دورية أكاديمية
Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals.
| العنوان: | Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals. |
|---|---|
| المؤلفون: | Mohorianu I; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom., Bretman A; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom.; School of Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom., Smith DT; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom., Fowler EK; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom., Dalmay T; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom., Chapman T; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, United Kingdom. |
| المصدر: | RNA (New York, N.Y.) [RNA] 2017 Jul; Vol. 23 (7), pp. 1048-1059. Date of Electronic Publication: 2017 Apr 20. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-9001 (Electronic) Linking ISSN: 13558382 NLM ISO Abbreviation: RNA Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2003->: Cold Spring Harbor, NY : Cold Spring Harbor Laboratory Press Original Publication: New York, NY : Cambridge University Press, c1995- |
| مواضيع طبية MeSH: | Competitive Behavior/*physiology , Drosophila Proteins/*genetics , Drosophila melanogaster/*genetics , Genomics/*methods , Sexual Behavior, Animal/*physiology, Animals ; Drosophila melanogaster/physiology ; Gene Expression Profiling/methods ; Gene Expression Regulation ; Gene Regulatory Networks ; Male ; Sequence Analysis, RNA/methods |
| مستخلص: | Socio-sexual environments have profound effects on fitness. Local sex ratios can alter the threat of sexual competition, to which males respond via plasticity in reproductive behaviors and ejaculate composition. In Drosophila melanogaster , males detect the presence of conspecific, same-sex mating rivals prior to mating using multiple, redundant sensory cues. Males that respond to rivals gain significant fitness benefits by altering mating duration and ejaculate composition. Here we investigated the underlying genome-wide changes involved. We used RNA-seq to analyze male transcriptomic responses 2, 26, and 50 h after exposure to rivals, a time period that was previously identified as encompassing the major facets of male responses to rivals. The results showed a strong early activation of multiple sensory genes in the head-thorax (HT), prior to the expression of any phenotypic differences. This gene expression response was reduced by 26 h, at the time of maximum phenotypic change, and shut off by 50 h. In the abdomen (A), fewer genes changed in expression and gene expression responses appeared to increase over time. The results also suggested that different sets of functionally equivalent genes might be activated in different replicates. This could represent a mechanism by which robustness is conferred upon highly plastic traits. Overall, our study reveals that mRNA-seq can identify subtle genomic signatures characteristic of flexible behavioral phenotypes. (© 2017 Mohorianu et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.) |
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| معلومات مُعتمدة: | BB/L003139/1 United Kingdom Biotechnology and Biological Sciences Research Council; BB/H002499/1 United Kingdom Biotechnology and Biological Sciences Research Council |
| فهرسة مساهمة: | Keywords: RNA-seq; sexual selection; sperm competition; subsampling normalization |
| المشرفين على المادة: | 0 (Drosophila Proteins) |
| تواريخ الأحداث: | Date Created: 20170422 Date Completed: 20170920 Latest Revision: 20181113 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC5473139 |
| DOI: | 10.1261/rna.059246.116 |
| PMID: | 28428330 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1469-9001 |
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| DOI: | 10.1261/rna.059246.116 |