دورية أكاديمية
Nipple- and areola-sparing mastectomy for the treatment of breast cancer.
| العنوان: | Nipple- and areola-sparing mastectomy for the treatment of breast cancer. |
|---|---|
| المؤلفون: | Mota BS; Department of Obstetrics and Gynecology, Instituto do câncer de São Paulo (ICESP/FMUSP), Av. Dr Arnaldo 251, Sao Paulo, Sao Paulo, Brazil, 01246-000., Riera R, Ricci MD, Barrett J, de Castria TB, Atallah ÁN, Bevilacqua JL |
| المصدر: | The Cochrane database of systematic reviews [Cochrane Database Syst Rev] 2016 Nov 29; Vol. 11. Cochrane AN: CD008932. Date of Electronic Publication: 2016 Nov 29. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Review; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: England NLM ID: 100909747 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-493X (Electronic) Linking ISSN: 13616137 NLM ISO Abbreviation: Cochrane Database Syst Rev Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2004- : Chichester, West Sussex, England : Wiley Original Publication: Oxford, U.K. ; Vista, CA : Update Software, |
| مواضيع طبية MeSH: | Nipples*, Breast Neoplasms/*surgery , Carcinoma, Intraductal, Noninfiltrating/*surgery , Mastectomy/*methods , Organ Sparing Treatments/*methods, Breast Neoplasms/mortality ; Carcinoma, Intraductal, Noninfiltrating/mortality ; Cohort Studies ; Female ; Humans ; Mastectomy/adverse effects ; Mastectomy/mortality ; Neoplasm Recurrence, Local ; Organ Sparing Treatments/adverse effects ; Postoperative Complications ; Skin |
| مستخلص: | Background: The efficacy and safety of nipple-sparing mastectomy and areola-sparing mastectomy for the treatment of breast cancer are still questionable. It is estimated that the local recurrence rates following nipple-sparing mastectomy are very similar to breast-conserving surgery followed by radiotherapy. Objectives: To assess the efficacy and safety of nipple-sparing mastectomy and areola-sparing mastectomy for the treatment of ductal carcinoma in situ and invasive breast cancer in women. Search Methods: We searched the Cochrane Breast Cancer Group's Specialized Register, the Cochrane Center Register of Controlled Trials (CENTRAL), MEDLINE (via PubMed), Embase (via OVID) and LILACS (via Biblioteca Virtual em Saúde [BVS]) using the search terms "nipple sparing mastectomy" and "areola-sparing mastectomy". Also, we searched the World Health Organization's International Clinical Trials Registry Platform and ClinicalTrials.gov. All searches were conducted on 30th September 2014 and we did not apply any language restrictions. Selection Criteria: Randomised controlled trials (RCTs) however if there were no RCTs, we expanded our criteria to include non-randomised comparative studies (cohort and case-control studies). Studies evaluated nipple-sparing and areola-sparing mastectomy compared to modified radical mastectomy or skin-sparing mastectomy for the treatment of ductal carcinoma in situ or invasive breast cancer. Data Collection and Analysis: Two review authors (BS and RR) performed data extraction and resolved disagreements. We performed descriptive analyses and meta-analyses of the data using Review Manager software. We used Cochrane's risk of bias tool to assess studies, and adapted it for non-randomised studies, and we evaluated the quality of the evidence using GRADE criteria. Main Results: We included 11 cohort studies, evaluating a total of 6502 participants undergoing 7018 procedures: 2529 underwent a nipple-sparing mastectomy (NSM), 818 underwent skin-sparing mastectomy (SSM) and 3671 underwent traditional mastectomy, also known as modified radical mastectomy (MRM). No participants underwent areola-sparing mastectomy. There was a high risk of confounding for all reported outcomes. For overall survival, the hazard ratio (HR) for NSM compared to SSM was 0.70 (95% CI 0.28 to 1.73; 2 studies; 781 participants) and the HR for NSM compared to MRM was 0.72 (95% CI 0.46 to 1.13; 2 studies, 1202 participants). Local recurrence was evaluated in two studies, the HR for NSM compared to MRM was 0.28 (95% CI 0.12 to 0.68; 2 studies, 1303 participants). The overall risk of complications was different in NSM when compared to other types of mastectomy in general (RR 0.10, 95% CI 0.01 to 0.82, 2 studies, P = 0.03; 1067 participants). With respect to skin necrosis, there was no evidence of a difference with NSM compared to other types of mastectomy, but the confidence interval was wide (RR 4.22, 95% CI 0.59 to 30.03, P = 0.15; 4 studies, 1948 participants). We observed no difference among the three types of mastectomy with respect to the risk of local infection (RR 0.95, 95% CI 0.44 to 2.09, P = 0.91, 2 studies; 496 participants). Meta-analysis was not possible when assessing cosmetic outcomes and quality of life, but in general the NSM studies reported a favourable aesthetic result and a gain in quality of life compared with the other types of mastectomy. The quality of evidence was considered very low for all outcomes due to the high risk of selection bias and wide confidence intervals. Authors' Conclusions: The findings from these observational studies of very low-quality evidence were inconclusive for all outcomes due to the high risk of selection bias. |
| References: | Plast Reconstr Surg. 1977 Apr;59(4):535-7. (PMID: 847031) Ann Surg Oncol. 1999 Sep;6(6):609-13. (PMID: 10493632) Breast. 2012 Jun;21(3):267-71. (PMID: 21435877) Plast Reconstr Surg. 2010 Nov;126(5):1460-71. (PMID: 21042102) J Chir (Paris). 2007 Nov-Dec;144(6):516-21. (PMID: 18235364) Am J Surg Pathol. 1980 Dec;4(6):543-9. (PMID: 7212147) Ann Surg. 1990 Mar;211(3):250-9. (PMID: 2106841) Breast J. 2014 Jan-Feb;20(1):15-21. (PMID: 24438063) Am J Surg. 2004 Oct;188(4):403-6. (PMID: 15474435) Arch Surg. 1981 Sep;116(9):1139-40. (PMID: 7283709) BMJ. 2008 Apr 26;336(7650):924-6. (PMID: 18436948) Ann Surg Oncol. 2010 Oct;17 Suppl 3:245-8. (PMID: 20853041) Ann Surg Oncol. 2015 Oct;22(10):3241-9. (PMID: 26242363) Ann Surg Oncol. 2013 Oct;20(10):3294-302. (PMID: 23975304) Plast Reconstr Surg. 2013 Nov;132(5):1043-54. (PMID: 23924650) Breast Care (Basel). 2012 Apr;7(2):131-136. (PMID: 22740800) Breast Cancer. 2013 Jan;20(1):54-61. (PMID: 22038670) J Am Coll Surg. 2006 Nov;203(5):704-14. (PMID: 17084333) Stat Med. 1998 Dec 30;17(24):2815-34. (PMID: 9921604) Eur J Surg Oncol. 2006 Nov;32(9):937-40. (PMID: 16829015) Ann Plast Surg. 2012 Oct;69(4):425-8. (PMID: 22964678) Plast Reconstr Surg. 2014 Aug;134(2):202e-206e. (PMID: 25068341) Am J Surg. 2015 Jan;209(1):212-7. (PMID: 24946727) Ann Surg. 2010 Mar;251(3):493-8. (PMID: 20134317) Cancer. 1985 May 15;55(10):2459-63. (PMID: 2985236) J Cancer Res Clin Oncol. 1987;113(5):481-7. (PMID: 3040768) Res Synth Methods. 2013 Mar;4(1):36-47. (PMID: 26053538) Aesthet Surg J. 2011 Mar;31(3):310-9. (PMID: 21385742) Am J Surg. 1989 Nov;158(5):399-403. (PMID: 2817219) J Surg Oncol. 2013 Sep;108(4):207-12. (PMID: 23913775) Eur J Surg Oncol. 2008 Feb;34(2):143-8. (PMID: 17709228) Ann Surg. 1979 Mar;189(3):367-72. (PMID: 218505) Eur J Surg Oncol. 2000 Jun;26(4):351-6. (PMID: 10873354) Indian J Cancer. 1997 Mar;34(1):1-5. (PMID: 9491654) J Natl Cancer Inst. 2001 Nov 7;93(21):1633-7. (PMID: 11698567) BMJ. 2003 Sep 6;327(7414):557-60. (PMID: 12958120) Aesthetic Plast Surg. 1989 Winter;13(1):15-21. (PMID: 2728994) Plast Surg Int. 2014;2014:589068. (PMID: 25478220) Ann Surg Oncol. 2012 Apr;19(4):1137-44. (PMID: 21979111) Ann Surg Oncol. 2008 May;15(5):1341-7. (PMID: 18256883) Ann Surg Oncol. 2011 Apr;18(4):917-22. (PMID: 21308484) J Plast Reconstr Aesthet Surg. 2010 Oct;63(10):e754-5. (PMID: 20598664) Am J Surg. 1979 Jul;138(1):135-42. (PMID: 223463) Tumori. 2003 May-Jun;89(3):288-91. (PMID: 12908785) Ann Surg Oncol. 2002 Mar;9(2):165-8. (PMID: 11888874) Med Oncol. 2013 Mar;30(1):481. (PMID: 23377926) Am J Surg. 2008 Mar;195(3):391-4; discussion 394-5. (PMID: 18207131) Surg Oncol. 2008 Dec;17(4):261-6. (PMID: 18456492) Plast Reconstr Surg. 2011 Nov;128(5):1005-14. (PMID: 21738086) Plast Reconstr Surg. 2014 Aug;134(2):169-75. (PMID: 24732652) Ann Plast Surg. 2014 Nov;73(5):485-91. (PMID: 24378808) Ann Surg. 2009 Mar;249(3):461-8. (PMID: 19247035) Arch Surg. 2008 Nov;143(11):1106-10; discussion 1110. (PMID: 19015470) BMC Cancer. 2010 Apr 29;10:171. (PMID: 20429922) N Engl J Med. 2002 Oct 17;347(16):1227-32. (PMID: 12393819) Breast Cancer Res Treat. 2013 Aug;140(3):545-55. (PMID: 23897416) Ann Surg. 2009 Aug;250(2):288-92. (PMID: 19638905) J Am Coll Surg. 2011 Apr;212(4):686-93; discussion 693-5. (PMID: 21463813) Ann Surg Oncol. 2011 Oct;18(11):3117-22. (PMID: 21847697) Ann Surg Oncol. 2013 Mar;20(3):990-6. (PMID: 23070785) Eur J Surg Oncol. 2014 Oct;40(10):1209-15. (PMID: 25186915) Br J Surg. 2008 Nov;95(11):1356-61. (PMID: 18844271) Eur J Surg Oncol. 2012 Feb;38(2):125-9. (PMID: 22056645) Am J Surg. 2008 Oct;196(4):575-7. (PMID: 18809066) Scand J Surg. 2010;99(3):115-8. (PMID: 21044925) Aesthetic Plast Surg. 2014 Apr;38(2):338-43. (PMID: 24477519) Updates Surg. 2013 Dec;65(4):289-94. (PMID: 23888375) Ann Surg Oncol. 2003 Mar;10(2):95-7. (PMID: 12620899) Breast Cancer Res Treat. 2009 Mar;114(1):97-101. (PMID: 18360773) Ann Oncol. 2012 Aug;23(8):2053-8. (PMID: 22231025) CA Cancer J Clin. 2002 Sep-Oct;52(5):277-300. (PMID: 12363326) Arch Surg. 2008 Jan;143(1):38-45; discussion 45. (PMID: 18209151) Plast Reconstr Surg Transplant Bull. 1962 Dec;30:676-82. (PMID: 13959443) J Surg Oncol. 1980;14(2):173-93. (PMID: 7392640) Anticancer Res. 2001 Jul-Aug;21(4B):2963-7. (PMID: 11712794) Cochrane Database Syst Rev. 2010 Nov 10;(11):CD002748. (PMID: 21069671) Breast Cancer Res Treat. 2006 Mar;96(1):47-51. (PMID: 16261402) Ann Surg Oncol. 2011 Jun;18(6):1665-70. (PMID: 21174155) Ann Surg Oncol. 2008 Dec;15(12):3396-401. (PMID: 18923874) Ann Plast Surg. 2006 May;56(5):498-504; discussion 504. (PMID: 16641624) Eur J Surg Oncol. 1998 Feb;24(1):15-6. (PMID: 9542508) Ann Surg. 2009 Jan;249(1):26-32. (PMID: 19106672) Ann Intern Med. 2010 Jun 1;152(11):726-32. (PMID: 20335313) Surg Gynecol Obstet. 1976 Oct;143(4):546-8. (PMID: 183296) Br J Cancer. 1989 Jan;59(1):81-4. (PMID: 2547416) Breast Cancer Res Treat. 2009 Sep;117(2):333-8. (PMID: 19152026) Breast. 2008 Feb;17(1):8-11. (PMID: 17870535) Nihon Geka Gakkai Zasshi. 1994 Dec;95(12):887-92. (PMID: 7877587) Breast J. 2009 Jul-Aug;15(4):440-9. (PMID: 19496781) J Plast Reconstr Aesthet Surg. 2008 Oct;61(10):1195-8. (PMID: 17901007) |
| معلومات مُعتمدة: | MC_U105261167 United Kingdom MRC_ Medical Research Council |
| تواريخ الأحداث: | Date Created: 20161130 Date Completed: 20170110 Latest Revision: 20220410 |
| رمز التحديث: | 20221213 |
| مُعرف محوري في PubMed: | PMC5868722 |
| DOI: | 10.1002/14651858.CD008932.pub3 |
| PMID: | 27898991 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1469-493X |
|---|---|
| DOI: | 10.1002/14651858.CD008932.pub3 |