دورية أكاديمية
Predictions Shape Confidence in Right Inferior Frontal Gyrus.
| العنوان: | Predictions Shape Confidence in Right Inferior Frontal Gyrus. |
|---|---|
| المؤلفون: | Sherman MT; Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9QJ, United Kingdom, School of Psychology, University of Sussex, Falmer BN1 9QH, United Kingdom, maxinesherman@gmail.com., Seth AK; Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9QJ, United Kingdom, Department of Informatics, University of Sussex, Falmer BN1 9QJ, United Kingdom., Kanai R; Sackler Centre for Consciousness Science, University of Sussex, Brighton BN1 9QJ, United Kingdom, School of Psychology, University of Sussex, Falmer BN1 9QH, United Kingdom, Department of Neuroinformatics, Araya Brain Imaging, Tokyo 102-0093, Japan, and YHouse Inc., New York, New York 10023. |
| المصدر: | The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2016 Oct 05; Vol. 36 (40), pp. 10323-10336. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Washington, DC : Society for Neuroscience Original Publication: [Baltimore, Md.] : The Society, c1981- |
| مواضيع طبية MeSH: | Form Perception/*physiology , Frontal Lobe/*physiology, Adult ; Attention/physiology ; Brain Mapping ; Decision Making/physiology ; Female ; Frontal Lobe/anatomy & histology ; Humans ; Magnetic Resonance Imaging ; Male ; Neural Pathways/anatomy & histology ; Neural Pathways/physiology ; Occipital Lobe/anatomy & histology ; Occipital Lobe/physiology ; Oxygen/blood ; Visual Cortex/anatomy & histology ; Visual Cortex/physiology ; White Matter/anatomy & histology ; White Matter/physiology ; Young Adult |
| مستخلص: | It is clear that prior expectations shape perceptual decision-making, yet their contribution to the construction of subjective decision confidence remains largely unexplored. We recorded fMRI data while participants made perceptual decisions and confidence judgments, manipulating perceptual prior expectations while controlling for potential confounds of attention. Results show that subjective confidence increases as expectations increasingly support the decision, and that this relationship is associated with BOLD activity in right inferior frontal gyrus (rIFG). Specifically, rIFG is sensitive to the discrepancy between expectation and decision (mismatch), and higher mismatch responses are associated with lower decision confidence. Connectivity analyses revealed expectancy information to be represented in bilateral orbitofrontal cortex and sensory signals to be represented in intracalcarine sulcus. Together, our results indicate that predictive information is integrated into subjective confidence in rIFG, and reveal an occipital-frontal network that constructs confidence from top-down and bottom-up signals. This interpretation was further supported by exploratory findings that the white matter density of right orbitofrontal cortex negatively predicted its respective contribution to the construction of confidence. Our findings advance our understanding of the neural basis of subjective perceptual processes by revealing an occipitofrontal functional network that integrates prior beliefs into the construction of confidence. Significance Statement: Perceptual decision-making is typically conceived as an integration of bottom-up and top-down influences. However, perceptual decisions are accompanied by a sense of confidence. Confidence is an important facet of perceptual consciousness yet remains poorly understood. Here we implicate right inferior frontal gyrus in constructing confidence from the discrepancy between perceptual judgment and its prior probability. Furthermore, we place right inferior frontal gyrus within an occipitofrontal network, consisting of orbitofrontal cortex and intracalcarine sulcus, which represents and communicates relevant top-down and bottom-up signals. Together, our data reveal a role of frontal regions in the top-down processes enabling perceptual decisions to become available for conscious report. (Copyright © 2016 the authors 0270-6474/16/3610323-14$15.00/0.) |
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| فهرسة مساهمة: | Keywords: confidence; expectation; fMRI; inferior frontal gyrus; perception; prediction error |
| المشرفين على المادة: | S88TT14065 (Oxygen) |
| تواريخ الأحداث: | Date Created: 20161007 Date Completed: 20170724 Latest Revision: 20200225 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC6705584 |
| DOI: | 10.1523/JNEUROSCI.1092-16.2016 |
| PMID: | 27707969 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1529-2401 |
|---|---|
| DOI: | 10.1523/JNEUROSCI.1092-16.2016 |