دورية أكاديمية

[Minocycline-induced hyperpigmentation: not uncommon, but nonetheless important to recognise].

التفاصيل البيبلوغرافية
العنوان: [Minocycline-induced hyperpigmentation: not uncommon, but nonetheless important to recognise].
عنوان ترانسليتريتد: Minocycline-geïnduceerde hyperpigmentatie.
المؤلفون: Voets PJ; Radboudumc, Nijmegen., Blommaert D, Keijsers RR, Alkemade HA
المصدر: Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2016; Vol. 160, pp. D483.
نوع المنشور: Case Reports; Journal Article
اللغة: Dutch; Flemish
بيانات الدورية: Publisher: Vereniging NTvG Country of Publication: Netherlands NLM ID: 0400770 Publication Model: Print Cited Medium: Internet ISSN: 1876-8784 (Electronic) Linking ISSN: 00282162 NLM ISO Abbreviation: Ned Tijdschr Geneeskd Subsets: MEDLINE
أسماء مطبوعة: Publication: 2017?-: Amsterdam : Vereniging NTvG
Original Publication: Houten : Bohn Stafleu van Loghum
مواضيع طبية MeSH: Anti-Bacterial Agents/*therapeutic use , Hyperpigmentation/*chemically induced , Minocycline/*adverse effects, Acne Vulgaris/drug therapy ; Adult ; Biopsy ; Dose-Response Relationship, Drug ; Humans ; Hyperpigmentation/pathology ; Leg/pathology ; Male ; Minocycline/administration & dosage ; Skin/drug effects
مستخلص: Background: Minocycline, a broad-spectrum antibiotic from the group of tetracyclins, is frequently prescribed for acne vulgaris and rosacea. Hyperpigmentation is a relatively common side effect of this drug and can lead to multiple unsightly skin lesions, which are not always reversible. It can take a long period, from a few months to several years, before the lesions have completely vanished.
Case Description: A 24-year-old male was seen in our outpatient clinic because of slowly progressive pigmented lesions on his shins. His medical history included chronic use of minocycline for the treatment of acne vulgaris. Based on the morphology of the lesions, the patient's medical history and analysis of a skin biopsy, the diagnosis 'minocycline-induced hyperpigmentation type 2'was made.
Conclusion: Hyperpigmentation is a relatively common and undesirable side-effect of minocycline use. Long-term prescription of this drug for more than one year should therefore be considered with caution, especially if the dose exceeds 100 milligrams per day.
المشرفين على المادة: 0 (Anti-Bacterial Agents)
FYY3R43WGO (Minocycline)
تواريخ الأحداث: Date Created: 20161124 Date Completed: 20180222 Latest Revision: 20180807
رمز التحديث: 20221213
PMID: 27879178
قاعدة البيانات: MEDLINE