دورية أكاديمية
Low serum selenium concentrations in French patients with measles.
| العنوان: | Low serum selenium concentrations in French patients with measles. |
|---|---|
| المؤلفون: | Garcia M; Laboratoire de virologie, CHU de Poitiers, 2, rue de la Milétrie, CS 90577, 86021 Poitiers cedex, France; UFR médecine et pharmacie, université de Poitiers, 6, rue de la Milétrie, TSA 51115, 86073 Poitiers cedex 9, France., Pineau A; UFR pharmacie, laboratoire de toxicologie, université de Nantes, 9, rue Bias, BP 53508, 44035 Nantes cedex 1, France., Guillard O; UFR médecine et pharmacie, université de Poitiers, 6, rue de la Milétrie, TSA 51115, 86073 Poitiers cedex 9, France., Ragot S; UFR médecine et pharmacie, université de Poitiers, 6, rue de la Milétrie, TSA 51115, 86073 Poitiers cedex 9, France; Inserm CIC 1402, 2, rue de la Milétrie, CS 90577, 86021 Poitiers cedex, France; Centre d'investigation clinique, CHU de Poitiers, 2, rue de la Milétrie, CS 90577, 86021 Poitiers cedex, France., Lévêque N; Laboratoire de virologie, CHU de Poitiers, 2, rue de la Milétrie, CS 90577, 86021 Poitiers cedex, France; UFR médecine et pharmacie, université de Poitiers, 6, rue de la Milétrie, TSA 51115, 86073 Poitiers cedex 9, France. Electronic address: nicolas.leveque@chu-poitiers.fr., Agius G; Laboratoire de virologie, CHU de Poitiers, 2, rue de la Milétrie, CS 90577, 86021 Poitiers cedex, France; UFR médecine et pharmacie, université de Poitiers, 6, rue de la Milétrie, TSA 51115, 86073 Poitiers cedex 9, France. |
| المصدر: | Current research in translational medicine [Curr Res Transl Med] 2017 Apr - Jun; Vol. 65 (2), pp. 89-91. Date of Electronic Publication: 2016 Nov 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier-Masson SAS Country of Publication: France NLM ID: 101681234 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2452-3186 (Electronic) Linking ISSN: 24523186 NLM ISO Abbreviation: Curr Res Transl Med Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: [Issy-les-Moulineaux Cedex] : Elsevier-Masson SAS, 2016- |
| مستخلص: | Objective: Selenium deficiency adversely affects the clinical outcome of measles in the tropics. In developed countries, serum selenium level has never been investigated during acute measles. The aim of this study was to determine serum selenium concentrations in French patients with acute measles and to seek correlations with clinical and virological findings. Patients and Methods: We studied serum selenium concentrations in 94 French patients with acute measles and in 99 healthy controls matched for age and sex. Results: The mean of selenium concentration was significantly lower in the patients than in the controls (46.4±14.1μg/L versus 86.5±13.9μg/L, P<0.0001). In the patients, selenium concentrations were not associated with age, sex, vaccination status, clinical signs or specific antibody responses. Selenium levels did not differ significantly between patients with uncomplicated measles (45.8±14.2μg/L) and patients with complications (52.7±13.2μg/L) (P=0.15). Conclusion: Acute measles is associated with significant reduction of selenium level that did not seem to negatively affect the course of the disease suggesting compensating mechanisms in patients from developed countries against the disease. (Copyright © 2016 Elsevier Masson SAS. All rights reserved.) |
| References: | J Trop Pediatr. 2004 Apr;50(2):78-81. (PMID: 15088795) Antioxid Redox Signal. 2012 Apr 1;16(7):705-43. (PMID: 21955027) Annu Rev Nutr. 2015;35:109-34. (PMID: 25974694) Clin Chem. 2005 Nov;51(11):2117-23. (PMID: 16123147) J Nutr. 2003 May;133(5 Suppl 1):1463S-7S. (PMID: 12730444) Lancet. 2012 Mar 31;379(9822):1256-68. (PMID: 22381456) Infection. 1988 Jul-Aug;16(4):222-4. (PMID: 3182086) Biol Trace Elem Res. 2011 Dec;143(3):1325-36. (PMID: 21318622) |
| فهرسة مساهمة: | Keywords: French patients; Measles; Selenium |
| تواريخ الأحداث: | Date Created: 20170428 Latest Revision: 20200401 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC7104300 |
| DOI: | 10.1016/j.retram.2016.10.002 |
| PMID: | 28447938 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2452-3186 |
|---|---|
| DOI: | 10.1016/j.retram.2016.10.002 |