دورية أكاديمية
أعرض في EDS

Bile Gastritis Following Laparoscopic Single Anastomosis Gastric Bypass: Pilot Study to Assess Significance of Bilirubin Level in Gastric Aspirate.

التفاصيل البيبلوغرافية
العنوان: Bile Gastritis Following Laparoscopic Single Anastomosis Gastric Bypass: Pilot Study to Assess Significance of Bilirubin Level in Gastric Aspirate.
المؤلفون: Shenouda MM; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Harb SE; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Mikhail SAA; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt. samehmikhail@kasralainy.edu.eg.; 8 Marguil Street, Zamalek, Cairo, 11211, Egypt. samehmikhail@kasralainy.edu.eg., Mokhtar SM; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Osman AMA; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Wassef ATS; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Rizkallah NNH; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Milad NM; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt., Anis SE; Department of Histopathology, Faculty of Medicine, Cairo University, Giza, Egypt., Nabil TM; Department of Surgery, Faculty of Medicine, BeniSuef University, Benisuef, Egypt., Zaki NS; Department of Surgery, Faculty of Medicine, Fayoum University, Fayoum, Egypt., Halepian A; Department of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
المصدر: Obesity surgery [Obes Surg] 2018 Feb; Vol. 28 (2), pp. 389-395.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 9106714 Publication Model: Print Cited Medium: Internet ISSN: 1708-0428 (Electronic) Linking ISSN: 09608923 NLM ISO Abbreviation: Obes Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: 2006- : New York : Springer Science + Business Media
Original Publication: Oxford, OX, UK : Rapid Communications of Oxford, [1991-
مواضيع طبية MeSH: Bile Reflux/*complications , Bilirubin/*metabolism , Gastric Bypass/*adverse effects , Gastric Mucosa/*metabolism , Gastritis/*etiology , Laparoscopy/*adverse effects , Obesity, Morbid/*surgery, Adolescent ; Adult ; Bile/physiology ; Bile Reflux/epidemiology ; Bile Reflux/metabolism ; Bile Reflux/pathology ; Bilirubin/analysis ; Biopsy, Needle ; Female ; Gastric Bypass/methods ; Gastritis/epidemiology ; Gastritis/metabolism ; Gastritis/pathology ; Humans ; Incidence ; Laparoscopy/methods ; Male ; Middle Aged ; Obesity, Morbid/epidemiology ; Obesity, Morbid/metabolism ; Obesity, Morbid/pathology ; Pilot Projects ; Postoperative Complications/epidemiology ; Postoperative Complications/metabolism ; Postoperative Complications/pathology ; Stomach/chemistry ; Stomach/pathology ; Young Adult
مستخلص: Introduction: Laparoscopic single anastomosis gastric bypass (SAGB) is increasingly performed for morbidly obese patients.
Aim of Work: This pilot study aims primarily at evaluating the incidence of bile gastritis after SAGB. The occurrence of reflux oesophagitis and reflux symptoms were also assessed.
Patients and Methods: This study included 20 patients having no reflux symptoms. All patients underwent a SAGB as a primary bariatric procedure by a single surgeon. Patients included consented to have an upper GI endoscopy done at 6 months postoperatively. Gastric aspirate was sent for bilirubin level assessment. Gastric and esophageal biopsies were submitted for histopathology and campylobacter-like organism (CLO) test.
Results: In our study, the rate of bile gastritis was 30%. In 18 patients, the level of bilirubin in gastric aspirate seems to be related to the degree of mucosal inflammation. The remaining two patients had microscopic moderate to severe gastritis with normal aspirate bilirubin level. Two patients with bilirubin level in aspirate more than 20 mg/dl had severe oesophagitis, gastritis with erosions, and metaplasia. Relationship between bilirubin level and histopathological findings of gastric biopsy examination was statistically significant with a P value of 0.001.
Conclusion: The incidence of bile gastritis in this cohort is higher than reported in the literature, and this may be worrying. The correlation between endoscopic findings and patients' symptoms is poor. Bilirubin level and pH in aspirate might be useful tools to confirm alkaline reflux. Its level might help to choose candidates for revision surgery after SAGB. This needs further validation with larger sample size.
التعليقات: Comment in: Obes Surg. 2018 Sep;28(9):2920-2921. (PMID: 29946753)
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فهرسة مساهمة: Keywords: Bile gastritis*; Bilirubin level*; Single anastomosis gastric bypass*
المشرفين على المادة: RFM9X3LJ49 (Bilirubin)
تواريخ الأحداث: Date Created: 20170830 Date Completed: 20181109 Latest Revision: 20190318
رمز التحديث: 20221213
DOI: 10.1007/s11695-017-2885-1
PMID: 28849330
قاعدة البيانات: MEDLINE
الوصف
تدمد:1708-0428
DOI:10.1007/s11695-017-2885-1