دورية أكاديمية
SEOM Clinical Guideline of management of soft-tissue sarcoma (2016).
| العنوان: | SEOM Clinical Guideline of management of soft-tissue sarcoma (2016). |
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| المؤلفون: | López-Pousa A; Servicio de Oncología Médica, Hospital de la Santa Creu i Sant Pau, Mas Casanovas 90, 08041, Barcelona, Spain. alopezp@santpau.cat., Martin Broto J; Hospital Virgen del Rocio, Seville, Spain., Martinez Trufero J; Hospital Universitario Miguel Servet, Saragossa, Spain., Sevilla I; Hospital Universitario Virgen de la Victoria, Malaga, Spain., Valverde C; Hospital Vall d'Hebro, Barcelona, Spain., Alvarez R; Hospital Universitario Gregorio Marañon, Madrid, Spain., Carrasco Alvarez JA; Hospital Universitario de Vigo, Vigo, Spain., Cruz Jurado J; Hospital Universitario de Canarias, Tenerife, Spain., Hindi N; Hospital Virgen del Rocio, Seville, Spain., Garcia Del Muro X; Hospital Duran I Reynals, Hospitalet de Llobregat, Spain. |
| المصدر: | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2016 Dec; Vol. 18 (12), pp. 1213-1220. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2010- >: Milan : Springer Italia Original Publication: Barcelona, Spain : Doyma, c2005- |
| مواضيع طبية MeSH: | Practice Guidelines as Topic*, Sarcoma/*diagnosis , Sarcoma/*therapy , Soft Tissue Neoplasms/*diagnosis , Soft Tissue Neoplasms/*therapy, Humans ; Neoplasm Grading ; Neoplasm Metastasis ; Spain |
| مستخلص: | Soft-tissue sarcomas are uncommon and heterogeneous tumors of mesenchymal origin. A soft-tissue mass that is increasing in size, greater than 5 cm, or located under deep fascia are criteria for suspicion of sarcoma. Diagnosis, treatment, and management should preferably be performed by a multidisciplinary team in reference centers. MRI and lung CT scan are mandatory for local and distant assessment. A biopsy indicating histological type and grade is needed previous to the treatment. Wide surgical resection with tumor-free tissue margin is the primary treatment for localized disease. Radiotherapy is indicated in large, deep, high-grade tumors, or after marginal resection not likely of being improved with reexcision. Neoadjuvant and adjuvant chemotherapy improve survival in selected cases, usually in high-grade sarcomas of the extremities. In the case of metastatic disease, patients with exclusive lung metastasis could be considered for surgery. First-line treatment with anthracyclines (or in combination with ifosfamide) is the treatment of choice. New drugs have shown activity in second-line therapy and in specific histological subtypes. Competing Interests: The authors declare that they have no conflict of interest relating to the publication of this manuscript and compliance with ethical standards. |
| References: | J Clin Oncol. 2011 Jun 20;29(18):2528-33. (PMID: 21606430) Lancet. 2016 Apr 16;387(10028):1629-37. (PMID: 26874885) Int J Surg Pathol. 2016 Feb;24(1):5-15. (PMID: 26399578) Expert Rev Anticancer Ther. 2015;15(8):901-9. (PMID: 26027711) Ann Oncol. 2016 Dec;27(12 ):2283-2288. (PMID: 27733375) J Clin Oncol. 1995 Jul;13(7):1600-8. (PMID: 7541449) Ann Surg Oncol. 2015 Jan;22(1):256-63. (PMID: 25316486) Lancet. 2012 May 19;379(9829):1879-86. (PMID: 22595799) Nat Rev Clin Oncol. 2014 Apr;11(4):187-202. (PMID: 24642677) J Clin Oncol. 2007 Jul 1;25(19):2755-63. (PMID: 17602081) Lancet. 2016 Jul 30;388(10043):488-97. (PMID: 27291997) Eur J Cancer. 2008 Apr;44(6):808-18. (PMID: 18378136) Lancet. 2002 Jun 29;359(9325):2235-41. (PMID: 12103287) J Clin Oncol. 2016 Mar 10;34(8):786-93. (PMID: 26371143) Cancer. 2008 Aug 1;113(3):573-81. (PMID: 18521899) Lancet Oncol. 2010 Jun;11(6):561-70. (PMID: 20434400) Acta Orthop Scand. 1995 Dec;66(6):561-8. (PMID: 8553829) ANZ J Surg. 2016 Mar;86(3):133-8. (PMID: 26235443) Eur J Cancer. 2015 Jan;51(2):127-36. (PMID: 25434922) Sarcoma. 2004;8(1):1-6. (PMID: 18521386) Clin Transl Oncol. 2012 Jul;14(7):541-4. (PMID: 22721800) Ann Oncol. 2012 Dec;23 (12 ):3171-9. (PMID: 22711763) Lancet Oncol. 2014 Apr;15(4):415-23. (PMID: 24618336) J Clin Oncol. 2015 Jul 10;33(20):2231-8. (PMID: 25667281) Eur J Cancer. 2015 Mar;51(5):668-74. (PMID: 25686482) |
| فهرسة مساهمة: | Keywords: Clinical guidelines; Sarcoma; Soft-tissue tumors; Uncommon tumors |
| تواريخ الأحداث: | Date Created: 20161202 Date Completed: 20170209 Latest Revision: 20190226 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC5138243 |
| DOI: | 10.1007/s12094-016-1574-1 |
| PMID: | 27905051 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1699-3055 |
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| DOI: | 10.1007/s12094-016-1574-1 |