دورية أكاديمية
Direct and label-free detection of the human growth hormone in urine by an ultrasensitive bimodal waveguide biosensor.
| العنوان: | Direct and label-free detection of the human growth hormone in urine by an ultrasensitive bimodal waveguide biosensor. |
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| المؤلفون: | González-Guerrero AB; Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain., Maldonado J; Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain., Dante S; Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain., Grajales D; Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain., Lechuga LM; Nanobiosensors and Bioanalytical Applications Group, Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, CIBER-BBN and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193, Barcelona, Spain. |
| المصدر: | Journal of biophotonics [J Biophotonics] 2017 Jan; Vol. 10 (1), pp. 61-67. Date of Electronic Publication: 2016 Sep 27. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101318567 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1864-0648 (Electronic) Linking ISSN: 1864063X NLM ISO Abbreviation: J Biophotonics Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Weinheim : Wiley-VCH |
| مواضيع طبية MeSH: | Biosensing Techniques*, Human Growth Hormone/*urine, Humans ; Interferometry ; Limit of Detection |
| مستخلص: | A label-free interferometric transducer showing a theoretical detection limit for homogeneous sensing of 5 × 10 -8 RIU, being equivalent to a protein mass coverage resolution of 2.8 fg mm -2 , is used to develop a high sensitive biosensor for protein detection. The extreme sensitivity of this transducer combined with a selective bioreceptor layer enables the direct evaluation of the human growth hormone (hGH) in undiluted urine matrix in the 10 pg mL -1 range. (© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.) |
| فهرسة مساهمة: | Keywords: BiMW interferometer; hGH detection; label-free biosensing; pg/mL detection range; silicon nanowaveguides |
| المشرفين على المادة: | 12629-01-5 (Human Growth Hormone) |
| تواريخ الأحداث: | Date Created: 20160928 Date Completed: 20180105 Latest Revision: 20220317 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/jbio.201600154 |
| PMID: | 27669684 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1864-0648 |
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| DOI: | 10.1002/jbio.201600154 |