دورية أكاديمية
أعرض في EDS

Surgical treatment of childhood hepatoblastoma in the Netherlands (1990-2013).

التفاصيل البيبلوغرافية
العنوان: Surgical treatment of childhood hepatoblastoma in the Netherlands (1990-2013).
المؤلفون: Busweiler LA; Pediatric Surgical Center of Amsterdam, Emma Children's Hospital-Academic Medical Center and VU Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands. l.a.d.busweiler@lumc.nl., Wijnen MH; Pediatric Surgical Center of Amsterdam, Emma Children's Hospital-Academic Medical Center and VU Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.; Department of Pediatric Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., Wilde JC; Pediatric Surgical Center of Amsterdam, Emma Children's Hospital-Academic Medical Center and VU Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.; Department of Pediatric Surgery, University Hospital, Geneva, Switzerland., Sieders E; Department of Surgery, University Medical Center Groningen, Groningen, The Netherlands., Terwisscha van Scheltinga SE; Department of Pediatric Surgery, Sophia Children's Hospital-Erasmus Medical Center, Rotterdam, The Netherlands., van Heurn LW; Department of Pediatric Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., Ziros J; Department of Pediatric Oncology, Emma Children's Hospital-Academic Medical Center, Amsterdam, The Netherlands., Bakx R; Pediatric Surgical Center of Amsterdam, Emma Children's Hospital-Academic Medical Center and VU Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands., Heij HA; Pediatric Surgical Center of Amsterdam, Emma Children's Hospital-Academic Medical Center and VU Medical Center, P.O. Box 22660, 1100 DD, Amsterdam, The Netherlands.
المصدر: Pediatric surgery international [Pediatr Surg Int] 2017 Jan; Vol. 33 (1), pp. 23-31. Date of Electronic Publication: 2016 Oct 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8609169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1437-9813 (Electronic) Linking ISSN: 01790358 NLM ISO Abbreviation: Pediatr Surg Int Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin : Springer International, c1986-
مواضيع طبية MeSH: Hepatectomy/*methods , Hepatoblastoma/*surgery , Liver Neoplasms/*surgery , Liver Transplantation/*methods, Biopsy ; Child, Preschool ; Female ; Hepatoblastoma/diagnosis ; Hepatoblastoma/epidemiology ; Humans ; Incidence ; Infant ; Infant, Newborn ; Liver/diagnostic imaging ; Liver/surgery ; Liver Neoplasms/diagnosis ; Liver Neoplasms/epidemiology ; Male ; Margins of Excision ; Netherlands/epidemiology ; Survival Rate/trends ; Treatment Outcome ; Ultrasonography
مستخلص: Background: Achievement of complete surgical resection plays a key role in the successful treatment of children with hepatoblastoma. The aim of this study is to assess the surgical outcomes after partial liver resections for hepatoblastoma, focusing on postoperative complications, resection margins, 30-day mortality, and long-term survival.
Method: Chart reviews were carried out on all patients treated for hepatoblastoma in the Netherlands between 1990 and 2013.
Results: A total of 103 patients were included, of whom 94 underwent surgery. Partial hepatectomy was performed in 76 patients and 18 patients received a liver transplant as a primary procedure. In 42 of 73 (58 %) patients, one or more complications were reported. In 3 patients, information regarding complications was not available. Hemorrhage necessitating blood transfusion occurred in 33 (45 %) patients and 9 (12 %) patients developed biliary complications, of whom 8 needed one or more additional surgical interventions. Overall, 5-year disease-specific survival was 82, 92 % in the group of patients who underwent partial hepatectomy, and 77 % in the group of patients who underwent liver transplantation.
Conclusions: Partial hepatectomy after chemotherapy in children with hepatoblastoma offers good chances of survival. This type of major surgery is associated with a high rate of surgical complications (58 %), which is not detrimental to survival.
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فهرسة مساهمة: Keywords: Biliary complications; Hemorrhage; Hepatoblastoma; Partial hepatectomy; Postoperative complications
تواريخ الأحداث: Date Created: 20161013 Date Completed: 20170321 Latest Revision: 20181202
رمز التحديث: 20231215
DOI: 10.1007/s00383-016-3989-8
PMID: 27730288
قاعدة البيانات: MEDLINE
الوصف
تدمد:1437-9813
DOI:10.1007/s00383-016-3989-8