for Research on Dental Implants (CEPID), School of Dentistry (ODT), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil., Barbosa LC; Department of Chemistry, Federal University of Minas Gerais (UFMG), Av. Pres. Antônio Carlos, 6627, Campus Pampulha, CEP 31270-901, Belo Horizonte, MG, Brazil.; Department of Chemistry, Federal University of Viçosa, Viçosa/MG 36570-000, Brazil., Pereira UA; Department of Chemistry, Federal University of Viçosa, Viçosa/MG 36570-000, Brazil., Barra GM; Department of Mechanical Engineering (EMC), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil., Fredel MC; Department of Mechanical Engineering (EMC), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil., Benfatti CA; Center for Research on Dental Implants (CEPID), School of Dentistry (ODT), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil., Magini RS; Center for Research on Dental Implants (CEPID), School of Dentistry (ODT), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil., Pimenta AL; Department of Biologie, Université De Cergy Pontoise, 2, Av. Adolphe Chauvin, Cergy Pontoise, 95302, France., Souza JC; Center for Research on Dental Implants (CEPID), School of Dentistry (ODT), Federal University of Santa Catarina (UFSC), Florianópolis/SC, 88040-900, Brazil. ricardo.magini@gmail.com.; Center for Microelectromechanical Systems (CMEMS), Department of Mechanical Engineering (DEM), Guimarães, 4800-058, Portugal. ricardo.magini@gmail.com. |
| المصدر: | Journal of biomedical materials research. Part A [J Biomed Mater Res A] 2016 Dec; Vol. 104 (12), pp. 3015-3020. Date of Electronic Publication: 2016 Aug 05. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101234237 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4965 (Electronic) Linking ISSN: 15493296 NLM ISO Abbreviation: J Biomed Mater Res A Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hoboken, NJ : John Wiley & Sons, c2002- |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*pharmacology , Biocompatible Materials/*pharmacology , Biofilms/*drug effects , Ketones/*pharmacology , Lactams/*pharmacology , Polyethylene Glycols/*pharmacology , Streptococcus mutans/*drug effects, Anti-Bacterial Agents/chemistry ; Benzophenones ; Biocompatible Materials/chemistry ; Humans ; Ketones/chemistry ; Lactams/chemistry ; Polyethylene Glycols/chemistry ; Polymers ; Streptococcus mutans/growth & development ; Streptococcus mutans/physiology ; Surface Properties |
| مستخلص: | Poly-ether-ether-ketone (PEEK) is currently introduced as an alternative material for orthopedic implants due to its biocompatibility and low elastic modulus compared to titanium. Also, a sulphonation treatment can functionalize PEEK to embed therapeutical substances. The objective of this work was to functionalize a PEEK film to incorporate novel lactam-based antibiofilms compounds. PEEK samples were functionalized by sulphuric acid treatment and then dissolved in dimethylsulfoxide, where lactams were added to be incorporated into the polymer. A dip-coating technique was used to synthesize a thin film on a glass-based substrate. The degree of sulfonation (DS) and the incorporation of lactams into sulphonated PEEK (sPEEK) were analyzed by Fourier transform infrared spectroscopy, nuclear magnetic resonance, thermogravimetric analysis (TGA), and scanning electron microscopy. A DS of 65% was obtained and TGA curves confirmed the presence of SO (© 2016 Wiley Periodicals, Inc.) |
| فهرسة مساهمة: | Keywords: PEEK; Streptococcus mutans; biofilm; biofilm inhibition; lactam; rubrolide derivatives; sPEEK |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) 0 (Benzophenones) 0 (Biocompatible Materials) 0 (Ketones) 0 (Lactams) 0 (Polymers) 31694-16-3 (polyetheretherketone) 3WJQ0SDW1A (Polyethylene Glycols) |
| تواريخ الأحداث: | Date Created: 20160727 Date Completed: 20171106 Latest Revision: 20211204 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/jbm.a.35842 |
| PMID: | 27458927 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1552-4965 |
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| DOI: | 10.1002/jbm.a.35842 |