دورية أكاديمية
BILATERAL DIFFUSE UVEAL MELANOCYTIC PROLIFERATION ASSOCIATED WITH RENAL CANCER: THE IMPORTANCE OF INDOCYANINE GREEN ANGIOGRAPHY AND EARLY DIAGNOSIS.
| العنوان: | BILATERAL DIFFUSE UVEAL MELANOCYTIC PROLIFERATION ASSOCIATED WITH RENAL CANCER: THE IMPORTANCE OF INDOCYANINE GREEN ANGIOGRAPHY AND EARLY DIAGNOSIS. |
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| المؤلفون: | Kniggendorf VF; Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil., Neto ET; Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil., Maia EM; Department of Ophthalmology, Brazilian Institute of Fight Against Blindness, Assis and Presidente Prudente, São Paulo, Brazil., Grando JPS; Department of Ophthalmology, Brazilian Institute of Fight Against Blindness, Assis and Presidente Prudente, São Paulo, Brazil., Bardal AMC; Department of Ophthalmology, Brazilian Institute of Fight Against Blindness, Assis and Presidente Prudente, São Paulo, Brazil., Beato PMM; Department of Oncology, Hospital Fundação Amaral Carvalho, Jaú, São Paulo, Brazil., Torres CC; Department of Ophthalmology, Brazilian Institute of Fight Against Blindness, Assis and Presidente Prudente, São Paulo, Brazil., Maia M; Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.; Department of Ophthalmology, Brazilian Institute of Fight Against Blindness, Assis and Presidente Prudente, São Paulo, Brazil. |
| المصدر: | Retinal cases & brief reports [Retin Cases Brief Rep] 2018 Summer; Vol. 12 (3), pp. 166-171. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 101298744 Publication Model: Print Cited Medium: Internet ISSN: 1937-1578 (Electronic) Linking ISSN: 19351089 NLM ISO Abbreviation: Retin Cases Brief Rep Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hagerstown, MD : Wolters Kluwer Health, c2007- |
| مواضيع طبية MeSH: | Coloring Agents* , Indocyanine Green*, Early Detection of Cancer/*methods , Kidney Neoplasms/*complications , Paraneoplastic Syndromes, Ocular/*diagnostic imaging , Uveal Neoplasms/*diagnostic imaging, Fluorescein Angiography/methods ; Humans ; Male ; Middle Aged |
| مستخلص: | Purpose: To report a case of bilateral diffuse uveal melanocytic proliferation associated with renal carcinoma and to illustrate the importance of ancillary examinations to early diagnosis and treatment. Design: Clinical case report. Methods: A 56-year-old man reported a 3-day history of visual impairment and scotoma in the right eye. An ophthalmoscopic examination, visual field test, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, optical coherence tomography, and systemic evaluation were performed. Results: Fundus examination showed multiple nevus-like uveal pigmented lesions bilaterally. Optical coherence tomography showed a subfoveal serous retinal detachment and focal loss of the retinal pigment epithelium with adjacent areas of retinal pigment epithelial thickening in the right eye, explaining the scotoma on the visual field examination. Indocyanine green angiography showed multiple round areas of hypofluorescence corresponding to the nevus-like pigmented tumors seen on funduscopy, and retinal pigment epithelium damage corresponding to hypoautofluorescence on fundus autofluorescence imaging and window defects points seen on fluorescein angiography bilaterally. After bilateral diffuse uveal melanocytic proliferation diagnosis, a systemic workup showed clear cell carcinoma in the left kidney. Owing to the tumoral size, chemotherapy was administered. Conclusion: Renal carcinoma associated with bilateral diffuse uveal melanocytic proliferation is rare, and the patterns observed in the ancillary examinations, including indocyanine green angiography, are useful for early-stage diagnosis and immediate referral for systemic investigation and treatment. |
| المشرفين على المادة: | 0 (Coloring Agents) IX6J1063HV (Indocyanine Green) |
| تواريخ الأحداث: | Date Created: 20161119 Date Completed: 20180604 Latest Revision: 20180604 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1097/ICB.0000000000000479 |
| PMID: | 27861254 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1937-1578 |
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| DOI: | 10.1097/ICB.0000000000000479 |