دورية أكاديمية

Analysis of a genotype G3P[9] rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses.

التفاصيل البيبلوغرافية
العنوان: Analysis of a genotype G3P[9] rotavirus a strain that shows evidence of multiple reassortment events between animal and human rotaviruses.
المؤلفون: Bezerra DA; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil.; Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Guerra SF; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Serra AC; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Fecury PC; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Bandeira RS; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil.; Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Penha ET Jr; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Lobo PS; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil.; Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Sousa EC Jr; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil.; Virology Section, Evandro Chagas Institute, Health Surveillance Secretariat, Brazilian Ministry of Health, Ananindeua, Pará, Brazil., Linhares AC; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Soares LS; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil., Mascarenhas JD; Postgraduate Program in Virology, Evandro Chagas Institute, Ananindeua, Pará, Brazil.
المصدر: Journal of medical virology [J Med Virol] 2017 Jun; Vol. 89 (6), pp. 974-981. Date of Electronic Publication: 2016 Dec 05.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
أسماء مطبوعة: Publication: New York Ny : Wiley-Liss
Original Publication: New York, Liss.
مواضيع طبية MeSH: Genotype*, Gastroenteritis/*virology , Reassortant Viruses/*genetics , Rotavirus/*genetics , Rotavirus Infections/*virology, Child, Preschool ; Evolution, Molecular ; Female ; Humans ; Phylogeny ; Recombination, Genetic ; Rotavirus/isolation & purification ; Sequence Analysis, DNA
مستخلص: The species A rotaviruses (RVA) are important gastroenteric pathogens that infect humans and animals. RVA genotype G3P[9] has been described in human-animal reassortment events, and the complexity of its hosts motivates the genetic investigation of this strain. Therefore, the aim of this study is to analyse a G3P[9] sample that was detected in a child with acute gastroenteritis. The 1A3739 sample featured the constellation G3P[9]-I18-R3-C3-Mx-A19-N3-T3-E3-H6. The sequence for VP3 gene was not obtained. The phylogeny showed a closer relationship among genes VP7, VP1, NSP3, NSP4, and NSP5 with genes of animal origin, such as chiropter, alpaca, equine, and simian. In addition, the genes VP6 and NSP1 belong to the new genotypes I18 and A19, respectively. The emergence of strains such as these can interfere with the effectiveness of the RVA vaccine, and continuous monitoring is therefore important. Additional studies are needed to determine the evolutionary source and to identify a possible reservoir of RVA in nature.
(© 2016 Wiley Periodicals, Inc.)
فهرسة مساهمة: Keywords: G3P[9]; human rotavirus; interspecies transmission; rotavirus; sequence analysis
تواريخ الأحداث: Date Created: 20161119 Date Completed: 20170908 Latest Revision: 20181104
رمز التحديث: 20240628
DOI: 10.1002/jmv.24733
PMID: 27862014
قاعدة البيانات: MEDLINE
الوصف
تدمد:1096-9071
DOI:10.1002/jmv.24733