دورية أكاديمية

Protein Composition of the Bovine Herpesvirus 1.1 Virion.

التفاصيل البيبلوغرافية
العنوان: Protein Composition of the Bovine Herpesvirus 1.1 Virion.
المؤلفون: Barber KA; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Mississippi State, MS 39762, USA. kaleyabarber@gmail.com., Daugherty HC; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Mississippi State, MS 39762, USA. hecdaugherty@gmail.com., Ander SE; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Mississippi State, MS 39762, USA. stephanie.e.ander@gmail.com., Jefferson VA; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Mississippi State, MS 39762, USA. vajefferson77@yahoo.com., Shack LA; Department of Basic Sciences, College of Veterinary Science, Mississippi State University, Mississippi State, MS 39762, USA., Pechan T; Institute for Genomics, Biocomputing and Biotechnology, Mississippi State University, Mississippi State, MS 39762, USA. pechan@ra.msstate.edu., Nanduri B; Department of Basic Sciences, College of Veterinary Science, Mississippi State University, Mississippi State, MS 39762, USA. BNanduri@cvm.msstate.edu., Meyer F; Department of Biochemistry, Molecular Biology, Entomology & Plant Pathology, Mississippi State University, Mississippi State, MS 39762, USA. florencia.meyer@msstate.edu.
المصدر: Veterinary sciences [Vet Sci] 2017 Feb 20; Vol. 4 (1). Date of Electronic Publication: 2017 Feb 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101680127 Publication Model: Electronic Cited Medium: Internet ISSN: 2306-7381 (Electronic) Linking ISSN: 23067381 NLM ISO Abbreviation: Vet Sci Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel : MDPI, [2014]-
مستخلص: Bovine herpesvirus (BoHV) type 1 is an important agricultural pathogen that infects cattle and other ruminants worldwide. Acute infection of the oro-respiratory tract leads to immune suppression and allows commensal bacteria to infect an otherwise healthy lower respiratory tract. This condition is known as the Bovine Respiratory Disease (BRD). BoHV-1 latently infects the host for life and periodical stress events re-initiate BRD, translating into high morbidity and large economic losses. To gain a better understanding of the biology of BoHV-1 and the disease it causes, we elucidated the protein composition of extracellular virions using liquid chromatography-mass spectrometry analysis. We detected 33 viral proteins, including the expected proteins of the nucleocapsid and envelope as well as other regulatory proteins present in the viral tegument. In addition to viral proteins, we have also identified packaged proteins of host origin. This constitutes the first proteomic characterization of the BoHV virion.
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معلومات مُعتمدة: P20 GM103476 United States GM NIGMS NIH HHS
فهرسة مساهمة: Keywords: bovine herpesvirus; proteomics; virion
تواريخ الأحداث: Date Created: 20171024 Latest Revision: 20201001
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC5606624
DOI: 10.3390/vetsci4010011
PMID: 29056670
قاعدة البيانات: MEDLINE
الوصف
تدمد:2306-7381
DOI:10.3390/vetsci4010011