دورية أكاديمية
أعرض في EDS

Evaluation of intraretinal migration of retinal pigment epithelial cells in age-related macular degeneration using polarimetric imaging.

التفاصيل البيبلوغرافية
العنوان: Evaluation of intraretinal migration of retinal pigment epithelial cells in age-related macular degeneration using polarimetric imaging.
المؤلفون: Miura M; Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Ami, Japan. m-miura@tokyo-med.ac.jp.; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan. m-miura@tokyo-med.ac.jp., Makita S; Computational Optics Group, University of Tsukuba, Tsukuba, Japan., Sugiyama S; Computational Optics Group, University of Tsukuba, Tsukuba, Japan.; Tomey Corporation, Nagoya, Aichi, Japan., Hong YJ; Computational Optics Group, University of Tsukuba, Tsukuba, Japan., Yasuno Y; Computational Optics Group, University of Tsukuba, Tsukuba, Japan., Elsner AE; School of Optometry, Indiana University, Bloomington, IN, USA., Tamiya S; Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA., Tsukahara R; Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Ami, Japan.; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan., Iwasaki T; Department of Ophthalmology, Tokyo Medical University, Ibaraki Medical Center, Ami, Japan.; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan., Goto H; Department of Ophthalmology, Tokyo Medical University, Tokyo, Japan.
المصدر: Scientific reports [Sci Rep] 2017 Jun 09; Vol. 7 (1), pp. 3150. Date of Electronic Publication: 2017 Jun 09.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Epithelial Cells/*pathology , Macular Degeneration/*diagnostic imaging , Retinal Detachment/*diagnostic imaging , Retinal Drusen/*diagnostic imaging , Retinal Pigment Epithelium/*diagnostic imaging , Scanning Laser Polarimetry/*methods, Aged ; Aged, 80 and over ; Cell Movement ; Disease Progression ; Female ; Humans ; Macular Degeneration/classification ; Macular Degeneration/pathology ; Male ; Middle Aged ; Ophthalmoscopy/methods ; Optical Imaging/methods ; Prospective Studies ; Retinal Detachment/classification ; Retinal Detachment/pathology ; Retinal Drusen/classification ; Retinal Drusen/pathology ; Retinal Pigment Epithelium/pathology ; Scanning Laser Polarimetry/instrumentation ; Tomography, Optical Coherence/methods
مستخلص: The purpose of the present study was to evaluate the intraretinal migration of the retinal pigment epithelium (RPE) cells in age-related macular degeneration (AMD) using polarimetry. We evaluated 155 eyes at various AMD stages. Depolarized light images were computed using a polarization-sensitive scanning laser ophthalmoscope (PS-SLO), and the degree of polarization uniformity was calculated using polarization-sensitive optical coherence tomography (OCT). Each polarimetry image was compared with the corresponding autofluorescence (AF) images at 488 nm (SW-AF) and at 787 nm (NIR-AF). Intraretinal RPE migration was defined by the presence of depolarization at intraretinal hyperreflective foci on PS-SLO and PS-OCT images, and by the presence of hyper-AF on both NIR-AF and SW-AF images. RPE migration was detected in 52 of 155 eyes (33.5%) and was observed in drusenoid pigment epithelial detachment (PED) and serous PED with significantly higher frequencies than in other groups (P = 0.015). The volume of the migrated RPE cluster in serous PED was significantly correlated with the volume of the PED (R 2  = 0.26; P = 0.011). Overall, our results showed that intraretinal RPE migrations occurred in various AMD stages, and that they occurred more commonly in eyes with serous and drusenoid PED.
References: Invest Ophthalmol Vis Sci. 2012 Jul 09;53(8):4626-33. (PMID: 22589439)
Neuroimage. 1994 Nov;1(4):325-33. (PMID: 9343582)
Am J Ophthalmol. 2001 Nov;132(5):668-81. (PMID: 11704028)
Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7462-72. (PMID: 26595606)
Eye (Lond). 1995;9 ( Pt 6):763-71. (PMID: 8849547)
Am J Ophthalmol. 2002 Sep;134(3):411-31. (PMID: 12208254)
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1468-80. (PMID: 17429494)
J Biomed Opt. 2010 Nov-Dec;15(6):061704. (PMID: 21198152)
Ophthalmology. 2013 Dec;120(12):2656-65. (PMID: 23830761)
Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6448-55. (PMID: 26444725)
Prog Retin Eye Res. 2014 Jul;41:64-89. (PMID: 24704580)
Ophthalmology. 2013 Apr;120(4):821-8. (PMID: 23357621)
Prog Retin Eye Res. 2011 Nov;30(6):431-51. (PMID: 21729763)
Opt Lett. 2014 Dec 15;39(24):6783-6. (PMID: 25502996)
Graefes Arch Clin Exp Ophthalmol. 2014 Sep;252(9):1413-21. (PMID: 24577742)
Retina. 2013 Feb;33(2):265-76. (PMID: 23266879)
Am J Ophthalmol. 2015 Aug;160(2):335-344.e1. (PMID: 25982973)
Ophthalmology. 1985 May;92(5):615-27. (PMID: 2409504)
Biomed Opt Express. 2015 Nov 19;6(12):4951-74. (PMID: 26713208)
Invest Ophthalmol Vis Sci. 2016 Oct 1;57(13):5479-5489. (PMID: 27760262)
Exp Eye Res. 2016 Jan;142:26-31. (PMID: 26675400)
Eye (Lond). 1988;2 ( Pt 5):552-77. (PMID: 2476333)
Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2661-7. (PMID: 18515594)
Invest Ophthalmol Vis Sci. 2006 Dec;47(12):5487-94. (PMID: 17122140)
Invest Ophthalmol Vis Sci. 2015 May;56(5):3253-68. (PMID: 25813989)
Invest Ophthalmol Vis Sci. 2008 Sep;49(9):4137-44. (PMID: 18487363)
Clin Ophthalmol. 2014 Feb 24;8:435-40. (PMID: 24591813)
Biomed Opt Express. 2012 Jul 1;3(7):1670-83. (PMID: 22808437)
Retina. 2012 Jan;32(1):77-85. (PMID: 21866075)
Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3556-64. (PMID: 16877429)
Invest Ophthalmol Vis Sci. 1995 Mar;36(3):718-29. (PMID: 7890502)
Retina. 2011 Mar;31(3):453-63. (PMID: 21221050)
Opt Express. 2013 Aug 12;21(16):19412-36. (PMID: 23938857)
Exp Eye Res. 2014 Sep;126:61-7. (PMID: 25152361)
Invest Ophthalmol Vis Sci. 2014 Mar 13;55(3):1564-71. (PMID: 24526446)
Ophthalmology. 2013 May;120(5):1038-45. (PMID: 23352193)
Invest Ophthalmol Vis Sci. 2014 Jul 22;55(8):5016-31. (PMID: 25052993)
Invest Ophthalmol Vis Sci. 2013 Dec 13;54(14):ORSF5-ORSF13. (PMID: 24335069)
Invest Ophthalmol Vis Sci. 2015 May;56(5):3269-78. (PMID: 26024109)
Graefes Arch Clin Exp Ophthalmol. 2012 Aug;250(8):1129-36. (PMID: 22290070)
Br J Ophthalmol. 2011 Aug;95(8):1134-9. (PMID: 20881028)
Ophthalmology. 2009 May;116(5):914-20. (PMID: 19410950)
Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5965-9. (PMID: 20574019)
Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4061-8. (PMID: 12939329)
Mol Vis. 2011;17 :1222-30. (PMID: 21617757)
Nat Methods. 2012 Jun 28;9(7):676-82. (PMID: 22743772)
Ophthalmology. 2009 Mar;116(3):488-496.e2. (PMID: 19167082)
Br J Ophthalmol. 2006 Feb;90(2):191-7. (PMID: 16424532)
Am J Ophthalmol. 2013 Jan;155(1):1-35.e13. (PMID: 23245386)
PLoS One. 2016 Oct 6;11(10 ):e0164419. (PMID: 27711217)
Invest Ophthalmol Vis Sci. 2002 Aug;43(8):2749-57. (PMID: 12147612)
N Engl J Med. 2006 Oct 5;355(14):1474-85. (PMID: 17021323)
Ophthalmology. 2015 Nov;122(11):2316-26. (PMID: 26298717)
Opt Express. 2008 Oct 13;16(21):16410-22. (PMID: 18852747)
Retina. 2014 Apr;34(4):732-40. (PMID: 24177189)
Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4324-32. (PMID: 11095634)
Opt Lett. 2012 Jun 1;37(11):1958-60. (PMID: 22660086)
Retina. 2008 Jan;28(1):5-35. (PMID: 18185134)
Am J Ophthalmol. 2005 Dec;140(6):1014-1019. (PMID: 16376644)
Ophthalmology. 2011 Apr;118(4):687-93. (PMID: 21093923)
Am J Ophthalmol. 2016 Apr;164:89-98. (PMID: 26868959)
J Opt Soc Am A Opt Image Sci Vis. 2007 May;24(5):1431-7. (PMID: 17429490)
J Biomed Opt. 2006 May-Jun;11(3):34010. (PMID: 16822060)
معلومات مُعتمدة: R41 EY026105 United States EY NEI NIH HHS; R44 EY024186 United States EY NEI NIH HHS
تواريخ الأحداث: Date Created: 20170611 Date Completed: 20181228 Latest Revision: 20201120
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC5466639
DOI: 10.1038/s41598-017-03529-8
PMID: 28600515
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-017-03529-8