دورية أكاديمية
Eczema in Psoriatico: An Important Differential Diagnosis Between Chronic Allergic Contact Dermatitis and Psoriasis in Palmoplantar Localization.
| العنوان: | Eczema in Psoriatico: An Important Differential Diagnosis Between Chronic Allergic Contact Dermatitis and Psoriasis in Palmoplantar Localization. |
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| المؤلفون: | Kolesnik M; Department of Dermatology and Venereology, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, DE-39120 Magdeburg, Germany. malgorzata.kolesnik@med.ovgu.de., Franke I, Lux A, Quist SR, Gollnick HP |
| المصدر: | Acta dermato-venereologica [Acta Derm Venereol] 2018 Jan 12; Vol. 98 (1), pp. 50-58. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: MJS Publishing Country of Publication: Sweden NLM ID: 0370310 Publication Model: Print Cited Medium: Internet ISSN: 1651-2057 (Electronic) Linking ISSN: 00015555 NLM ISO Abbreviation: Acta Derm Venereol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2024- : Uppsala, Sweden : MJS Publishing Original Publication: Stockholm : Acta dermato-venereologica |
| مواضيع طبية MeSH: | Dermatitis, Allergic Contact/*diagnosis , Dermatitis, Allergic Contact/*metabolism , Interleukins/*metabolism , Psoriasis/*diagnosis , Psoriasis/*metabolism, Antigens, CD1/metabolism ; CD8-Positive T-Lymphocytes/pathology ; Chronic Disease ; Dermatitis, Allergic Contact/complications ; Dermatitis, Allergic Contact/pathology ; Diagnosis, Differential ; Filaggrin Proteins ; Histocompatibility Antigens Class I/metabolism ; Histocompatibility Antigens Class II/metabolism ; Humans ; Immunoglobulin E/blood ; Immunohistochemistry ; Intermediate Filament Proteins/metabolism ; Keratin-17/metabolism ; Ki-67 Antigen/metabolism ; Lymphocyte Count ; Psoriasis/complications ; Psoriasis/pathology ; T-Lymphocyte Subsets/pathology |
| مستخلص: | Differential diagnosis of palmoplantar non-pustular psoriasis and chronic allergic contact dermatitis (ACD) and the combination of these conditions, termed "eczema in psoriatico" (EIP), is difficult, especially in cases of isolated involvement. A blind re-evaluation of 63 archived formalin-fixed palmoplantar samples, previously diagnosed clinically as either psoriasis or chronic ACD, was performed. Samples were allocated to histopathological diagnoses of psoriasis, contact dermatitis or EIP. Immunohistological stainings were performed for better characterization. Immunochemistry of EIP revealed features that overlapped contemporarily with psoriasis (cytokeratin 17 (CK17), Ki67, interleukin (IL)-8, IL-17, IL-23) and with ACD (CD1a, major histocompatibility complex (MHC) class I, MHC class II, epidermal T-cell subsets). Surprisingly, a significantly much higher number of dermal CD8+ T cells was found in EIP than in ACD and psoriasis. In conclusion, this study provides insight into the immunohistological differentiation of palmoplantar psoriasis, chronic ACD and EIP. |
| المشرفين على المادة: | 0 (Antigens, CD1) 0 (CD1a antigen) 0 (Filaggrin Proteins) 0 (Histocompatibility Antigens Class I) 0 (Histocompatibility Antigens Class II) 0 (Interleukins) 0 (Intermediate Filament Proteins) 0 (Keratin-17) 0 (Ki-67 Antigen) 37341-29-0 (Immunoglobulin E) |
| تواريخ الأحداث: | Date Created: 20170831 Date Completed: 20180206 Latest Revision: 20211204 |
| رمز التحديث: | 20231215 |
| DOI: | 10.2340/00015555-2779 |
| PMID: | 28853491 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1651-2057 |
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| DOI: | 10.2340/00015555-2779 |