دورية أكاديمية
Can progression of odontogenic infections to cervical necrotizing soft tissue infections be predicted?
| العنوان: | Can progression of odontogenic infections to cervical necrotizing soft tissue infections be predicted? |
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| المؤلفون: | Zemplenyi K; Department of Oral and Maxillofacial Surgery, University of Washington, Seattle, WA, USA., Lopez B; School of Dentistry, University of Washington, Seattle, WA, USA., Sardesai M; Department of Otolaryngology Head and Neck Surgery, University of Washington, Seattle, WA, USA., Dillon JK; Department of Oral and Maxillofacial Surgery, University of Washington, Seattle, WA, USA. Electronic address: dillonj5@uw.edu. |
| المصدر: | International journal of oral and maxillofacial surgery [Int J Oral Maxillofac Surg] 2017 Feb; Vol. 46 (2), pp. 181-188. Date of Electronic Publication: 2016 Oct 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Churchill Livingstone Country of Publication: Denmark NLM ID: 8605826 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0020 (Electronic) Linking ISSN: 09015027 NLM ISO Abbreviation: Int J Oral Maxillofac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Copenhagen : Churchill Livingstone Original Publication: Copenhagen : Munksgaard, c1986- |
| مواضيع طبية MeSH: | Neck*, Fasciitis, Necrotizing/*pathology , Focal Infection, Dental/*pathology , Soft Tissue Infections/*pathology, Adult ; Biomarkers/blood ; Biopsy ; Disease Progression ; Fasciitis, Necrotizing/diagnosis ; Fasciitis, Necrotizing/therapy ; Female ; Focal Infection, Dental/diagnosis ; Focal Infection, Dental/therapy ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Retrospective Studies ; Risk Factors ; Soft Tissue Infections/diagnosis ; Soft Tissue Infections/therapy |
| مستخلص: | The progression of odontogenic infections to necrotizing soft tissue infections (NSTIs) is unknown. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score is used to predict risk of NSTI. This study aimed to (1) estimate the frequency at which odontogenic infections progress to NSTIs, (2) measure the value of LRINEC in predicting progression to NSTI, and (3) estimate the charges associated with managing NSTIs. This retrospective cohort study enrolled all subjects admitted for the management of odontogenic infections from 2001 to 2013. The primary predictor was the LRINEC score. The primary outcome was NSTI. The secondary outcome was billing charges. Descriptive and bivariate statistical analyses were performed, with significance set at a P-value of <0.05. Of 479 odontogenic infections, (1.0%) progressed to NSTI. The mean LRINEC for NSTI was 5.8 and for odontogenic infection was 3.4 (P=0.043). LRINEC parameters for the prediction of NSTIs had 60% sensitivity, 68.4% specificity, 20% positive predictive value, and 92.9% negative predictive value. The mean charge for NSTI was $319,337 and for odontogenic infections was $19,291 (P=0.051). One percent of odontogenic infections progressed to NSTIs. The LRINEC score was not able to identify all NSTIs. NSTIs are 16 times more costly. (Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: LRINEC; necrotizing soft tissue infections; odontogenic infections |
| المشرفين على المادة: | 0 (Biomarkers) |
| تواريخ الأحداث: | Date Created: 20161021 Date Completed: 20180209 Latest Revision: 20220318 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.ijom.2016.09.016 |
| PMID: | 27756512 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1399-0020 |
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| DOI: | 10.1016/j.ijom.2016.09.016 |