دورية أكاديمية
Relationship Between Abnormalities on High-Resolution Computerized Tomography, Pulmonary Function, and Bronchoalveolar Lavage in Progressive Systemic Sclerosis.
| العنوان: | Relationship Between Abnormalities on High-Resolution Computerized Tomography, Pulmonary Function, and Bronchoalveolar Lavage in Progressive Systemic Sclerosis. |
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| المؤلفون: | Cakmak G; Istanbul Haseki Education and Research Hospital,. gulfidan70@gmail.com., Selcuk Can T, Gundogdu S, Akman C, Ikitimur H, Musellim B, Ongen G |
| المصدر: | Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG [Sarcoidosis Vasc Diffuse Lung Dis] 2016 Dec 23; Vol. 33 (4), pp. 349-354. Date of Electronic Publication: 2016 Dec 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mattioli 1885 Country of Publication: Italy NLM ID: 9610928 Publication Model: Electronic Cited Medium: Internet ISSN: 2532-179X (Electronic) Linking ISSN: 11240490 NLM ISO Abbreviation: Sarcoidosis Vasc Diffuse Lung Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2000- : Parma, Italy : Mattioli 1885 Original Publication: Cormano, Milan, Italy : PCA Pub., c1996- |
| مواضيع طبية MeSH: | Bronchoalveolar Lavage* , Respiratory Function Tests* , Tomography, X-Ray Computed*, Lung/*diagnostic imaging , Lung/*physiopathology , Pulmonary Fibrosis/*diagnosis , Scleroderma, Diffuse/*diagnosis, Adult ; Aged ; Aged, 80 and over ; Bronchoalveolar Lavage Fluid/cytology ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Neutrophils ; Predictive Value of Tests ; Pulmonary Diffusing Capacity ; Pulmonary Fibrosis/diagnostic imaging ; Pulmonary Fibrosis/physiopathology ; Residual Volume ; Scleroderma, Diffuse/diagnostic imaging ; Scleroderma, Diffuse/physiopathology ; Severity of Illness Index ; Vital Capacity |
| مستخلص: | Introduction and aim: Progressive systemic sclerosis (pSS) is a multisystemic connective tissue disease characterized by fibrosis of the skin and internal organs including lung. The mechanisms that leads to progressive lung fibrosis in scleroderma remain obscure. In this study, we aimed to investigate the correlation between HRCT findings and patients' clinical and functional status and the degree of alveolitis based on the BAL resultsMaterials and methods: 65 patients with pSS were evaluated. Thoracic HRCT, pulmonary function tests, and dyspnea measurements were applied, and BAL was performed. The parenchymal abnormalities identified on HRCT were coded, and scored according to Warrick et al. Results: Among parameters investigated, a correlation was found between the number of segments with subpleural cysts and the duration of disease. Also there was a correlation between the HRCT score and patient age whereas no correlation was detected between the duration of the disease, manifestation of the symptoms, and the x-ray findings. A correlation was found between the percentage of neutrophils detected in BAL and the extent of the honeycombing on HRCT. Conclusion: This study showed a strong correlation between the extent of x-ray abnormalities and FVC, RV, and DLCO, as well as an increase in the percentage of BAL fluid neutrophils in patients with SSc-PI. |
| فهرسة مساهمة: | Keywords: Scleroderma, High Resolution Computed Tomography, Pulmonary Function Test |
| تواريخ الأحداث: | Date Created: 20170113 Date Completed: 20170626 Latest Revision: 20170626 |
| رمز التحديث: | 20231215 |
| PMID: | 28079847 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2532-179X |
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