دورية أكاديمية
The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis.
العنوان: | The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis. |
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المؤلفون: | Steenackers W; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Cesarino I; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Klíma P; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Quareshy M; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Vanholme R; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Corneillie S; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Kumpf RP; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Van de Wouwer D; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Ljung K; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Goeminne G; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Novák O; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Zažímalová E; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Napier R; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.)., Boerjan W; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.) bartel.vanholme@psb.vib-ugent.be wout.boerjan@psb.vib-ugent.be., Vanholme B; Department of Plant Systems Biology, VIB, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Gent, Belgium (W.S., I.C., R.V., S.C., R.P.K., D.V.d.W., G.G., W.B., B.V.);Department of Botany, Institute of Biosciences, University of São Paulo, 05508-090 Butantã, São Paulo, Brazil (I.C.);Institute of Experimental Botany, the Czech Academy of Sciences, 16502 Prague, the Czech Republic (P.K., E.Z.);School of Life Sciences, University of Warwick, CV4 7AL Coventry, United Kingdom (M.Q., R.N.);Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden (K.L., O.N.); andLaboratory of Growth Regulators, Centre of the Region Haná for Biotechnological and Agricultural Research, Institute of Experimental Botany CAS and Faculty of Science of Palacký University, Šlechtitelů 27, CZ-78371 Olomouc, Czech Republic (O.N.) bartel.vanholme@psb.vib-ugent.be wout.boerjan@psb.vib-ugent.be. |
المصدر: | Plant physiology [Plant Physiol] 2016 Oct; Vol. 172 (2), pp. 874-888. Date of Electronic Publication: 2016 Aug 09. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: American Society of Plant Biologists Country of Publication: United States NLM ID: 0401224 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2548 (Electronic) Linking ISSN: 00320889 NLM ISO Abbreviation: Plant Physiol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: Original Publication: Lancaster, Pa., American Society of Plant Physiologists. |
مواضيع طبية MeSH: | Cinnamates/*pharmacology , Homeostasis/*drug effects , Indoleacetic Acids/*metabolism , Lignin/*biosynthesis , Phenylpropionates/*pharmacology, Arabidopsis/drug effects ; Arabidopsis/genetics ; Arabidopsis/metabolism ; Benzoates/metabolism ; Benzoates/pharmacology ; Biosynthetic Pathways/drug effects ; Cinnamates/chemistry ; Cinnamates/metabolism ; Coenzyme A Ligases/antagonists & inhibitors ; Coenzyme A Ligases/metabolism ; Dose-Response Relationship, Drug ; Mass Spectrometry ; Microscopy, Confocal ; Phenylpropionates/chemistry ; Phenylpropionates/metabolism ; Plant Roots/drug effects ; Plant Roots/genetics ; Plant Roots/metabolism ; Plants, Genetically Modified ; Seedlings/drug effects ; Seedlings/genetics ; Seedlings/growth & development ; Seedlings/metabolism ; Trans-Cinnamate 4-Monooxygenase/antagonists & inhibitors ; Trans-Cinnamate 4-Monooxygenase/metabolism |
مستخلص: | The phenylpropanoid 3,4-(methylenedioxy)cinnamic acid (MDCA) is a plant-derived compound first extracted from roots of Asparagus officinalis and further characterized as an allelochemical. Later on, MDCA was identified as an efficient inhibitor of 4-COUMARATE-CoA LIGASE (4CL), a key enzyme of the general phenylpropanoid pathway. By blocking 4CL, MDCA affects the biosynthesis of many important metabolites, which might explain its phytotoxicity. To decipher the molecular basis of the allelochemical activity of MDCA, we evaluated the effect of this compound on Arabidopsis thaliana seedlings. Metabolic profiling revealed that MDCA is converted in planta into piperonylic acid (PA), an inhibitor of CINNAMATE-4-HYDROXYLASE (C4H), the enzyme directly upstream of 4CL. The inhibition of C4H was also reflected in the phenolic profile of MDCA-treated plants. Treatment of in vitro grown plants resulted in an inhibition of primary root growth and a proliferation of lateral and adventitious roots. These observed growth defects were not the consequence of lignin perturbation, but rather the result of disturbing auxin homeostasis. Based on DII-VENUS quantification and direct measurement of cellular auxin transport, we concluded that MDCA disturbs auxin gradients by interfering with auxin efflux. In addition, mass spectrometry was used to show that MDCA triggers auxin biosynthesis, conjugation, and catabolism. A similar shift in auxin homeostasis was found in the c4h mutant ref3-2, indicating that MDCA triggers a cross talk between the phenylpropanoid and auxin biosynthetic pathways independent from the observed auxin efflux inhibition. Altogether, our data provide, to our knowledge, a novel molecular explanation for the phytotoxic properties of MDCA. (© 2016 American Society of Plant Biologists. All Rights Reserved.) |
References: | Genes Dev. 1999 Jul 1;13(13):1678-91. (PMID: 10398681) Plant J. 1999 Nov;20(4):503-8. (PMID: 10607302) Plant Physiol. 2001 Jun;126(2):524-35. (PMID: 11402184) Plant J. 2002 Jan;29(2):153-68. (PMID: 11862947) Plant Physiol. 2003 Jan;131(1):254-63. (PMID: 12529533) Annu Rev Plant Biol. 2003;54:519-46. (PMID: 14503002) Nature. 2003 Nov 13;426(6963):147-53. (PMID: 14614497) Development. 2004 Feb;131(3):657-68. (PMID: 14711878) Plant Cell. 2004 May;16(5):1191-205. (PMID: 15100399) Curr Opin Plant Biol. 2004 Aug;7(4):472-9. (PMID: 15231272) Nat Rev Mol Cell Biol. 2004 Sep;5(9):763-9. (PMID: 15340383) Dev Cell. 2005 Jul;9(1):109-19. (PMID: 15992545) Science. 2006 May 12;312(5775):914-8. (PMID: 16601150) Plant Physiol. 1992 May;99(1):256-62. (PMID: 16668858) Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10116-21. (PMID: 16785429) Plant Cell. 2007 Jan;19(1):118-30. (PMID: 17259263) Nature. 2007 Apr 5;446(7136):640-5. (PMID: 17410169) Arch Biochem Biophys. 2007 Aug 15;464(2):155-68. (PMID: 17470359) Arch Biochem. 1949 Jan;20(1):131-6. (PMID: 18104404) Trends Plant Sci. 2007 Dec;12(12):556-63. (PMID: 18198522) J Plant Physiol. 2009 Jan 1;166(1):63-71. (PMID: 18448193) Plant Biol (Stuttg). 2008 Nov;10(6):725-31. (PMID: 18950430) J Exp Bot. 2009;60(3):751-63. (PMID: 19129166) Plant J. 2009 Dec;60(5):771-82. (PMID: 19682296) Pest Manag Sci. 2010 Feb;66(2):113-20. (PMID: 19823992) Genes Dev. 1991 Mar;5(3):438-46. (PMID: 2001843) Mol Plant. 2010 Jan;3(1):2-20. (PMID: 20035037) Plant Cell. 2010 May;22(5):1620-32. (PMID: 20511296) Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a001537. (PMID: 20516130) Plant Physiol. 2010 Oct;154(2):874-86. (PMID: 20729393) J Plant Physiol. 2011 Jul 15;168(11):1149-56. (PMID: 21511360) PLoS Comput Biol. 2011 May;7(5):e1002047. (PMID: 21625579) Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20814-9. (PMID: 22123972) Nature. 2012 Jan 15;482(7383):103-6. (PMID: 22246322) Annu Rev Plant Biol. 2012;63:563-90. (PMID: 22404466) J Exp Bot. 2012 Jun;63(10):3815-27. (PMID: 22438304) Nat Chem Biol. 2012 Apr 01;8(5):477-85. (PMID: 22466420) Planta. 2012 Aug;236(2):597-612. (PMID: 22476291) Proc Natl Acad Sci U S A. 2012 Jun 19;109(25):10101-6. (PMID: 22665765) Plant Mol Biol. 2012 Aug;79(6):569-81. (PMID: 22684430) Plant J. 2012 Nov;72(3):523-36. (PMID: 22725617) Plant Cell. 2012 Sep;24(9):3506-29. (PMID: 23012438) Curr Opin Biotechnol. 2013 Apr;24(2):336-43. (PMID: 23228388) Expert Rev Clin Pharmacol. 2013 Jan;6(1):41-7. (PMID: 23272792) Science. 2013 Nov 15;342(6160):860-3. (PMID: 24158907) New Phytol. 2014 Jan;201(2):466-75. (PMID: 24251900) J Chem Ecol. 1990 May;16(5):1707-18. (PMID: 24263839) ACS Chem Biol. 2014 Mar 21;9(3):673-82. (PMID: 24313839) J Exp Bot. 2014 Jun;65(10):2633-43. (PMID: 24474807) J Plant Physiol. 2014 Mar 15;171(6):429-37. (PMID: 24594395) Trends Cell Biol. 2014 Aug;24(8):443-8. (PMID: 24704103) J Chem Ecol. 2014 Jun;40(6):515-6. (PMID: 24946747) Ann Bot. 2015 Jun;115(7):1053-74. (PMID: 25878140) J Biol Chem. 2016 Mar 4;291(10):5385-95. (PMID: 26742840) Plant Physiol. 2016 Sep;172(1):198-220. (PMID: 27485881) Planta. 1996 Apr;198(4):532-541. (PMID: 28321663) Development. 1993 Sep;119(1):71-84. (PMID: 8275865) Cell. 1996 Jan 12;84(1):61-71. (PMID: 8548827) Plant J. 1996 Sep;10(3):403-13. (PMID: 8811856) Plant Physiol. 1997 Mar;113(3):729-38. (PMID: 9085570) Arch Biochem Biophys. 1977 Nov;184(1):237-48. (PMID: 921295) Plant Cell. 1997 Nov;9(11):1963-71. (PMID: 9401121) Plant Physiol. 1998 Sep;118(1):209-18. (PMID: 9733540) |
معلومات مُعتمدة: | BB/L009366 United Kingdom Biotechnology and Biological Sciences Research Council |
المشرفين على المادة: | 0 (Benzoates) 0 (Cinnamates) 0 (Indoleacetic Acids) 0 (Phenylpropionates) 0 (phenylpropanoid 3,4-(methylenedioxy)cinnamic acid) 140-10-3 (cinnamic acid) 9005-53-2 (Lignin) EC 1.14.14.91 (Trans-Cinnamate 4-Monooxygenase) EC 6.2.1.- (Coenzyme A Ligases) EC 6.2.1.12 (4-coumarate-CoA ligase) QX3V1NO0KH (piperonylic acid) |
تواريخ الأحداث: | Date Created: 20160811 Date Completed: 20171010 Latest Revision: 20210224 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC5047068 |
DOI: | 10.1104/pp.15.01972 |
PMID: | 27506238 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1532-2548 |
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DOI: | 10.1104/pp.15.01972 |