Accumulation and Determination of Phenylethanolamine A Residue in Hair of Swine and Sheep.

التفاصيل البيبلوغرافية
العنوان:	Accumulation and Determination of Phenylethanolamine A Residue in Hair of Swine and Sheep.
المؤلفون:	Decheng S; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Ruiguo W; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Peilong W; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Genlong Z; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Yufei F; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Xia F; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Yang L; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China., Xiaoou S; Institute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Science, No. 12 South Street, Zhongguancun, Beijing 100081, China.
المصدر:	Journal of analytical toxicology [J Anal Toxicol] 2017 Mar 01; Vol. 41 (2), pp. 146-152.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Oxford University Press Country of Publication: England NLM ID: 7705085 Publication Model: Print Cited Medium: Internet ISSN: 1945-2403 (Electronic) Linking ISSN: 01464760 NLM ISO Abbreviation: J Anal Toxicol Subsets: MEDLINE
أسماء مطبوعة:	Publication: 2012- : Oxford : Oxford University Press Original Publication: 1977-<2011>: Niles, Ill., Preston Publications.
مواضيع طبية MeSH:	2-Hydroxyphenethylamine/analogs & derivatives , Adrenergic beta-Agonists/analysis , Drug Residues/analysis , Hair/chemistry , Substance Abuse Detection/methods , Substance Abuse Detection/veterinary, 2-Hydroxyphenethylamine/analysis ; Animals ; Chromatography, Liquid ; Female ; Male ; Sheep ; Substance Abuse Detection/instrumentation ; Swine ; Tandem Mass Spectrometry
مستخلص:	The present study proposed the use of liquid chromatography-tandem mass spectrometry to detect the novel β-agonist phenylethanolamine A (PEA) in incurred hair samples of swine and sheep and to assess its accumulation for residue monitoring. The method showed good percent recoveries ranging from 93.2% to 102% and good coefficient of variation at <15%. The experiment was conducted in swine (24 treated and 4 controls) and sheep (3 treated and 1 control). PEA concentration was determined in hair during the treatment. High residue concentrations were present in hair as early as Day 24 (14.8 ± 3.6 and 25.8 ± 7.6 ng/g) and Day 21 (23.4 ± 6.6 ng/g) for swine and sheep; these residues persisted until withdrawal on Days 14 and 21. Results showed high PEA accumulation in hair, thereby indicating the use of hair as a matrix in the control of PEA abuse in farm animals. (© The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
المشرفين على المادة:	0 (2-(4-(nitrophenyl)butan-2-ylamino)-1-(4-methoxyphenyl)ethanol) 0 (Adrenergic beta-Agonists) 7568-93-6 (2-Hydroxyphenethylamine)
تواريخ الأحداث:	Date Created: 20161125 Date Completed: 20170525 Latest Revision: 20170525
رمز التحديث:	20231215
DOI:	10.1093/jat/bkw121
PMID:	27881619
قاعدة البيانات:	MEDLINE

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تدمد:	1945-2403
DOI:	10.1093/jat/bkw121