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Malignant glioma-primitive neuroectodermal tumor recurring as PNET-like only subdural collection: Case report.

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العنوان: Malignant glioma-primitive neuroectodermal tumor recurring as PNET-like only subdural collection: Case report.
المؤلفون: Alvarado AM; Department of Neurological Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA., Salacz ME; Department of Neuro-Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA., Chamoun RB; Department of Neurological Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
المصدر: Surgical neurology international [Surg Neurol Int] 2017 Oct 10; Vol. 8, pp. 243. Date of Electronic Publication: 2017 Oct 10 (Print Publication: 2017).
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Scientific Scholar LLC Country of Publication: United States NLM ID: 101535836 Publication Model: eCollection Cited Medium: Print ISSN: 2229-5097 (Print) Linking ISSN: 21527806 NLM ISO Abbreviation: Surg Neurol Int Subsets: PubMed not MEDLINE
أسماء مطبوعة: Publication: Pittsford, NY, USA : Scientific Scholar LLC
Original Publication: Mumbai : Medknow
مستخلص: Background: Histologic variants of conventional glioblastoma are rare clinical entities. In recent years, an aggressive variant termed malignant glioma with primitive neuroectodermal tumor components (MG-PNET) has been described in adults. In addition to the rarity of supratentorial primitive neuroectdoermal tumors (sPNET) in adults, MG-PNET can present with unique radiographic features.
Case Description: We report the case of a 42-year-old male who presented with headaches and vision changes. Magnetic resonance imaging (MRI) of the brain revealed a large right frontal lesion. He underwent craniotomy with pathology demonstrating glioblastoma WHO grade IV, with primitive neuroectodermal tumor-like components (MG-PNET). Seven weeks later the patient represented with worsening headaches and left-hand weakness. MRI brain revealed a diffusion restricting subdural collection overlying the prior craniotomy site. Biopsy revealed PNET-like recurrence of the previously treated MG-PNET.
Conclusion: In addition to histologic deviation, MG-PNET can present with variable radiographic findings on MRI and a clinical course distinctive from traditional glioblastoma. The hypercellular nature of this lesion can present as a diffusion-restricting lesion.
Competing Interests: There are no conflicts of interest.
References: Acta Neuropathol. 2002 Feb;103(2):193-8. (PMID: 11810187)
Am J Surg Pathol. 2011 Apr;35(4):573-82. (PMID: 21378543)
Onco Targets Ther. 2010 Sep 07;3:139-46. (PMID: 20856849)
Brain Pathol. 2009 Jan;19(1):81-90. (PMID: 18452568)
Int J Clin Exp Pathol. 2011;4(7):651-60. (PMID: 22076165)
Cureus. 2016 Jan 11;8(1):e456. (PMID: 26918224)
J Neurooncol. 2014 Sep;119(2):353-60. (PMID: 24893732)
J Med Case Rep. 2013 Mar 27;7:86. (PMID: 23537064)
J Neurooncol. 2002 Oct;60(1):43-52. (PMID: 12416545)
Eur J Radiol. 2006 Jun;58(3):394-403. (PMID: 16527438)
N Engl J Med. 2005 Mar 10;352(10 ):987-96. (PMID: 15758009)
فهرسة مساهمة: Keywords: Diffusion-weighted MRI; glioblastoma; platinum-based chemotherapy; primitive neuroectodermal tumor; temozolomide
تواريخ الأحداث: Date Created: 20171110 Latest Revision: 20220331
رمز التحديث: 20221213
مُعرف محوري في PubMed: PMC5655759
DOI: 10.4103/sni.sni_24_17
PMID: 29119041
قاعدة البيانات: MEDLINE
الوصف
تدمد:2229-5097
DOI:10.4103/sni.sni_24_17