دورية أكاديمية
Electrophysiological characterization of hearing in individuals with Down syndrome.
| العنوان: | Electrophysiological characterization of hearing in individuals with Down syndrome. |
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| عنوان ترانسليتريتد: | Caracterização eletrofisiológica da audição em indivíduos com Síndrome de Down. |
| المؤلفون: | Kazan HM; Universidade de São Paulo - USP - São Paulo (SP), Brasil., Samelli AG; Universidade de São Paulo - USP - São Paulo (SP), Brasil., Neves-Lobo IF; Universidade de São Paulo - USP - São Paulo (SP), Brasil., Magliaro FC; Universidade de São Paulo - USP - São Paulo (SP), Brasil., Limongi SC; Universidade de São Paulo - USP - São Paulo (SP), Brasil., Matas CG; Universidade de São Paulo - USP - São Paulo (SP), Brasil. |
| المصدر: | CoDAS [Codas] 2016 Nov-Dec; Vol. 28 (6), pp. 717-723. Date of Electronic Publication: 2016 Dec 12. |
| نوع المنشور: | Journal Article |
| اللغة: | Portuguese; English |
| بيانات الدورية: | Publisher: Sociedade Brasileira de Fonoaudiologia Country of Publication: Brazil NLM ID: 101623246 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2317-1782 (Electronic) Linking ISSN: 23171782 NLM ISO Abbreviation: Codas Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo : Sociedade Brasileira de Fonoaudiologia |
| مواضيع طبية MeSH: | Down Syndrome/*physiopathology , Event-Related Potentials, P300/*physiology, Acoustic Stimulation ; Adolescent ; Child ; Evoked Potentials, Auditory, Brain Stem/physiology ; Female ; Hearing Tests ; Humans ; Male |
| مستخلص: | Introduction: Few studies have performed Brainstem (BAEP) and P300 Auditory Evoked Potentials simultaneously to assess central auditory pathways in normal hearing individuals with Down syndrome (DS), mainly because of the difficulty in applying these procedures to this population. Previous studies have suggested that individuals with DS might present different patterns of response compared with those of individuals with typical development; nevertheless, the identification of these potentials would be crucial for the establishment of an accurate audiological diagnosis. Purpose: To characterize BAEP and P300 in normal-hearing individuals with DS. Methods: BAEP and P300 were analyzed in 17 individuals with DS and in 21 individuals with typical development aged 7 to 15 years. The results were quantitatively and qualitatively analyzed using descriptive measures and hypothesis tests. Results: In the quantitative analysis, latency values were lower in the BAEP for the DS group, with statistically significant difference for wave V and interpeaks III-V and I-V; there were no significant differences in the P300 latency values. In the qualitative analysis, there were a larger number of individuals with early values for BAEP latencies and late latencies for P300 in the DS group; both comparisons showed statistically significant differences. Conclusion: Children and adolescents with DS can present early responses to the components of BAEP, suggesting that their auditory pathway requires less time for the neural transmission of acoustic stimuli to the brainstem. Concerning P300, individuals with DS may present increased latencies, suggesting impairment in the central auditory pathway for the cortical processing of auditory information. |
| تواريخ الأحداث: | Date Created: 20161217 Date Completed: 20170705 Latest Revision: 20220310 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1590/2317-1782/20162015266 |
| PMID: | 27982254 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2317-1782 |
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| DOI: | 10.1590/2317-1782/20162015266 |