دورية أكاديمية
أعرض في EDS

Rapid rest/stress regadenoson ungated perfusion CMR for detection of coronary artery disease in patients with atrial fibrillation.

التفاصيل البيبلوغرافية
العنوان: Rapid rest/stress regadenoson ungated perfusion CMR for detection of coronary artery disease in patients with atrial fibrillation.
المؤلفون: Bieging ET; Division of Cardiovascular Medicine, University of Utah, 50 N Medical Dr, Salt Lake City, UT, 84132, USA. erik.bieging@hsc.utah.edu., Haider I; Division of Cardiovascular Medicine, University of Utah, 50 N Medical Dr, Salt Lake City, UT, 84132, USA., Adluru G; Department of Radiology and Imaging Sciences, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT, 84108, USA., Chang L; Division of Cardiovascular Medicine, University of Utah, 50 N Medical Dr, Salt Lake City, UT, 84132, USA., Suksaranjit P; Division of Cardiovascular Medicine, University of Utah, 50 N Medical Dr, Salt Lake City, UT, 84132, USA., Likhite D; Department of Radiology and Imaging Sciences, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT, 84108, USA., Shaaban A; Department of Radiology and Imaging Sciences, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT, 84108, USA., Jensen L; Department of Radiology and Imaging Sciences, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT, 84108, USA., Wilson BD; Division of Cardiovascular Medicine, University of Utah, 50 N Medical Dr, Salt Lake City, UT, 84132, USA., McGann CJ; Department of Cardiology, Swedish Medical Center, 550 17th Ave, Seattle, WA, 98122, USA., DiBella E; Department of Radiology and Imaging Sciences, Utah Center for Advanced Imaging Research, University of Utah, 729 Arapeen Drive, Salt Lake City, UT, 84108, USA.
المصدر: The international journal of cardiovascular imaging [Int J Cardiovasc Imaging] 2017 Nov; Vol. 33 (11), pp. 1781-1788. Date of Electronic Publication: 2017 May 20.
نوع المنشور: Comparative Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE
أسماء مطبوعة: Publication: [New York] : Springer
Original Publication: Boston : Kluwer Academic Publishers, c2001-
مواضيع طبية MeSH: Coronary Circulation* , Heart Rate*, Atrial Fibrillation/*complications , Coronary Artery Disease/*diagnostic imaging , Magnetic Resonance Imaging/*methods , Myocardial Perfusion Imaging/*methods , Purines/*administration & dosage , Pyrazoles/*administration & dosage , Vasodilator Agents/*administration & dosage, Aged ; Aged, 80 and over ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/physiopathology ; Coronary Angiography ; Coronary Artery Disease/complications ; Coronary Artery Disease/physiopathology ; Female ; Humans ; Hyperemia/physiopathology ; Male ; Middle Aged ; Predictive Value of Tests ; Reproducibility of Results ; Time Factors
مستخلص: Cardiovascular magnetic resonance (CMR) perfusion has been established as a useful imaging modality for the detection of coronary artery disease (CAD). However, there are several limitations when applying standard, ECG-gated stress/rest perfusion CMR to patients with atrial fibrillation (AF). In this study we investigate an approach with no ECG gating and a rapid rest/stress perfusion protocol to determine its accuracy for detection of CAD in patients with AF. 26 patients with AF underwent a rapid rest/regadenoson stress CMR perfusion imaging protocol, and all patients had X-ray coronary angiography. An ungated radial myocardial perfusion sequence was used. Imaging protocol included: rest perfusion image acquisition, followed nearly immediately by administration of regadenoson to induce hyperemia, 60 s wait, and stress image acquisition. CMR perfusion images were interpreted by three blinded readers as normal or abnormal. Diagnostic accuracy was evaluated by comparison to X-ray angiography. 21 of the CMR rest/stress perfusion scans were negative, and 5 were positive by angiography criteria. Majority results of the ungated datasets from all of the readers showed a sensitivity, specificity and accuracy of 80, 100 and 96%, respectively, for detection of CAD. An ungated, rapid rest/stress regadenoson perfusion CMR protocol appears to be useful for the diagnosis of obstructive CAD in patients with AF.
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معلومات مُعتمدة: R01 HL113224 United States HL NHLBI NIH HHS
فهرسة مساهمة: Keywords: Atrial fibrillation; Cardiac perfusion; ECG gating; Myocardial perfusion imaging; Ungated cardiac MR
سلسلة جزيئية: ClinicalTrials.gov NCT01710254
المشرفين على المادة: 0 (Purines)
0 (Pyrazoles)
0 (Vasodilator Agents)
2XLN4Y044H (regadenoson)
تواريخ الأحداث: Date Created: 20170522 Date Completed: 20180105 Latest Revision: 20181201
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC6267777
DOI: 10.1007/s10554-017-1168-1
PMID: 28528431
قاعدة البيانات: MEDLINE
الوصف
تدمد:1875-8312
DOI:10.1007/s10554-017-1168-1