دورية أكاديمية
Role of antimicrobial stewardship programmes in children: a systematic review.
| العنوان: | Role of antimicrobial stewardship programmes in children: a systematic review. |
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| المؤلفون: | Araujo da Silva AR; Laboratory of Teaching of Prevention and Control of Healthcare-Associated Infections, Federal Fluminense University, Rio de Janeiro, Brazil. Electronic address: andrericardo@huap.uff.br., Albernaz de Almeida Dias DC; Laboratory of Teaching of Prevention and Control of Healthcare-Associated Infections, Federal Fluminense University, Rio de Janeiro, Brazil., Marques AF; Laboratory of Teaching of Prevention and Control of Healthcare-Associated Infections, Federal Fluminense University, Rio de Janeiro, Brazil., Biscaia di Biase C; Laboratory of Teaching of Prevention and Control of Healthcare-Associated Infections, Federal Fluminense University, Rio de Janeiro, Brazil., Murni IK; Department of Paediatrics, Dr Sardjito Hospital/Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia., Dramowski A; Department of Paediatrics and Child Health, Division of Paediatric Infectious Diseases, Stellenbosch University, Stellenbosch, South Africa., Sharland M; Paediatric Infectious Diseases Research Group, St George's University, London, UK., Huebner J; Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, Ludwig-Maximilians-Universität München, Munich, Germany., Zingg W; Infection Control Programme and WHO Collaborating Centre on Patient Safety, University of Geneva Hospitals and Faculty of Medicine, Geneva, Switzerland. |
| المصدر: | The Journal of hospital infection [J Hosp Infect] 2018 Jun; Vol. 99 (2), pp. 117-123. Date of Electronic Publication: 2017 Aug 12. |
| نوع المنشور: | Journal Article; Review; Systematic Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders For The Hospital Infection Society Country of Publication: England NLM ID: 8007166 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2939 (Electronic) Linking ISSN: 01956701 NLM ISO Abbreviation: J Hosp Infect Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : W.B. Saunders For The Hospital Infection Society Original Publication: New York, Academic Press. |
| مواضيع طبية MeSH: | Antimicrobial Stewardship*, Anti-Bacterial Agents/*therapeutic use , Bacterial Infections/*drug therapy , Drug Utilization/*standards, Adolescent ; Child ; Child, Preschool ; Hospitals, Pediatric ; Humans ; Infant ; Infant, Newborn ; Organizational Policy ; Program Evaluation |
| مستخلص: | The United Nations and the World Health Organization have designated antimicrobial resistance (AMR) as a major health priority and developed action plans to reduce AMR in all healthcare settings. Establishment of institutional antimicrobial stewardship programmes (ASPs) is advocated as a key intervention to reduce antibiotic consumption in hospitals and address high rates of multi-drug-resistant (MDR) bacteria. PUBMED and the Cochrane Database of Systematic Reviews (January 2007-March 2017) were searched to identify studies reporting the effectiveness of ASPs in general paediatric wards and paediatric intensive care units (PICUs) for reducing antibiotic consumption, use of broad-spectrum/restricted antibiotics, and antibiotic resistance and healthcare-associated infections (HAIs). Neonatal units and antifungal agents were excluded. Of 2509 titles and abstracts, nine articles were eligible for inclusion in the final analysis. All studies reported a reduction in the use of broad-spectrum/restricted antibiotics or antibiotic consumption. One study reported a reduction in HAIs in a PICU, and another study evaluated bacterial resistance, showing no effect following ASP implementation. Prospective audit on antibiotic use was the most common ASP core component (eight of nine studies). Antibiotic pre-authorization was described in two studies. Other described interventions were the provision of guidelines or written information (five of nine studies), and training of healthcare professionals (one study). There is limited evidence for a reduction in antibiotic consumption and use of broad-spectrum/restricted agents following ASP implementation specifically in PICUs. Data evaluating the impact of ASPs on HAIs and AMR in PICUs are lacking. In addition, there is limited information on effective components of a successful ASP in PICUs. (Copyright © 2017 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antimicrobial stewardship programme; Children; MDRO; Multi-drug-resistant bacteria; PICU |
| المشرفين على المادة: | 0 (Anti-Bacterial Agents) |
| تواريخ الأحداث: | Date Created: 20170816 Date Completed: 20180921 Latest Revision: 20181202 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1016/j.jhin.2017.08.003 |
| PMID: | 28807835 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1532-2939 |
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| DOI: | 10.1016/j.jhin.2017.08.003 |