دورية أكاديمية
أعرض في EDS

Serum serotonin, leptin, and adiponectin changes in women with postpartum depression: controlled study.

التفاصيل البيبلوغرافية
العنوان: Serum serotonin, leptin, and adiponectin changes in women with postpartum depression: controlled study.
المؤلفون: Yildiz G; Department of Obstetrics and Gynecology, Muş Şifa Private Hospital, Kültür district, 168 th street, Muş, Turkey., Senturk MB; Department of Obstetrics and Gynecology, Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, Opr. Dr. Burhanettin Ustunel street, No: 10, 34668, Uskudar, Istanbul, Turkey. dr.baki77@gmail.com., Yildiz P; Department of Obstetrics and Gynecology, Muş Şifa Private Hospital, Kültür district, 168 th street, Muş, Turkey., Cakmak Y; Department of Obstetrics and Gynecology, Batman State Hospital, Ziya Gokalp district, 72060, Batman, Turkey., Budak MS; Department of Obstetrics and Gynecology, Diyarbakir Women and Child Hospital, Bagcılar district, 21060, Baglar, Diyarbakir, Turkey., Cakar E; Department of Obstetrics and Gynecology, Zeynep Kamil Gynecologic and Pediatric Training and Research Hospital, Opr. Dr. Burhanettin Ustunel street, No: 10, 34668, Uskudar, Istanbul, Turkey.
المصدر: Archives of gynecology and obstetrics [Arch Gynecol Obstet] 2017 Apr; Vol. 295 (4), pp. 853-858. Date of Electronic Publication: 2017 Feb 21.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8710213 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0711 (Electronic) Linking ISSN: 09320067 NLM ISO Abbreviation: Arch Gynecol Obstet Subsets: MEDLINE
أسماء مطبوعة: Publication: Berlin : Springer Verlag
Original Publication: München : Springer International, c1987-
مواضيع طبية MeSH: Adiponectin/*blood , Depression, Postpartum/*blood , Leptin/*blood , Serotonin/*blood, Adult ; Depression, Postpartum/etiology ; Female ; Humans ; Mothers ; Postpartum Period/blood
مستخلص: Purpose: Postpartum depression (PPD) affects nearly 10% of mothers after delivery and has many serious results. Although many factors associated with PPD, the etiology, and pathophysiology of PPD are not known completely. The relationship between serum serotonin concentration and depression is well known, but there are no enough data regarding the serum change of leptin and adiponectin. The aims of this study are to research the level of serum serotonin, leptin,s and adiponectin concentrations in women with PPD.
Materials and Methods: A controlled trial has been conducted in three centers. Two hundred and forty four women were evaluated at postpartum day 10 with the Edinburgh Postnatal Depression Scale (EPDD). Venous blood samples were collected and serotonin, and leptin and adiponectin levels were studied using human enzyme-linked immunosorbent assay. Mann-Whitney U test was used for comparison of serum levels of serotonin, leptin, and adiponectin between women with PPD and without. A p value of <0.05 was considered significant.
Results: PPD was detected in 70 postpartum women. The mean serum serotonin level was significantly lower in the group with PPD (p = 0.001), while mean serum adiponectin level was higher (p = 0.001). The mean serum leptin level was not different (p = 0.133).
Conclusions: The serum adiponectin and leptin levels were high in women with PPD. This could play important role in the pathophysiology of PPD. Elevation of serum levels also may play antidepressant role against PPD, especially the early postpartum period.
فهرسة مساهمة: Keywords: Adiponectin; Leptin; Postpartum; Postpartum depression
المشرفين على المادة: 0 (ADIPOQ protein, human)
0 (Adiponectin)
0 (Leptin)
333DO1RDJY (Serotonin)
تواريخ الأحداث: Date Created: 20170223 Date Completed: 20170911 Latest Revision: 20220330
رمز التحديث: 20240628
DOI: 10.1007/s00404-017-4313-0
PMID: 28224268
قاعدة البيانات: MEDLINE
الوصف
تدمد:1432-0711
DOI:10.1007/s00404-017-4313-0