دورية أكاديمية
أعرض في EDS

A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation.

التفاصيل البيبلوغرافية
العنوان: A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation.
المؤلفون: Hajny S; Department of Clinical Biochemistry, University Hospital of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. stefan.hajny.01@regionh.dk.; Department of Biomedical Sciences, Faculty of Health and Science, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark. stefan.hajny.01@regionh.dk., Christoffersen C; Department of Clinical Biochemistry, University Hospital of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. christina.christoffersen@regionh.dk.; Department of Biomedical Sciences, Faculty of Health and Science, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen, Denmark. christina.christoffersen@regionh.dk.; Department of Cardiology, University Hospital of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. christina.christoffersen@regionh.dk.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2017 Jul 27; Vol. 18 (8). Date of Electronic Publication: 2017 Jul 27.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Signal Transduction*, Apolipoproteins M/*metabolism , Inflammation/*metabolism , Inflammation/*pathology , Liver Cirrhosis/*metabolism , Lysophospholipids/*metabolism , Nervous System/*pathology , Sphingosine/*analogs & derivatives, Animals ; Humans ; Sphingosine/metabolism
مستخلص: Hepatocytes, renal proximal tubule cells as well as the highly specialized endothelium of the blood brain barrier (BBB) express and secrete apolipoprotein M (apoM). ApoM is a typical lipocalin containing a hydrophobic binding pocket predominantly carrying Sphingosine-1-Phosphate (S1P). The small signaling molecule S1P is associated with several physiological as well as pathological pathways whereas the role of apoM is less explored. Hepatic apoM acts as a chaperone to transport S1P through the circulation and kidney derived apoM seems to play a role in S1P recovery to prevent urinal loss. Finally, polarized endothelial cells constituting the lining of the BBB express apoM and secrete the protein to the brain as well as to the blood compartment. The review will provide novel insights on apoM and S1P, and its role in hepatic fibrosis, neuroinflammation and BBB integrity.
Competing Interests: The authors declare no conflict of interest.
References: J Lipid Res. 2007 Aug;48(8):1772-80. (PMID: 17526892)
J Biol Chem. 2014 Feb 21;289(8):4683-98. (PMID: 24369175)
J Lipid Res. 2015 Jul;56(7):1271-81. (PMID: 26014962)
Mini Rev Med Chem. 2016;16(7):547-54. (PMID: 26156414)
Acta Cir Bras. 2012 Aug;27(8):589-94. (PMID: 22850713)
Arterioscler Thromb Vasc Biol. 1999 Sep;19(9):2214-25. (PMID: 10479665)
Crit Rev Biochem Mol Biol. 2015;50(4):298-313. (PMID: 25923252)
PLoS One. 2013 Oct 22;8(10):e77852. (PMID: 24167586)
Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17958-63. (PMID: 16330771)
Front Physiol. 2016 Feb 16;7:47. (PMID: 26909046)
Prostaglandins Other Lipid Mediat. 2007 Nov;84(3-4):154-62. (PMID: 17991617)
Int J Nephrol. 2012;2012:481520. (PMID: 22685655)
Crit Care Med. 2003 Apr;31(4 Suppl):S221-30. (PMID: 12682444)
FEBS J. 2013 Aug;280(16):3928-43. (PMID: 23777559)
J Biol Chem. 1998 Sep 11;273(37):23722-8. (PMID: 9726979)
J Biol Chem. 2016 Dec 30;291(53):27187-27203. (PMID: 27864331)
Cardiovasc Res. 2014 Aug 1;103(3):405-13. (PMID: 24907980)
Annu Rev Immunol. 2006;24:99-146. (PMID: 16551245)
J Neurochem. 2007 Dec;103(6):2610-9. (PMID: 17931360)
Curr Opin Lipidol. 2015 Feb;26(1):48-55. (PMID: 25551802)
Biochim Biophys Acta. 2014 May;1841(5):759-65. (PMID: 23921254)
Mol Cell Endocrinol. 2008 Feb 13;283(1-2):104-13. (PMID: 18191017)
J Mol Biol. 2010 Dec 3;404(3):363-71. (PMID: 20932978)
Hepatology. 2017 Jun;65(6):2005-2018. (PMID: 28120434)
J Hepatol. 2013 Jul;59(1):114-23. (PMID: 23466305)
J Physiol Biochem. 2016 Dec;72 (4):657-667. (PMID: 27377933)
Zhonghua Xin Xue Guan Bing Za Zhi. 2017 May 24;45(5):419-426. (PMID: 28511328)
J Lipid Res. 2004 Jul;45(7):1272-8. (PMID: 15102887)
J Neurosci. 2001 Feb 1;21(3):812-22. (PMID: 11157067)
Nat Rev Nephrol. 2016 Jun;12 (6):325-38. (PMID: 27108839)
J Lipid Res. 2016 Sep;57(9):1737-47. (PMID: 27444045)
J Exp Med. 1983 Feb 1;157(2):667-86. (PMID: 6337231)
Lipids Health Dis. 2016 Aug 30;15:142. (PMID: 27576735)
Sci Rep. 2016 Aug 01;6:30655. (PMID: 27476912)
J Am Soc Nephrol. 2014 May;25(5):1028-36. (PMID: 24357674)
Sci Signal. 2015 Aug 11;8(389):ra79. (PMID: 26268607)
Hepatology. 2006 Nov;44(5):1278-87. (PMID: 17058266)
J Lipid Res. 2014 Aug;55(8):1730-7. (PMID: 24950692)
Ann Surg. 2011 Apr;253(4):759-63. (PMID: 21475016)
Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9613-8. (PMID: 21606363)
J Mol Biol. 2009 Nov 6;393(4):920-36. (PMID: 19733574)
Biochim Biophys Acta. 2006 Dec;1758(12):2016-26. (PMID: 16996023)
Inflammation. 2015;38(3):1329-36. (PMID: 25586482)
Nat Rev Neurosci. 2006 Jan;7(1):41-53. (PMID: 16371949)
Clin Chim Acta. 2015 Jun 15;446:21-9. (PMID: 25858547)
World J Biol Chem. 2010 Oct 26;1(10):298-306. (PMID: 21537463)
J Hepatol. 2010 Oct;53(4):648-54. (PMID: 20615569)
Atherosclerosis. 2012 Mar;221(1):91-7. (PMID: 22204862)
J Am Heart Assoc. 2014 Nov 12;3(6):e001156. (PMID: 25392541)
Biochim Biophys Acta. 2008 Sep;1781(9):477-82. (PMID: 18674637)
Biochim Biophys Acta. 2006 Feb;1764(2):161-73. (PMID: 16461020)
J Neurosci. 2009 Mar 18;29(11):3579-89. (PMID: 19295162)
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17 ):4531-4536. (PMID: 28396408)
Hepatology. 2012 Oct;56(4):1427-38. (PMID: 22505286)
World J Gastroenterol. 2013 Nov 14;19(42):7341-60. (PMID: 24259965)
Blood. 1995 Jul 1;86(1):193-202. (PMID: 7795224)
Nature. 2015 Jul 16;523(7560):342-6. (PMID: 26053123)
Biochim Biophys Acta. 2012 Mar;1821(3):536-46. (PMID: 21889608)
J Biol Chem. 2015 Mar 20;290(12):7861-70. (PMID: 25627684)
J Proteome Res. 2006 Oct;5(10):2685-90. (PMID: 17022639)
Nature. 2010 Nov 11;468(7321):310-5. (PMID: 21068842)
Med Sci Monit. 2015 Jan 31;21:371-5. (PMID: 25637426)
Lipids Health Dis. 2017 Feb 8;16(1):36. (PMID: 28179022)
J Neurochem. 1994 Feb;62(2):788-98. (PMID: 8294940)
J Clin Invest. 2014 Nov;124(11):4823-8. (PMID: 25250575)
Acta Histochem. 2003;105(1):67-72. (PMID: 12666989)
Science. 2014 Jan 24;343(6169):416-9. (PMID: 24458641)
Curr Pathobiol Rep. 2014 Dec 1;2(4):143-153. (PMID: 25396098)
Science. 1984 Aug 3;225(4661):514-6. (PMID: 6429856)
J Biol Chem. 2015 Dec 25;290(52):30684-96. (PMID: 26534962)
J Biol Chem. 1999 Oct 29;274(44):31286-90. (PMID: 10531326)
Biochem J. 2000 Dec 15;352 Pt 3:809-15. (PMID: 11104690)
Proc Natl Acad Sci U S A. 1994 Oct 11;91(21):9725-9. (PMID: 7937880)
J Biol Chem. 2008 Jan 25;283(4):1839-47. (PMID: 18006500)
J Neurol Sci. 2013 May 15;328(1-2):9-18. (PMID: 23518370)
J Clin Invest. 2012 Apr;122(4):1416-26. (PMID: 22406534)
J Lipid Res. 2006 Mar;47(3):614-21. (PMID: 16371645)
Hepatol Res. 2012 Jun;42(6):543-8. (PMID: 22409274)
Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1305-15. (PMID: 27174096)
J Lipid Res. 2007 Aug;48(8):1754-62. (PMID: 17525477)
Nat Rev Mol Cell Biol. 2003 May;4(5):397-407. (PMID: 12728273)
Cell Rep. 2012 Nov 29;2(5):1104-10. (PMID: 23103166)
J Biol Chem. 2000 Jun 30;275(26):19513-20. (PMID: 10751414)
J Clin Lipidol. 2016 May-Jun;10(3):472-89. (PMID: 27206934)
CNS Drugs. 2016 Feb;30(2):135-47. (PMID: 26715391)
Acta Biochim Pol. 2011;58(3):275-85. (PMID: 21750785)
FEBS Lett. 2001 Jun 15;499(1-2):127-32. (PMID: 11418126)
Circ Res. 2010 May 28;106(10):1624-34. (PMID: 20360257)
J Biochem. 2005 Jul;138(1):47-55. (PMID: 16046448)
Hepatol Res. 2015 Nov;45(11):1136-45. (PMID: 25371278)
J Biol Chem. 2009 Aug 7;284(32):21192-200. (PMID: 19531471)
J Lipid Res. 2010 Mar;51(3):514-24. (PMID: 19767535)
PLoS One. 2017 Mar 23;12 (3):e0174424. (PMID: 28334008)
Nat Rev Cardiol. 2016 Jan;13(1):48-60. (PMID: 26323267)
Cell Mol Life Sci. 2009 Feb;66(4):559-64. (PMID: 19153651)
Arch Toxicol. 2016 May;90(5):1025-1048. (PMID: 26047667)
J Am Coll Cardiol. 2015 Sep 29;66(13):1486-8. (PMID: 26403345)
FASEB J. 2015 May;29(5):1688-700. (PMID: 25550461)
J Lipid Res. 2012 Oct;53(10):2198-204. (PMID: 22826357)
World J Gastroenterol. 2016 Dec 28;22(48):10512-10522. (PMID: 28082803)
Anal Bioanal Chem. 2015 Nov;407(28):8533-42. (PMID: 26377937)
Eur J Biochem. 1976 May 17;65(1):71-8. (PMID: 945163)
Biochim Biophys Acta. 2017 Jun;1862(6):573-588. (PMID: 28315462)
Biochem Biophys Res Commun. 2007 May 25;357(1):212-7. (PMID: 17418101)
Adv Biol Regul. 2016 Jan;60:151-159. (PMID: 26429117)
Biochemistry. 1990 Apr 24;29(16):3878-83. (PMID: 2354158)
Mediators Inflamm. 2016;2016:8606878. (PMID: 26966342)
Sci Rep. 2014 May 23;4:5051. (PMID: 24851861)
Diabetes. 2003 Dec;52(12):2989-95. (PMID: 14633861)
Lipids. 2017 Feb;52(2):109-117. (PMID: 28039587)
Cell Physiol Biochem. 2014;34(1):158-71. (PMID: 24977489)
Cell Biochem Biophys. 2004;41(3):343-56. (PMID: 15509885)
J Biol Chem. 2012 Dec 28;287(53):44645-53. (PMID: 23135269)
J Biol Chem. 1999 Oct 15;274(42):30001-7. (PMID: 10514484)
Biochem Biophys Res Commun. 2003 May 16;304(4):777-82. (PMID: 12727224)
Drug Des Devel Ther. 2015 Apr 24;9:2375-82. (PMID: 25987835)
J Biol Chem. 2008 Jul 4;283(27):18765-72. (PMID: 18460466)
JCI Insight. 2016 Dec 22;1(21):e87058. (PMID: 28018969)
FEBS Lett. 2008 Mar 5;582(5):826-8. (PMID: 18279674)
Nat Med. 2012 Jul 06;18(7):1028-40. (PMID: 22772564)
Science. 2012 Feb 17;335(6070):851-5. (PMID: 22344443)
Mol Endocrinol. 2006 Jan;20(1):212-8. (PMID: 16099815)
Lipids. 2014 Feb;49(2):183-90. (PMID: 24158769)
Br J Pharmacol. 2011 Oct;164(4):1079-106. (PMID: 21371012)
J Am Soc Nephrol. 2010 Nov;21(11):1859-67. (PMID: 20798259)
Biochim Biophys Acta. 2013 Jan;1831(1):185-92. (PMID: 22735357)
J Biol Chem. 2014 Jan 31;289(5):2801-14. (PMID: 24318881)
Int J Biol Macromol. 2007 Apr 10;40(5):484-90. (PMID: 17184834)
Atherosclerosis. 2013 Jul;229(1):102-9. (PMID: 23664237)
Annu Rev Physiol. 2017 Feb 10;79:67-91. (PMID: 27813829)
J Nutrigenet Nutrigenomics. 2016;9(5-6):306-317. (PMID: 28245483)
Trends Immunol. 2012 Dec;33(12):579-89. (PMID: 22926201)
Neurochem Int. 2001 Nov-Dec;39(5-6):415-25. (PMID: 11578777)
J Clin Invest. 1990 Nov;86(5):1641-8. (PMID: 2243137)
Arch Biochem Biophys. 2013 May;533(1-2):1-10. (PMID: 23500137)
FASEB J. 2007 Jul;21(9):2005-13. (PMID: 17341687)
Biochim Biophys Acta. 2013 Jan;1831(1):228-38. (PMID: 22801038)
Chem Biol Interact. 1999 May 14;119-120:243-9. (PMID: 10421458)
Am J Physiol. 1988 Sep;255(3 Pt 2):F520-8. (PMID: 3414808)
Pharmacol Ther. 2008 Jan;117(1):77-93. (PMID: 17961662)
Protein Pept Lett. 2010 Oct;17(10):1285-9. (PMID: 20518736)
J Neurochem. 2004 May;89(4):939-50. (PMID: 15140193)
Nat Med. 2005 Apr;11(4):418-22. (PMID: 15793583)
Clin Chim Acta. 2012 Feb 18;413(3-4):384-90. (PMID: 22115863)
Nat Med. 2013 Dec;19(12):1584-96. (PMID: 24309662)
J Invest Surg. 2004 Sep-Oct;17(5):291-4. (PMID: 15385262)
فهرسة مساهمة: Keywords: Sphingoshine-1-Phosphate; apolipoprotein M; blood brain barrier; lipid metabolism; liver fibrosis
المشرفين على المادة: 0 (Apolipoproteins M)
0 (Lysophospholipids)
26993-30-6 (sphingosine 1-phosphate)
NGZ37HRE42 (Sphingosine)
تواريخ الأحداث: Date Created: 20170728 Date Completed: 20180416 Latest Revision: 20181113
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC5578026
DOI: 10.3390/ijms18081636
PMID: 28749426
قاعدة البيانات: MEDLINE
الوصف
تدمد:1422-0067
DOI:10.3390/ijms18081636