دورية أكاديمية
Early Empiric Antibiotic Use Is Associated With Delayed Feeding Tolerance in Preterm Infants: A Retrospective Analysis.
| العنوان: | Early Empiric Antibiotic Use Is Associated With Delayed Feeding Tolerance in Preterm Infants: A Retrospective Analysis. |
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| المؤلفون: | Martinez FE; Faculty of Medicine Ribeirão Preto-Universidade de São Paulo †Faculty of Medicine São Paulo-Universidade de São Paulo, São Paulo ‡Escola Paulista de Medicina, Universidade Federal de São Paulo §Instituto de Medicina Integral Prof Fernando Figueira-IMIP, Recife ||Hospital Universitário da Universidade Federal do Maranhão, São Luís ¶Faculdade de Ciencias Médicas-UNICAMP, São Paulo #Faculdade de Medicina de Botucatu-UNESP, Botucatu **Instituto Fernandes Figueira-FIOCRUZ, Rio de Janeiro ††Faculdade de Medicina da PUC Porto Alegre ‡‡Universidade Federal do Rio Grande do Sul, Porto Alegre §§Universidade Estadual do Rio de Janeiro, Rio de Janeiro ||||Universidade Federal de Minas Gerais, Belo Horizonte ¶¶Universidade Federal de Uberlândia, Uberlândia ##Faculdade de Ciências Médicas de Minas Gerais, Belo Horizonte ***Hospital Universitário da Universidade de São Paulo, São Paulo †††Hospital Estadual Sumaré, Sumaré ‡‡‡Hospital Geral de Pirajussara, Taboão da Serra §§§Hospital Estadual de Diadema, Diadema ||||||Universidade Estadual de Londrina, Londrina ¶¶¶Universidade Federal do Paraná, Curitiba, Brazil ###University of Toronto, Toronto, Canada., Ferri WAG, Leone CR, de Almeida MFB, Guinsburg R, Meneses JDA, Vale MSD, Marba STM, de Carvalho WB, de Souza Rugolo LMS, de Andrade Lopes JM, Ribeiro MA, Procianoy RS, Duarte JLMB, Bouzada MCF, de Lima Mota Ferreira DM, Filho NA, de Albuquerque Diniz EM, Zanardi DMT, Testoni D, Santos CND, Gomzález MRC, Venzon PS, Belik J |
| مؤلفون مشاركون: | for Brazilian Neonatal Research Network |
| المصدر: | Journal of pediatric gastroenterology and nutrition [J Pediatr Gastroenterol Nutr] 2017 Jul; Vol. 65 (1), pp. 107-110. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 8211545 Publication Model: Print Cited Medium: Internet ISSN: 1536-4801 (Electronic) Linking ISSN: 02772116 NLM ISO Abbreviation: J Pediatr Gastroenterol Nutr Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2024- : [Hoboken, New Jersey] : Wiley Original Publication: [New York, N.Y.] : Raven Press, [c1982- |
| مواضيع طبية MeSH: | Anti-Bacterial Agents/*adverse effects , Enteral Nutrition/*statistics & numerical data , Enterocolitis, Necrotizing/*chemically induced , Feeding and Eating Disorders/*chemically induced , Infant, Premature, Diseases/*chemically induced , Parenteral Nutrition, Total/*statistics & numerical data, Enterocolitis, Necrotizing/epidemiology ; Feeding and Eating Disorders/epidemiology ; Female ; Humans ; Infant, Newborn ; Infant, Premature ; Infant, Premature, Diseases/epidemiology ; Male ; Outcome Assessment, Health Care ; Prevalence ; Retrospective Studies |
| مستخلص: | The causative factors of neonatal feeding intolerance are poorly understood, but potentially related to clinical practices such as empiric antibiotic usage. The objective of this study was to evaluate whether early empiric antibiotic exposure negatively affects preterm infants' enteral feeding tolerance. Data from infants without risk factors for sepsis, 500 to 1499 g birth weight and 24 to 34 weeks gestational age were analyzed. The primary outcomes were the empiric antibiotic exposure effects on the infants' total parenteral nutrition usage duration and prevalence of necrotizing enterocolitis (NEC). Among the 901 infants included, 67 were exposed to early empiric antibiotic. A 50% increase in parenteral nutrition usage duration and a 4-fold greater prevalence of NEC was seen in the early empiric antibiotic-exposed neonates, when compared with control infants (P < 0.01). Early empiric antibiotic exposure appears to negatively influence preterm infant feeding tolerance and possibly contributes to NEC. |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20170624 Date Completed: 20180321 Latest Revision: 20191210 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1097/MPG.0000000000001490 |
| PMID: | 28644358 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1536-4801 |
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| DOI: | 10.1097/MPG.0000000000001490 |