دورية أكاديمية
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex.
| العنوان: | Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. |
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| المؤلفون: | Guadalupe T; Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.; International Max Planck Research School for Language Sciences, Nijmegen, The Netherlands., Mathias SR; Department of Psychiatry, Yale School of Medicine, New Haven, CT, 06519, USA., vanErp TGM; Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA., Whelan CD; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey, CA, USA.; Molecular and Cellular Therapeutics, The Royal College of Surgeons, Dublin 2, Ireland., Zwiers MP; Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands., Abe Y; Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan., Abramovic L; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands., Agartz I; NORMENT - KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Research and Development, Diakonhjemmet Hospital, Oslo, Norway.; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden., Andreassen OA; NORMENT - KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Arias-Vásquez A; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands.; Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands., Aribisala BS; Department of Computer Science, Lagos State University, Lagos, Nigeria.; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK., Armstrong NJ; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales (UNSW), Sydney, Australia.; Mathematics and Statistics, Murdoch University, Murdoch, Australia., Arolt V; Department of Psychiatry, University of Münster, Münster, Germany., Artiges E; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 'Neuroimaging & Psychiatry', University Paris Sud, University Paris Descartes -Sorbonne Paris Cité, Paris, France., Ayesa-Arriola R; Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Santander, Spain., Baboyan VG; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Los Angeles, USA., Banaschewski T; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany., Barker G; Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Bastin ME; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK., Baune BT; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, 5005, Australia., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Bokde ALW; Discipline of Psychiatry, School of Medicine and Trinity College Institute of Neurosciences, Trinity College Dublin, Dublin, Ireland., Boedhoe PSW; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands.; Department of Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands.; Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands., Bose A; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India., Brem S; University Clinic for and Adolescent Psychiatry UCCAP, University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland., Brodaty H; Centre for Healthy Brain Ageing (CHeBA), & Dementia Collaborative Research Centre, School of Psychiatry, UNSW Medicine, University of New South Wales, Sydney, Australia., Bromberg U; University Medical Centre Hamburg-Eppendorf, House W34, 3.OG, Martinistr. 52, 20246, Hamburg, Germany., Brooks S; Department of Psychiatry, University of Cape Town, Cape Town, South Africa., Büchel C; University Medical Centre Hamburg-Eppendorf, House W34, 3.OG, Martinistr. 52, 20246, Hamburg, Germany., Buitelaar J; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands.; Karakter Child and Adolescent Psychiatry, Radboud university medical center, Nijmegen, The Netherlands., Calhoun VD; Departments of Electrical and Computer Engineering,Neurosciences, Computer Science, and Psychiatry, The University of New Mexico, Albuquerque, NM, USA.; The Mind Research Network, Albuquerque, NM, USA., Cannon DM; Centre for Neuroimaging, Cognition & Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, H91 TK33, Ireland., Cattrell A; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Cheng Y; Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming, China., Conrod PJ; Department of Psychiatry, Universite de Montreal, CHU Ste Justine Hospital, Montréal, Canada.; Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Conzelmann A; Department of Psychology (Biological Psychology, Clinical Psychology, and Psychotherapy), University of Würzburg, Germany, Tübingen, Würzburg, Germany.; Department of Child and Adolescent Psychiatry and Psychotherapy, University of Tübingen, Tübingen, Germany., Corvin A; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland., Crespo-Facorro B; Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Santander, Spain., Crivello F; UMR5296 CNRS, CEA and University of Bordeaux, Bordeaux, France., Dannlowski U; Department of Psychiatry, University of Münster, Münster, Germany.; Department of Psychiatry, University of Marburg, Marburg, Germany., de Zubicaray GI; Faculty of Health and Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane City, Australia., de Zwarte SMC; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh, UK., Desrivières S; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Doan NT; NORMENT - KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Donohoe G; Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition & Genomics Centre (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, SW4 794, Galway, Ireland.; Department of Psychiatry & trinity College Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., Dørum ES; NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Sunnaas Rehabilitation Hospital HT, Nesodden, Norway.; Department of Psychology, University of Oslo, Oslo, Norway., Ehrlich S; Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Dresden, Germany.; Department of Psychiatry, Massachusetts General Hospital, Boston, USA.; Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, USA., Espeseth T; NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT - KG Jebsen Centre, Department of Psychology, University of Oslo, Oslo, Norway., Fernández G; Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands., Flor H; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, Mannheim, Germany., Fouche JP; Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa., Frouin V; Neurospin, Commissariat à l'Energie Atomique, CEA-Saclay Center, Paris, France., Fukunaga M; Division of Cerebral Integration, National Institute for Physiological Sciences, Okazaki, Japan., Gallinat J; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany., Garavan H; Departments of Psychiatry and Psychology, University of Vermont, Burlington, VT, 05405, USA., Gill M; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; Trinity College Institute of Neuroscience, Trinity College, Dublin, Ireland., Suarez AG; Service of Neurology, University Hospital Marqués de Valdecilla (IDIVAL), University of Cantabria (UC), Santander, Spain.; CIBERNED, Centro de Investigación Biomédica en red Enfermedades Neurodegenerativas, Madrid, Spain., Gowland P; Sir Peter Mansfield Imaging Centre School of Physics and Astronomy, University of Nottingham, University Park, Nottingham, UK., Grabe HJ; Department of Psychiatry, University Medicine Greifswald, Greifswald, Germany.; Department of Psychiatry and Psychotherapy, HELIOS Hospital Stralsund, Stralsund, Germany., Grotegerd D; Department of Psychiatry, University of Münster, Münster, Germany., Gruber O; Center for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center, D-37075, Göttingen, Germany., Hagenaars S; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hashimoto R; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Osaka, Japan.; Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan., Hauser TU; University Clinic for Child and Adolescent Psychiatry (UCCAP), University of Zurich, Zurich, Switzerland.; Wellcome Trust Centre for Neuroimaging, University College London, London, UK.; UCL Max Planck Centre for Computational Psychiatry and Ageing, University College London, London, UK., Heinz A; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany., Hibar DP; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey, CA, USA., Hoekstra PJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Hoogman M; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands., Howells FM; Department of Psychiatry, University of Cape Town, Cape Town, South Africa., Hu H; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, No. 600 Wan Ping Nan Road, Shanghai, 200030, China., Hulshoff Pol HE; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands., Huyser C; De Bascule, Academic Center for Child and Adolescent Psychiatry, Amsterdam, The Netherlands.; AMC, department of child and adolescent psychiatry, Amsterdam, The Netherlands., Ittermann B; Physikalisch-Technische Bundesanstalt (PTB), Braunschweig and Berlin, Germany., Jahanshad N; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Los Angeles, USA., Jönsson EG; Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden.; NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine. Psychiatry section, University of Oslo, Oslo, Norway., Jurk S; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany., Kahn RS; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands., Kelly S; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Los Angeles, 90292, USA., Kraemer B; Center for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center, D-37075, Göttingen, Germany., Kugel H; Department of Clinical Radiology, University of Münster, Münster, Germany., Kwon JS; Department of Psychiatry & Behavioral Science, Seoul National University College of Medicine, Seoul, Republic of Korea.; Institute of Human Behavioral Medicine, SNU-MRC, Seoul, Republic of Korea.; Department of Brain & Cognitive Sciences, College of Natural Science, Seoul National University, Seoul, Republic of Korea., Lemaitre H; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 'Neuroimaging & Psychiatry', University Paris Sud, University Paris Descartes -Sorbonne Paris Cité, Paris, France., Lesch KP; Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.; Department of Translational Neuroscience, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands., Lochner C; Department of Psychiatry, University of Stellenbosch and MRC Unit on Anxiety & Stress Disorders, Tygerberg, Cape Town, South Africa., Luciano M; Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh, UK., Marquand AF; Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College London, London, UK., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Martínez-Zalacaín I; Department of Psychiatry, Bellvitge University Hospital - Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain., Martinot JL; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 'Neuroimaging & Psychiatry', University Paris Sud, University Paris Descartes - Sorbonne Paris Cité, and Maison de Solenn, Paris, France.; Maison de Solenn, Paris, France., Mataix-Cols D; Department of Clinical Neuroscience,Centre for Psychiatric Research and Education, Karolinska Institutet, Stockholm, Sweden., Mather K; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales (UNSW), Sydney, Australia., McDonald C; Centre for Neuroimaging, Cognition & Genomics (NICOG), Clinical Neuroimaging Laboratory, NCBES Galway Neuroscience Centre, College of Medicine, Nursing and Health Sciences, National University of Ireland Galway, Galway, H91 TK33, Ireland., McMahon KL; Centre for Advanced Imaging, University of Queensland, Brisbane, Australia., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Menchón JM; Department of Psychiatry, Bellvitge University Hospital - Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain.; CIBER Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain.; Department of Clinical Sciences, University of Barcelona, Barcelona, Spain., Morris DW; Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition & Genomics Centre (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, SW4 794, Galway, Ireland., Mothersill O; Department of Psychiatry, Trinity College Dublin, Dublin, Ireland.; Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition & Genomics Centre (NICOG), School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, SW4 794, Galway, Ireland., Maniega SM; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Mwangi B; UT Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, UT Houston Medical School, Houston, TX, USA., Nakamae T; Department of Psychiatry, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.; Department of Neural Computation for Decision-Making, ATR Brain Information Communication Research Laboratory Group, Kyoto, Japan., Nakao T; Department of Neuropsychiatry, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan., Narayanaswaamy JC; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India., Nees F; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, Mannheim, Germany., Nordvik JE; Sunnaas Rehabilitation Hospital HT, Nesodden, Norway., Onnink AMH; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands., Opel N; Department of Psychiatry, University of Münster, Münster, Germany., Ophoff R; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands.; Center for Neurobehavioral Genetics, University of California, Los Angeles, USA., Paillère Martinot ML; Institut National de la Santé et de la Recherche Médicale, INSERM Unit 1000 'Neuroimaging & Psychiatry', University Paris Sud, University Paris Descartes -Sorbonne Paris Cité, Paris, France.; AP-HP, Department of Adolescent Psychopathology and Medicine, Maison de Solenn, Cochin Hospital, Paris, France., Papadopoulos Orfanos D; Neurospin, Commissariat à l'Energie Atomique, CEA-Saclay Center, Paris, France., Pauli P; Department of Psychiatry and Psychotherapy, University of Würzburg, Würzburg, Germany., Paus T; Rotman Research Institute, Baycrest and Departments of Psychology and Psychiatry, University of Toronto, M6A 2E1, Toronto, ON, Canada., Poustka L; Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159, Mannheim, Germany.; Department of Child and Adolescent Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria., Reddy JY; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India., Renteria ME; QIMR Berghofer Medical Research Institute, Brisbane, Australia., Roiz-Santiáñez R; Department of Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, Santander, Spain.; CIBERSAM, Centro Investigación Biomédica en Red Salud Mental, Santander, Spain., Roos A; Department of Psychiatry, University of Stellenbosch and MRC Unit on Anxiety & Stress Disorders, Tygerberg, Cape Town, South Africa., Royle NA; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Sachdev P; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales (UNSW), Sydney, Australia., Sánchez-Juan P; Service of Neurology, University Hospital Marqués de Valdecilla (IDIVAL), University of Cantabria (UC), Santander, Spain.; CIBERNED, Centro de Investigación Biomédica en red Enfermedades Neurodegenerativas, Madrid, Spain., Schmaal L; Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Schumann G; Medical Research Council - Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK., Shumskaya E; Donders Centre for Cognitive Neuroimaging, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands.; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands., Smolka MN; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany., Soares JC; Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, TX, 77054, USA., Soriano-Mas C; Department of Psychiatry, Bellvitge University Hospital - Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Barcelona, Spain.; CIBER Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain.; Department of Psychobiology and Methodology of Health Sciences, Universitat Autònoma de Barcelona, Barcelona, Spain., Stein DJ; Department of Psychiatry, University of Cape Town and MRC Unit on Anxiety & Stress Disorders, Cape Town, South Africa., Strike LT; Queensland Brain Institute, The University of Queensland, Brisbane, Australia., Toro R; Laboratory of Human Genetics and Cognitive Functions, Institut Pasteur, 75015, Paris, France., Turner JA; The Mind Research Network, Albuquerque, NM, USA.; Department of Psychology, Georgia State University, Atlanta, GA, USA.; Department of Neuroscience, Georgia State University, Atlanta, GA, USA., Tzourio-Mazoyer N; UMR5296 CNRS, CEA and University of Bordeaux, Bordeaux, France., Uhlmann A; Department of Psychiatry and Mental Health, University of Cape Town, Observatory, Cape Town, South Africa., Hernández MV; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., van den Heuvel OA; Department of Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands.; Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands.; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands., van der Meer D; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Haren NEM; Brain Centre Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands., Veltman DJ; Department of Psychiatry, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, The Netherlands., Venkatasubramanian G; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India., Vetter NC; Department of Psychiatry and Neuroimaging Center, Technische Universität Dresden, Dresden, Germany., Vuletic D; Department of Psychiatry, University of Cape Town, Cape Town, South Africa., Walitza S; University Clinic for Child and Adolescent Psychiatry (UCCAP), University of Zurich, Zurich, Switzerland.; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland., Walter H; Department of Psychiatry and Psychotherapy, Campus Charité Mitte, Charité, Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany., Walton E; Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Dresden, Germany.; Department of Psychology, Georgia State University, Atlanta, GA, USA., Wang Z; Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, No. 600 Wan Ping Nan Road, Shanghai, 200030, China., Wardlaw J; Brain Research Imaging Centre, University of Edinburgh, Edinburgh, UK.; Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.; Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Department of Neuroimaging Sciences, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Wen W; Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales (UNSW), Sydney, Australia., Westlye LT; NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; Department of Psychology, University of Oslo, Oslo, Norway., Whelan R; Department of Psychology, University College Dublin, Dublin, Ireland., Wittfeld K; German Center for Neurodegenerative Diseases (DZNE), Site Rostock, Greifswald, Germany., Wolfers T; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands., Wright MJ; QIMR Berghofer Medical Research Institute, Brisbane, Australia.; Queensland Brain Institute and Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia., Xu J; Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming, China., Xu X; Department of Psychiatry, The First Affiliated Hospital of Kunming Medical University, Kunming, China., Yun JY; Seoul National University Hospital, Seoul, Republic of Korea., Zhao J; Cognitive Genetics and Therapy Group, School of Psychology & Discipline of Biochemistry, National University of Ireland Galway, Galway, SW4 794, Ireland.; School of Psychology, Shaanxi Normal University, Xi'an, China., Franke B; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud university medical center, Nijmegen, The Netherlands.; Department of Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Thompson PM; Imaging Genetics Center, Institute for Neuroimaging & Informatics, Keck School of Medicine of the University of Southern California, Marina del Rey, CA, USA., Glahn DC; Department of Psychiatry, Yale University, New Haven, CT, 06511, USA.; Olin Neuropsychiatric Research Center, Hartford, CT, 06114, USA., Mazoyer B; UMR5296 CNRS, CEA and University of Bordeaux, Bordeaux, France., Fisher SE; Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands.; Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands., Francks C; Language & Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, The Netherlands. clyde.francks@mpi.nl.; Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands. clyde.francks@mpi.nl. |
| المصدر: | Brain imaging and behavior [Brain Imaging Behav] 2017 Oct; Vol. 11 (5), pp. 1497-1514. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 101300405 Publication Model: Print Cited Medium: Internet ISSN: 1931-7565 (Electronic) Linking ISSN: 19317557 NLM ISO Abbreviation: Brain Imaging Behav Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Secaucus, NJ : Springer |
| مواضيع طبية MeSH: | Functional Laterality*/genetics , Sex Characteristics*, Aging/*pathology , Brain/*diagnostic imaging, Adolescent ; Adult ; Aged ; Aging/genetics ; Brain/anatomy & histology ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Meta-Analysis as Topic ; Middle Aged ; Organ Size ; Quantitative Trait, Heritable ; Young Adult |
| مستخلص: | The two hemispheres of the human brain differ functionally and structurally. Despite over a century of research, the extent to which brain asymmetry is influenced by sex, handedness, age, and genetic factors is still controversial. Here we present the largest ever analysis of subcortical brain asymmetries, in a harmonized multi-site study using meta-analysis methods. Volumetric asymmetry of seven subcortical structures was assessed in 15,847 MRI scans from 52 datasets worldwide. There were sex differences in the asymmetry of the globus pallidus and putamen. Heritability estimates, derived from 1170 subjects belonging to 71 extended pedigrees, revealed that additive genetic factors influenced the asymmetry of these two structures and that of the hippocampus and thalamus. Handedness had no detectable effect on subcortical asymmetries, even in this unprecedented sample size, but the asymmetry of the putamen varied with age. Genetic drivers of asymmetry in the hippocampus, thalamus and basal ganglia may affect variability in human cognition, including susceptibility to psychiatric disorders. |
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| معلومات مُعتمدة: | MC_UU_12013/2 United Kingdom MRC_ Medical Research Council; R01 EB015611 United States EB NIBIB NIH HHS; MC_UU_12013/1 United Kingdom MRC_ Medical Research Council; MR/M013111/1 United Kingdom MRC_ Medical Research Council; R01 MH078111 United States MH NIMH NIH HHS; G1001245 United Kingdom MRC_ Medical Research Council; U54 EB020403 United States EB NIBIB NIH HHS; UL1 RR025758 United States RR NCRR NIH HHS; R01 MH083824 United States MH NIMH NIH HHS; G0701120 United Kingdom MRC_ Medical Research Council; R01 MH090553 United States MH NIMH NIH HHS; MR/K026992/1 United Kingdom MRC_ Medical Research Council |
| فهرسة مساهمة: | Keywords: Age; Enigma; Handedness; Heritability; Meta-analysis; Sex; Subcortical brain asymmetry |
| تواريخ الأحداث: | Date Created: 20161015 Date Completed: 20180611 Latest Revision: 20231112 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC5540813 |
| DOI: | 10.1007/s11682-016-9629-z |
| PMID: | 27738994 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1931-7565 |
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| DOI: | 10.1007/s11682-016-9629-z |