دورية أكاديمية

Quality-of-Life Outcomes Improve with Nipple-Sparing Mastectomy and Breast Reconstruction.

التفاصيل البيبلوغرافية
العنوان: Quality-of-Life Outcomes Improve with Nipple-Sparing Mastectomy and Breast Reconstruction.
المؤلفون: Bailey CR; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Ogbuagu O; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Baltodano PA; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Simjee UF; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Manahan MA; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Cooney DS; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Jacobs LK; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Tsangaris TN; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Cooney CM; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital., Rosson GD; Baltimore, Md.; Albany, N.Y.; and Philadelphia, Pa.; From the Departments of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine; the Department of Plastic Surgery, Albany Medical Center; and the Department of Surgery, Thomas Jefferson University Hospital.
المصدر: Plastic and reconstructive surgery [Plast Reconstr Surg] 2017 Aug; Vol. 140 (2), pp. 219-226.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 1306050 Publication Model: Print Cited Medium: Internet ISSN: 1529-4242 (Electronic) Linking ISSN: 00321052 NLM ISO Abbreviation: Plast Reconstr Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: : Hagerstown, MD : Lippincott Williams & Wilkins
Original Publication: Baltimore : Williams & Wilkins,
مواضيع طبية MeSH: Mammaplasty* , Nipples* , Organ Sparing Treatments* , Quality of Life*, Mastectomy/*methods, Adult ; Aged ; Humans ; Middle Aged ; Postoperative Complications/epidemiology ; Quality Improvement ; Retrospective Studies ; Treatment Outcome
مستخلص: Background: Loss of the nipple-areola complex can be psychologically and sexually devastating. Nipple-sparing mastectomy provides robust cosmetic results, but few studies have investigated the quality-of-life outcomes associated with it.
Methods: The authors performed an institutional review board-approved retrospective study of 32 patients who underwent nipple-sparing mastectomy with implant-based or autologous reconstruction and 32 control patients who underwent non-nipple-sparing mastectomy with reconstruction matched by reconstruction type and operative period. They then compared premastectomy and postreconstruction responses to the BREAST-Q, a validated and breast reconstruction-specific quality-of-life questionnaire, within and between their study and control populations.
Results: The nipple-sparing and non-nipple-sparing mastectomy groups were statistically similar in terms of mean age [49.9 ± 8.5 years (range, 36 to 69 years) and 47.7 ± 10.3 years (range, 26 to 68 years) (p = 0.29), respectively] and mean body mass index [24.3 ± 3.5 kg/m (range, 17.9 to 33.7 kg/m) and 25.5 ± 5.4 kg/m (range, 19.2 to 39.2 kg/m) (p = 0.29), respectively]. There were no significant between-group differences in occurrence of postreconstruction complications. The authors found significantly higher mean postreconstruction scores in the nipple-sparing mastectomy group within the Satisfaction with Breasts (p = 0.039) and the Satisfaction with Outcome (p = 0.017) domains. Finally, they noted higher median postreconstruction scores in the nipple-sparing mastectomy group within the Psychosocial Well-being (p = 0.043) and Satisfaction with Breasts (p = 0.004) domains.
Conclusions: Psychological concerns regarding malignancy may negatively impact premastectomy patient quality of life. Reconstructive surgery improves patients' postmastectomy quality of life. Nipple-sparing mastectomy appears to provide significantly better improvement in postreconstruction quality of life, specifically in the Satisfaction with Breasts and Satisfaction with Outcome domains of the BREAST-Q, compared with non-nipple-sparing mastectomies.
Clinical Question/level of Evidence: Therapeutic, III.
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تواريخ الأحداث: Date Created: 20170727 Date Completed: 20170907 Latest Revision: 20220409
رمز التحديث: 20221213
DOI: 10.1097/PRS.0000000000003505
PMID: 28746266
قاعدة البيانات: MEDLINE
الوصف
تدمد:1529-4242
DOI:10.1097/PRS.0000000000003505