دورية أكاديمية

Seroprevalence of Scrub Typhus, Typhus, and Spotted Fever Among Rural and Urban Populations of Northern Vietnam.

التفاصيل البيبلوغرافية
العنوان: Seroprevalence of Scrub Typhus, Typhus, and Spotted Fever Among Rural and Urban Populations of Northern Vietnam.
المؤلفون: Trung NV; National Hospital for Tropical Diseases, Hanoi, Vietnam., Hoi LT; National Hospital for Tropical Diseases, Hanoi, Vietnam., Thuong NTH; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Toan TK; Hanoi Medical University, Hanoi, Vietnam., Huong TTK; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Hoa TM; National Hospital for Tropical Diseases, Hanoi, Vietnam., Fox A; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Kinh NV; National Hospital for Tropical Diseases, Hanoi, Vietnam., van Doorn HR; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Wertheim HFL; Department of Medical Microbiology, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Bryant JE; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam., Nadjm B; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.; Oxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Hanoi, Vietnam.
المصدر: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2017 May; Vol. 96 (5), pp. 1084-1087.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: American Society of Tropical Medicine and Hygiene Country of Publication: United States NLM ID: 0370507 Publication Model: Print Cited Medium: Internet ISSN: 1476-1645 (Electronic) Linking ISSN: 00029637 NLM ISO Abbreviation: Am J Trop Med Hyg Subsets: MEDLINE
أسماء مطبوعة: Publication: Northbrook, IL : American Society of Tropical Medicine and Hygiene
Original Publication: Baltimore.
مواضيع طبية MeSH: Antibodies, Bacterial/*blood , Rickettsia Infections/*epidemiology , Scrub Typhus/*epidemiology , Typhus, Epidemic Louse-Borne/*epidemiology, Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Male ; Orientia tsutsugamushi/classification ; Orientia tsutsugamushi/isolation & purification ; Prevalence ; Rickettsia/classification ; Rickettsia/isolation & purification ; Rickettsia Infections/blood ; Rickettsia Infections/diagnosis ; Rickettsia prowazekii/classification ; Rickettsia prowazekii/isolation & purification ; Rural Population ; Scrub Typhus/blood ; Scrub Typhus/diagnosis ; Seroepidemiologic Studies ; Serotyping ; Typhus, Epidemic Louse-Borne/blood ; Typhus, Epidemic Louse-Borne/diagnosis ; Urban Population ; Vietnam/epidemiology
مستخلص: AbstractRickettsial infections are recognized as important causes of fever throughout southeast Asia. Herein, we determined the seroprevalence to rickettsioses within rural and urban populations of northern Vietnam. Prevalence of individuals with evidence of prior rickettsial infections (IgG positive) was surprisingly low, with 9.14% (83/908) testing positive to the three major rickettsial serogroups thought to circulate in the region. Prevalence of typhus group rickettsiae (TG)-specific antibodies (6.5%, 58/908) was significantly greater than scrub typhus group orientiae (STG)- or spotted fever group rickettsiae (SFG)-specific antibodies ( P < 0.05). The majority of TG seropositives were observed among urban rather than rural residents ( P < 0.05). In contrast, overall antibody prevalence to STG and SFG were both very low (1.1%, 10/908 for STG; 1.7%, 15/908 for SFG), with no significant differences between rural and urban residents. These results provide data on baseline population characteristics that may help inform development of Rickettsia serological testing criteria in future clinical studies.
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معلومات مُعتمدة: United Kingdom WT_ Wellcome Trust
المشرفين على المادة: 0 (Antibodies, Bacterial)
تواريخ الأحداث: Date Created: 20170514 Date Completed: 20170803 Latest Revision: 20240716
رمز التحديث: 20240716
مُعرف محوري في PubMed: PMC5417199
DOI: 10.4269/ajtmh.16-0399
PMID: 28500808
قاعدة البيانات: MEDLINE
الوصف
تدمد:1476-1645
DOI:10.4269/ajtmh.16-0399