دورية أكاديمية
Mortality and Disability-Adjusted Life-Years (Dalys) for Common Neglected Tropical Diseases in Ethiopia, 1990-2015: Evidence from the Global Burden of Disease Study 2015.
| العنوان: | Mortality and Disability-Adjusted Life-Years (Dalys) for Common Neglected Tropical Diseases in Ethiopia, 1990-2015: Evidence from the Global Burden of Disease Study 2015. |
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| المؤلفون: | Deribew A; St. Paul Millennium Medical College, Addis Ababa, Ethiopia.; Dilla University, Dilla, Ethiopia.; Micronutrient Initiative, Ethiopia., Kebede B; Federal Ministry of Health, Addis Ababa, Ethiopia., Tessema GA; Department Reproductive Health, Institute of Public Health, University of Gondar, Gondar, Ethiopia.; School of Public Health, The University of Adelaide, Adelaide, Australia., Adama YA; School of Medicine, The University of Adelaide, Adelaide South Australia.; School of Public Health, Mekelle University, Mekelle, Ethiopia., Misganaw A; Institute for Health Metrics and Evaluation, University of Washington., Gebre T; International Trachoma Initiative, the Task Force for Global Health, Addis Ababa, Ethiopia., Hailu A; School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia., Biadgilign S; World Health Organization, Uganda., Amberbir A; Dignitas International, Zomba Malawi., Desalegn B; University of South Australia, Adelaide, Australia., Abajobir AA; School of Public Health, the University of Queensland, Queensland, Australia.; Debremarkos University, Debremarkos, Ethiopia., Shafi O; Rollind schools of public Health, Emory University, USA., Abera SF; School of Public Health, Mekelle University, Mekelle, Ethiopia.; Institute of Biological Chemistry and Nutrition, Hohenheim University, Stuttgart, Germany., Negussu N; Federal Ministry of Health, Addis Ababa, Ethiopia., Mengistu B; Federal Ministry of Health, Addis Ababa, Ethiopia., Amare AT; School of Medicine, The University of Adelaide, Adelaide South Australia.; College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia., Mulugeta A; World Health Organization, Addis Ababa, Ethiopia., Kebede Z; World Health Organization, Addis Ababa, Ethiopia., Mengistu B; Federal Ministry of Health, Addis Ababa, Ethiopia., Tadesse Z; The Carter Centre, Addis Ababa, Ethiopia., Sileshi M; Federal Ministry of Health, Addis Ababa, Ethiopia., Tamiru M; Federal Ministry of Health, Addis Ababa, Ethiopia., Chromwel EA; Institute for Health Metrics and Evaluation, University of Washington., Glenn SD; Institute for Health Metrics and Evaluation, University of Washington., Stanaway JD; Institute for Health Metrics and Evaluation, University of Washington., Deribe K; Wellcome Trust Brighton & Sussex Centre for Global Health Research, Brighton & Sussex Medical School, Falmer, Brighton, UK.; School of Public Health, Addis Ababa University, Ethiopia. |
| المصدر: | Ethiopian medical journal [Ethiop Med J] 2017; Vol. 55 (Suppl 1), pp. 3-14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Ethiopian Medical Association Country of Publication: Ethiopia NLM ID: 0373223 Publication Model: Print Cited Medium: Print ISSN: 0014-1755 (Print) Linking ISSN: 00141755 NLM ISO Abbreviation: Ethiop Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Addis Ababa : Ethiopian Medical Association |
| مواضيع طبية MeSH: | Quality-Adjusted Life Years*, Disabled Persons/*statistics & numerical data , Global Burden of Disease/*statistics & numerical data , Neglected Diseases/*mortality, Ethiopia/epidemiology ; Humans ; Mortality |
| مستخلص: | Introduction: Neglected tropical diseases (NTDs) are important public health problems in Ethiopia. In 2013, the Federal Ministry of Health (FMOH) has launched a national NTD master plan to eliminate major NTDs of public health importance by 2020. Benchmarking the current status of NTDs in the country is important to monitor and evaluate the progress in the implementation of interventions and their impacts. Therefore, this study aims to assess the trends of mortality and Disability-adjusted Life-Years (DALY) for the priority NTDs over the last 25 years. Methods: We used the Global Burden of Disease (GBD) 2015 estimates for this study. The GBD 2015 data source for cause of death and DALY estimation included verbal autopsy (VA), Demographic and Health Surveys (DHS), and other disease specific surveys, Ministry of Health reports submitted to United Nations (UN) agencies and published scientific articles. Cause of Death Ensemble modeling (CODEm) and/or natural history models were used to estimate NTDs mortality rates. DALY were estimated as the sum of Years of Life Lost (YLL) due to premature mortality and Years Lived with Disability (YLD). Results: All NTDs caused an estimated of 6,293 deaths (95% uncertainty interval (UI): 3699-10,080) in 1990 and 3,593 deaths (95% UI: 2051 - 6178) in 2015, a 43% reduction over the 25 years. Age-standardized mortality rates due to schistosomiasis, STH and leshmaniasis have declined by 91.3%, 73.5% and 21.6% respectively between 1990 to 2015. The number of DALYs due to all NTDs has declined from 814.4 thousand (95% UI: 548 thousand-1.2million) in 1990 to 579.5 thousand (95%UI: 309.4 thousand-1.3 million) in 2015. Age-standardized DALY rates due to all NTDs declined by 30.7%, from 17.6 per 1000(95%UI: 12.5-26.5) in 1990 to 12.2 per 1000(95%UI: 6.5 - 27.4) in 2015. Age-standardized DALY rate for trachoma declined from 92.7 per 100,000(95% UI: 63.2 - 128.4) in 1990 to 41.2 per 100,000(95%UI: 27.4-59.2) in 2015, a 55.6% reduction between 1990 and 2015. Age-standardized DALY rates for onchocerciasis, schistosomiasis and lymphiaticfilariasis decreased by 66.2%, 29.4% and 12.5% respectively between 1990 and 2015. DALY rate for ascariasis fell by 56.8% over the past 25 years. Conclusions: Ethiopia has made a remarkable progress in reducing the DALY rates for most of the NTDs over the last 25 years. The rapid scale of interventions and broader system strengthening may have a lasting impact on achieving the 2020 goal of elimination of most of NTDs. Ethiopia should strengthen the coverage of integrated interventions of NTD through proper coordination with other health programs and sectors and community participation to eliminate NTDs by 2020. |
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| معلومات مُعتمدة: | United Kingdom WT_ Wellcome Trust; 001 International WHO_ World Health Organization; 201900 United Kingdom WT_ Wellcome Trust; 201900/Z/16/Z United Kingdom WT_ Wellcome Trust |
| فهرسة مساهمة: | Keywords: DALY; Ethiopia; NTDs |
| تواريخ الأحداث: | Date Created: 20170908 Date Completed: 20180411 Latest Revision: 20240610 |
| رمز التحديث: | 20240610 |
| مُعرف محوري في PubMed: | PMC5582634 |
| PMID: | 28878427 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0014-1755 |
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