دورية أكاديمية
أعرض في EDS

Antimicrobial stewardship in the treatment of skin and soft tissue infections.

التفاصيل البيبلوغرافية
العنوان: Antimicrobial stewardship in the treatment of skin and soft tissue infections.
المؤلفون: Gibbons JA; UnityPoint Health-Des Moines, Des Moines, IA., Smith HL; UnityPoint Health-Des Moines, Des Moines, IA. Electronic address: hayden.smith@unitypoint.org., Kumar SC; UnityPoint Health-Des Moines, Des Moines, IA., Duggins KJ; Bryan Health, Lincoln, NE., Bushman AM; UnityPoint Health-Des Moines, Des Moines, IA., Danielson JM; Douglas County Hospital, Alexandria, MN., Yost WJ; UnityPoint Health-Des Moines, Des Moines, IA., Wadle JJ; Des Moines University, Des Moines, IA.
المصدر: American journal of infection control [Am J Infect Control] 2017 Nov 01; Vol. 45 (11), pp. 1203-1207. Date of Electronic Publication: 2017 Jul 18.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 8004854 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3296 (Electronic) Linking ISSN: 01966553 NLM ISO Abbreviation: Am J Infect Control Subsets: MEDLINE
أسماء مطبوعة: Original Publication: St. Louis, Mosby
مواضيع طبية MeSH: Antimicrobial Stewardship*/methods, Anti-Infective Agents/*therapeutic use , Skin Diseases, Infectious/*drug therapy , Soft Tissue Infections/*drug therapy, Administration, Intravenous ; Administration, Oral ; Aged ; Anti-Infective Agents/administration & dosage ; Female ; Humans ; Inappropriate Prescribing/prevention & control ; Inappropriate Prescribing/statistics & numerical data ; Male ; Middle Aged ; Treatment Outcome
مستخلص: Background: Research on treating skin and soft tissue infections (SSTI) has shown improved patient outcomes with effective pharmaceutic prescribing. Antimicrobial stewardship programs can reduce consequences of broad-spectrum antimicrobial administration in SSTI treatment.
Methods: Prospective and historic control data were collected during two 7-month periods. Intervention consisted of implementing a new SSTI evidence-based treatment algorithm and provider education, including calls and medical record notes targeted at physicians.
Results: Of 412 patients, 76 and 86 were found eligible from the historic and intervention groups, respectively. The intervention group had a higher prevalence of appropriate antibiotic usage (33% vs 19%, respectively; P = .04). There was a lower median number of days from intravenous antibiotic therapy to oral conversion (3 vs 5; P < .0001) and a lower median number of days of antipseudomonal antibiotic use (3 vs 5; P = .03) in the intervention group, respectively. The intervention group also had fewer documented SSTI treatment complications (1% vs 8%, respectively; P = .04). The positive outcomes outlined demonstrate potential impacts made from the use of multidisciplinary antibiotic stewardship initiatives.
Conclusions: Appropriate use of antimicrobial agents under the direction of an antimicrobial stewardship program can lead to improved outcomes for patients being treated for SSTIs.
(Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Antibiotic; Antimicrobial; Cellulitis; Infection; Skin; Stewardship
المشرفين على المادة: 0 (Anti-Infective Agents)
تواريخ الأحداث: Date Created: 20170723 Date Completed: 20180521 Latest Revision: 20220408
رمز التحديث: 20231215
DOI: 10.1016/j.ajic.2017.05.013
PMID: 28732743
قاعدة البيانات: MEDLINE
الوصف
تدمد:1527-3296
DOI:10.1016/j.ajic.2017.05.013