التفاصيل البيبلوغرافية
| العنوان: |
Molecular Dynamics of Photosystem II Embedded in the Thylakoid Membrane. |
| المؤلفون: |
van Eerden FJ; Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 7, 9747 AG, Groningen, The Netherlands., van den Berg T; Department of Physics and Astronomy, Faculteit der Exacte Wetenschappen, Vrije Universiteit , De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands., Frederix PWJM; Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 7, 9747 AG, Groningen, The Netherlands., de Jong DH; Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 7, 9747 AG, Groningen, The Netherlands., Periole X; Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 7, 9747 AG, Groningen, The Netherlands., Marrink SJ; Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen , Nijenborgh 7, 9747 AG, Groningen, The Netherlands. |
| المصدر: |
The journal of physical chemistry. B [J Phys Chem B] 2017 Apr 20; Vol. 121 (15), pp. 3237-3249. Date of Electronic Publication: 2016 Sep 28. |
| نوع المنشور: |
Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: American Chemical Society Country of Publication: United States NLM ID: 101157530 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5207 (Electronic) Linking ISSN: 15205207 NLM ISO Abbreviation: J Phys Chem B Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Washington, D.C. : American Chemical Society, c1997- |
| مواضيع طبية MeSH: |
Molecular Dynamics Simulation*, Photosystem II Protein Complex/*chemistry , Thylakoids/*chemistry, Energy Transfer ; Photosystem II Protein Complex/metabolism ; Thylakoids/metabolism |
| مستخلص: |
Photosystem II (PSII) is one of the key protein complexes in photosynthesis. We introduce a coarse grained model of PSII and present the analysis of 60 μs molecular dynamics simulations of PSII in both monomeric and dimeric form, embedded in a thylakoid membrane model that reflects its native lipid composition. We describe in detail the setup of the protein complex and the many natural cofactors and characterize their mobility. Overall we find that the protein subunits and cofactors are more flexible toward the periphery of the complex as well as near the PLQ exchange cavity and at the dimer interface. Of all cofactors, β-carotenes show the highest mobility. Some of the β-carotenes diffuse in and out of the protein complex via the thylakoid membrane. In contrast with the PSII dimer, the monomeric form adopts a tilted conformation in the membrane, with strong interactions between the soluble PsbO subunit and the glycolipid headgroups. Interestingly, the tilted conformation causes buckling of the membrane. Together, our results provide an unprecedented view of PSII dynamics on a microsecond time scale. Our data may be used as basis for the interpretation of experimental data as well as for theoretical models describing exciton energy transfer. |
| المشرفين على المادة: |
0 (Photosystem II Protein Complex) |
| تواريخ الأحداث: |
Date Created: 20160915 Date Completed: 20180507 Latest Revision: 20180507 |
| رمز التحديث: |
20221213 |
| DOI: |
10.1021/acs.jpcb.6b06865 |
| PMID: |
27624992 |
| قاعدة البيانات: |
MEDLINE |
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