دورية أكاديمية
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A randomized controlled study of brief family-based intervention in obsessive compulsive disorder.

التفاصيل البيبلوغرافية
العنوان: A randomized controlled study of brief family-based intervention in obsessive compulsive disorder.
المؤلفون: Baruah U; Department of Psychiatric Social Work, National Institute of Mental Health and Neurosciences, Bangalore 560029, Karnataka, India. Electronic address: upasana.baruah@gmail.com., Pandian RD; Department of Psychiatric Social Work, National Institute of Mental Health and Neurosciences, Bangalore 560029, Karnataka, India., Narayanaswamy JC; Obsessive-Compulsive Disorder Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India., Bada Math S; Obsessive-Compulsive Disorder Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India., Kandavel T; Department of Biostatistics, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India., Reddy YCJ; Obsessive-Compulsive Disorder Clinic, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.
المصدر: Journal of affective disorders [J Affect Disord] 2018 Jan 01; Vol. 225, pp. 137-146. Date of Electronic Publication: 2017 Aug 15.
نوع المنشور: Journal Article; Randomized Controlled Trial
اللغة: English
بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Amsterdam, Elsevier/North-Holland Biomedical Press.
مواضيع طبية MeSH: Cognitive Behavioral Therapy/*methods , Family Therapy/*methods , Obsessive-Compulsive Disorder/*therapy , Selective Serotonin Reuptake Inhibitors/*therapeutic use, Adult ; Combined Modality Therapy ; Exercise Therapy/methods ; Expressed Emotion ; Female ; Humans ; Male ; Middle Aged ; Obsessive-Compulsive Disorder/psychology ; Treatment Outcome
مستخلص: Background: Cognitive behaviour therapy (CBT) for Obsessive Compulsive Disorder (OCD) is therapist-intensive and prolonged making it less accessible to patients, particularly in resource-constrained situations. We examined the efficacy of a brief psychotherapeutic intervention as an adjunct to serotonin reuptake inhibitors (SRIs) in OCD.
Method: We randomized 64 adult OCD patients stabilized on SRIs to either the 6-session brief family-based intervention (BFBI; n = 30) that included psychoeducation, exposure and response prevention and family intervention or to a control arm of relaxation exercises (RE). Assessments were conducted at baseline and at 1- and 3- months post-intervention. Primary outcome measure was response to treatment defined as ≥ 35% reduction in the Yale-Brown Obsessive Compulsive Scale total score relative to baseline score plus a Clinical Global Impression- Improvement rating of very much improved or much improved. Family accommodation and expressed emotions were also assessed.
Results: At 3- month follow-up, the BFBI group responded better than the RE group (53% vs. 12%, p < 0.001). Illness severity, family accommodation and expressed emotion declined significantly over time in the BFBI group compared to the RE group. The BFBI (OR = 13.17, p < 0.001) and baseline illness severity (OR = 0.746, p < 0.011) predicted treatment response.
Limitations: Sample size was small and follow-up duration was short. Control group had less time with the therapist although number of sessions was identical in both the groups.
Conclusion: Briefer intervention is effective in treating OCD. Briefer and inclusive format of intervention has important implications for clinical practice in resource-constrained circumstances.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
فهرسة مساهمة: Keywords: Brief intervention; Family-based; Obsessive compulsive disorder; Randomized controlled trial
المشرفين على المادة: 0 (Serotonin Uptake Inhibitors)
تواريخ الأحداث: Date Created: 20170823 Date Completed: 20180423 Latest Revision: 20221207
رمز التحديث: 20240628
DOI: 10.1016/j.jad.2017.08.014
PMID: 28829958
قاعدة البيانات: MEDLINE
الوصف
تدمد:1573-2517
DOI:10.1016/j.jad.2017.08.014