دورية أكاديمية
Tissue-specific contribution of macrophages to wound healing.
| العنوان: | Tissue-specific contribution of macrophages to wound healing. |
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| المؤلفون: | Minutti CM; Centre for Immunity, Infection and Evolution, and the Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom., Knipper JA; Centre for Immunity, Infection and Evolution, and the Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom., Allen JE; School of Biological Sciences, Faculty of Biology, Medicine & Health & Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester M13 9PT, United Kingdom. Electronic address: judi.allen@manchester.ac.uk., Zaiss DM; Centre for Immunity, Infection and Evolution, and the Institute for Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3FL, United Kingdom. Electronic address: Dietmar.Zaiss@ed.ac.uk. |
| المصدر: | Seminars in cell & developmental biology [Semin Cell Dev Biol] 2017 Jan; Vol. 61, pp. 3-11. Date of Electronic Publication: 2016 Aug 10. |
| نوع المنشور: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: England NLM ID: 9607332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-3634 (Electronic) Linking ISSN: 10849521 NLM ISO Abbreviation: Semin Cell Dev Biol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Academic Press Original Publication: London, UK : Academic Press, c1996- |
| مواضيع طبية MeSH: | Organ Specificity* , Wound Healing*, Macrophages/*pathology, Animals ; Humans ; Inflammation/pathology ; Lung/pathology ; Signal Transduction |
| مستخلص: | Macrophages are present in all tissues, either as resident cells or monocyte-derived cells that infiltrate into tissues. The tissue site largely determines the phenotype of tissue-resident cells, which help to maintain tissue homeostasis and act as sentinels of injury. Both tissue resident and recruited macrophages make a substantial contribution to wound healing following injury. In this review, we evaluate how macrophages in two fundamentally distinct tissues, i.e. the lung and the skin, differentially contribute to the process of wound healing. We highlight the commonalities of macrophage functions during repair and contrast them with distinct, tissue-specific functions that macrophages fulfill during the different stages of wound healing. (Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.) |
| معلومات مُعتمدة: | MR/K01207X/2 United Kingdom MRC_ Medical Research Council; MR/M011755/1 United Kingdom MRC_ Medical Research Council; MR/K01207X/1 United Kingdom MRC_ Medical Research Council; 106898/A/15/Z United Kingdom WT_ Wellcome Trust |
| فهرسة مساهمة: | Keywords: Extra-cellular matrix; Inflammation; Lung; Macrophage; Skin; Tissue repair |
| تواريخ الأحداث: | Date Created: 20160814 Date Completed: 20171225 Latest Revision: 20210109 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1016/j.semcdb.2016.08.006 |
| PMID: | 27521521 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1096-3634 |
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| DOI: | 10.1016/j.semcdb.2016.08.006 |