دورية أكاديمية
Quantitative target proteomics of chromosome 13 human blood plasma proteins.
العنوان: | Quantitative target proteomics of chromosome 13 human blood plasma proteins. |
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المؤلفون: | Kopylov AT; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Ilgisonis EV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Tikhonova OV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Farafonova TE; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Novikova SE; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Zgoda VG; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia. vic@ibmh.msk.su., Ponomarenko EA; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Lisitsa AV; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia., Markin AA; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia., Morukov BV; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia., Grigoriev AI; Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, 123007, Russia., Archakov AI; Orekhovich Institute of Biomedical Chemistry, Moscow, 119121, Russia. |
المصدر: | Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2017 Sep; Vol. 476 (1), pp. 326-328. Date of Electronic Publication: 2017 Nov 04. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Pleiades Publishing Country of Publication: United States NLM ID: 101126895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1608-3091 (Electronic) Linking ISSN: 16076729 NLM ISO Abbreviation: Dokl Biochem Biophys Subsets: MEDLINE |
أسماء مطبوعة: | Publication: New York, NY : Pleiades Publishing Original Publication: Moscow, Russia : [Dordrecht] : International Academic Pub. Co. "Nauka/Interperiodica" ; Distributed worldwide by Kluwer Academic/Plenum Publishers, c2001- |
مواضيع طبية MeSH: | Proteomics*, Blood Proteins/*genetics , Blood Proteins/*metabolism , Chromosomes, Human, Pair 13/*genetics, Healthy Volunteers ; Humans |
مستخلص: | Quantitative proteomic analysis of 50 blood plasma samples of healthy volunteers who underwent a comprehensive medical examination and were found eligible for space flights was performed. As a result of directed mass spectrometric analysis, signals for 128 proteins, which accounted for nearly 40% of the total number of chromosome 13 gene products, were detected. The analysis of interindividual variation of concentrations of chromosome 13 proteins showed the presence of a pool comprising 41 proteins with a low variation (CV < 30%), which can potentially be used as biomarkers. |
References: | Mol Cell Proteomics. 2014 Mar;13(3):907-17. (PMID: 24443746) Nat Biotechnol. 2006 Mar;24(3):333-8. (PMID: 16525410) J Proteome Res. 2016 Nov 4;15(11):4039-4046. (PMID: 27457493) Expert Rev Proteomics. 2015 Apr;12(2):111-3. (PMID: 25711363) Clin Chem. 2008 Oct;54(10):1608-16. (PMID: 18687737) |
المشرفين على المادة: | 0 (Blood Proteins) |
تواريخ الأحداث: | Date Created: 20171105 Date Completed: 20171116 Latest Revision: 20181113 |
رمز التحديث: | 20240628 |
DOI: | 10.1134/S160767291705009X |
PMID: | 29101746 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1608-3091 |
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DOI: | 10.1134/S160767291705009X |