دورية أكاديمية
Assessing the Dengue Diagnosis Capability Gap in the Military Health System.
| العنوان: | Assessing the Dengue Diagnosis Capability Gap in the Military Health System. |
|---|---|
| المؤلفون: | Pal S; Viral and Rickettsial Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910., Jasper LE; U.S. Army Medical Materiel Development Activity, 1430 Veterans Drive, Frederick, MD 21702., Lawrence KL; U.S. Army Medical Materiel Development Activity, 1430 Veterans Drive, Frederick, MD 21702., Walter M; U.S. Army Medical Materiel Development Activity, 1430 Veterans Drive, Frederick, MD 21702., Gilliland T Jr; Viral and Rickettsial Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910., Dauner AL; Viral and Rickettsial Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910., Palys TJ; Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910., Wu SJ; Viral and Rickettsial Diseases Department, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910. |
| المصدر: | Military medicine [Mil Med] 2016 Aug; Vol. 181 (8), pp. 756-66. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 2984771R Publication Model: Print Cited Medium: Internet ISSN: 1930-613X (Electronic) Linking ISSN: 00264075 NLM ISO Abbreviation: Mil Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Oxford : Oxford University Press Original Publication: Washington, D.C. : Association of Military Surgeons, United States, 1955- |
| مواضيع طبية MeSH: | Sensitivity and Specificity*, Dengue/*diagnosis , Diagnostic Tests, Routine/*standards, Antigen-Antibody Reactions ; Dengue Virus ; Diagnostic Tests, Routine/methods ; Enzyme-Linked Immunosorbent Assay/methods ; Humans ; Military Medicine/methods ; Military Medicine/standards ; Public Health/methods ; Surveys and Questionnaires ; Time Factors ; Workforce |
| مستخلص: | Dengue, one of the most widespread infectious diseases, has affected U.S. military readiness throughout history. We explored the dengue diagnosis capability gap by circulating a questionnaire among military end users to determine in what capacity diagnostic test results are needed and how these results would be used at various roles of care in the Military Health System. Results were used to generate target product profiles for potential diagnostic tests. We determined that at far-forward locations, diagnostic tests need to be rugged and easy to use and are primarily needed to inform medical evacuation decisions. In mobile or fixed hospitals, diagnostics can be less portable but must be accurate enough to inform patient care decisions reliably. We then evaluated the suitability of using rapid diagnostic tests and enzyme-linked immunosorbent assays based on published performance characteristics, and we used a model to determine positive and negative predictive values in certain simulated deployments. In far-forward settings, a rapid diagnostic test comprising both antigen- and antibody-based detection can fulfill the capability gap with reasonable accuracy, whereas at higher roles of care immunoglobulin M-enzyme-linked immunosorbent assay was determined to be the most suitable option. (Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.) |
| تواريخ الأحداث: | Date Created: 20160803 Date Completed: 20180109 Latest Revision: 20181202 |
| رمز التحديث: | 20231215 |
| DOI: | 10.7205/MILMED-D-15-00231 |
| PMID: | 27483511 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1930-613X |
|---|---|
| DOI: | 10.7205/MILMED-D-15-00231 |