دورية أكاديمية

Macropinocytosis Exploitation by Cancers and Cancer Therapeutics.

التفاصيل البيبلوغرافية
العنوان: Macropinocytosis Exploitation by Cancers and Cancer Therapeutics.
المؤلفون: Ha KD; Department of Anesthesia, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco San Francisco, CA, USA., Bidlingmaier SM; Department of Anesthesia, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco San Francisco, CA, USA., Liu B; Department of Anesthesia, UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco San Francisco, CA, USA.
المصدر: Frontiers in physiology [Front Physiol] 2016 Sep 12; Vol. 7, pp. 381. Date of Electronic Publication: 2016 Sep 12 (Print Publication: 2016).
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne : Frontiers Research Foundation
مستخلص: Macropinocytosis has long been known as a primary method for cellular intake of fluid-phase and membrane-bound bulk cargo. This review seeks to re-examine the latest studies to emphasize how cancers exploit macropinocytosis to further their tumorigenesis, including details in how macropinocytosis can be adapted to serve diverse functions. Furthermore, this review will also cover the latest endeavors in targeting macropinocytosis as an avenue for novel therapeutics.
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معلومات مُعتمدة: R01 CA118919 United States CA NCI NIH HHS; R01 CA129491 United States CA NCI NIH HHS; R01 CA171315 United States CA NCI NIH HHS
فهرسة مساهمة: Keywords: altered membrane dynamics; macropinocytosis; macropinosome; neurodegenerative disease; pathogen entry; receptor-dependent macropinocytosis; targeted cancer therapy; tumor selective internalization
تواريخ الأحداث: Date Created: 20160928 Date Completed: 20160927 Latest Revision: 20220409
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC5018483
DOI: 10.3389/fphys.2016.00381
PMID: 27672367
قاعدة البيانات: MEDLINE
الوصف
تدمد:1664-042X
DOI:10.3389/fphys.2016.00381