دورية أكاديمية
SEOM Clinical Guideline of management of soft-tissue sarcoma (2016).
العنوان: | SEOM Clinical Guideline of management of soft-tissue sarcoma (2016). |
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المؤلفون: | López-Pousa A; Servicio de Oncología Médica, Hospital de la Santa Creu i Sant Pau, Mas Casanovas 90, 08041, Barcelona, Spain. alopezp@santpau.cat., Martin Broto J; Hospital Virgen del Rocio, Seville, Spain., Martinez Trufero J; Hospital Universitario Miguel Servet, Saragossa, Spain., Sevilla I; Hospital Universitario Virgen de la Victoria, Malaga, Spain., Valverde C; Hospital Vall d'Hebro, Barcelona, Spain., Alvarez R; Hospital Universitario Gregorio Marañon, Madrid, Spain., Carrasco Alvarez JA; Hospital Universitario de Vigo, Vigo, Spain., Cruz Jurado J; Hospital Universitario de Canarias, Tenerife, Spain., Hindi N; Hospital Virgen del Rocio, Seville, Spain., Garcia Del Muro X; Hospital Duran I Reynals, Hospitalet de Llobregat, Spain. |
المصدر: | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2016 Dec; Vol. 18 (12), pp. 1213-1220. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2010- >: Milan : Springer Italia Original Publication: Barcelona, Spain : Doyma, c2005- |
مواضيع طبية MeSH: | Practice Guidelines as Topic*, Sarcoma/*diagnosis , Sarcoma/*therapy , Soft Tissue Neoplasms/*diagnosis , Soft Tissue Neoplasms/*therapy, Humans ; Neoplasm Grading ; Neoplasm Metastasis ; Spain |
مستخلص: | Soft-tissue sarcomas are uncommon and heterogeneous tumors of mesenchymal origin. A soft-tissue mass that is increasing in size, greater than 5 cm, or located under deep fascia are criteria for suspicion of sarcoma. Diagnosis, treatment, and management should preferably be performed by a multidisciplinary team in reference centers. MRI and lung CT scan are mandatory for local and distant assessment. A biopsy indicating histological type and grade is needed previous to the treatment. Wide surgical resection with tumor-free tissue margin is the primary treatment for localized disease. Radiotherapy is indicated in large, deep, high-grade tumors, or after marginal resection not likely of being improved with reexcision. Neoadjuvant and adjuvant chemotherapy improve survival in selected cases, usually in high-grade sarcomas of the extremities. In the case of metastatic disease, patients with exclusive lung metastasis could be considered for surgery. First-line treatment with anthracyclines (or in combination with ifosfamide) is the treatment of choice. New drugs have shown activity in second-line therapy and in specific histological subtypes. Competing Interests: The authors declare that they have no conflict of interest relating to the publication of this manuscript and compliance with ethical standards. |
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فهرسة مساهمة: | Keywords: Clinical guidelines; Sarcoma; Soft-tissue tumors; Uncommon tumors |
تواريخ الأحداث: | Date Created: 20161202 Date Completed: 20170209 Latest Revision: 20190226 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC5138243 |
DOI: | 10.1007/s12094-016-1574-1 |
PMID: | 27905051 |
قاعدة البيانات: | MEDLINE |
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