دورية أكاديمية
Combining therapeutic approaches: rTMS and aerobic exercise in post-stroke depression: a case series.
| العنوان: | Combining therapeutic approaches: rTMS and aerobic exercise in post-stroke depression: a case series. |
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| المؤلفون: | VanDerwerker CJ; a Department of Health Sciences and Research , Medical University of South Carolina , Charleston , SC , USA., Ross RE; a Department of Health Sciences and Research , Medical University of South Carolina , Charleston , SC , USA., Stimpson KH; b Department of Psychiatry , Stanford University , Stanford , CA , USA., Embry AE; a Department of Health Sciences and Research , Medical University of South Carolina , Charleston , SC , USA., Aaron SE; a Department of Health Sciences and Research , Medical University of South Carolina , Charleston , SC , USA., Cence B; c Ralph H. Johnson Veterans Affairs Medical Center , Charleston , SC , USA., George MS; c Ralph H. Johnson Veterans Affairs Medical Center , Charleston , SC , USA.; d Brain Stimulation Division, Department of Psychiatry and Behavioral Sciences , Medical University of South Carolina , Charleston , SC , USA.; e Department of Neurosciences , Medical University of South Carolina , Charleston , SC , USA., Gregory CM; a Department of Health Sciences and Research , Medical University of South Carolina , Charleston , SC , USA.; c Ralph H. Johnson Veterans Affairs Medical Center , Charleston , SC , USA. |
| المصدر: | Topics in stroke rehabilitation [Top Stroke Rehabil] 2018 Jan; Vol. 25 (1), pp. 61-67. Date of Electronic Publication: 2017 Oct 06. |
| نوع المنشور: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 9439750 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-5119 (Electronic) Linking ISSN: 10749357 NLM ISO Abbreviation: Top Stroke Rehabil Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Abingdon : Taylor & Francis Original Publication: Frederick, MD : Aspen Publishers, c1994- |
| مواضيع طبية MeSH: | Exercise*, Depression/*etiology , Depression/*rehabilitation , Stroke/*complications , Transcranial Magnetic Stimulation/*methods, Aged ; Aged, 80 and over ; Female ; Gait Disorders, Neurologic/etiology ; Gait Disorders, Neurologic/rehabilitation ; Humans ; Male ; Middle Aged ; Postural Balance/physiology ; Psychiatric Status Rating Scales ; Stroke/psychology ; Stroke Rehabilitation ; Treatment Outcome ; Walking |
| مستخلص: | Objective and importance Residual effects of stroke include well-documented functional limitations and high prevalence of depression. Repetitive transcranial magnetic stimulation (rTMS) and aerobic exercise (AEx) are established techniques that improve depressive symptoms, but a combination of the two has yet to be reported. The purpose of this case series is to examine the safety, feasibility, and impact of combined rTMS and AEx on post-stroke depression and functional mobility. Clinical presentation Three participants with a history of stroke and at least mild depressive symptoms (Patient Health Questionare-9 ≥5). Intervention Both rTMS and AEx were completed 3 times/week for 8-weeks. rTMS was applied to the left dorsolateral prefrontal cortex, 5000 pulses/session at 10 Hz, at an intensity of 120% of resting motor threshold. AEx consisted of 40 min of treadmill walking at 50-70% of heart rate reserve. Results Depressive symptoms improved in all three participants, with all demonstrating response (≥50% improvement in symptoms) and likely remission. All participants improved their Six Minute Walk Test distance and Participants 1 and 2 also improved Berg Balance Scale scores. Participants 1 and 3 improved overground walking speeds. No serious adverse events occurred with the application of rTMS or AEx and the participants' subjective reports indicated positive responses. Adherence rate for both rTMS and AEx was 98%. Conclusion Combined treatment of rTMS and AEx appears safe, feasible, and tolerable in individuals with a history of stroke and at least mild depressive symptoms. All participants had good compliance and demonstrated improvements in both depressive symptoms and walking capacity. |
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| معلومات مُعتمدة: | P20 GM109040 United States GM NIGMS NIH HHS; P2C HD086844 United States HD NICHD NIH HHS |
| فهرسة مساهمة: | Keywords: Stroke; aerobic exercise; depression; post-stroke depression; rehabilitation; repetitive transcranial magnetic stimulation (rTMS) |
| تواريخ الأحداث: | Date Created: 20171007 Date Completed: 20181012 Latest Revision: 20240313 |
| رمز التحديث: | 20240313 |
| مُعرف محوري في PubMed: | PMC5801693 |
| DOI: | 10.1080/10749357.2017.1374685 |
| PMID: | 28982298 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 1945-5119 |
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| DOI: | 10.1080/10749357.2017.1374685 |