تقرير
Malignant glioma-primitive neuroectodermal tumor recurring as PNET-like only subdural collection: Case report.
العنوان: | Malignant glioma-primitive neuroectodermal tumor recurring as PNET-like only subdural collection: Case report. |
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المؤلفون: | Alvarado AM; Department of Neurological Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA., Salacz ME; Department of Neuro-Oncology, University of Kansas Medical Center, Kansas City, Kansas, USA., Chamoun RB; Department of Neurological Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA. |
المصدر: | Surgical neurology international [Surg Neurol Int] 2017 Oct 10; Vol. 8, pp. 243. Date of Electronic Publication: 2017 Oct 10 (Print Publication: 2017). |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: Scientific Scholar LLC Country of Publication: United States NLM ID: 101535836 Publication Model: eCollection Cited Medium: Print ISSN: 2229-5097 (Print) Linking ISSN: 21527806 NLM ISO Abbreviation: Surg Neurol Int Subsets: PubMed not MEDLINE |
أسماء مطبوعة: | Publication: Pittsford, NY, USA : Scientific Scholar LLC Original Publication: Mumbai : Medknow |
مستخلص: | Background: Histologic variants of conventional glioblastoma are rare clinical entities. In recent years, an aggressive variant termed malignant glioma with primitive neuroectodermal tumor components (MG-PNET) has been described in adults. In addition to the rarity of supratentorial primitive neuroectdoermal tumors (sPNET) in adults, MG-PNET can present with unique radiographic features. Case Description: We report the case of a 42-year-old male who presented with headaches and vision changes. Magnetic resonance imaging (MRI) of the brain revealed a large right frontal lesion. He underwent craniotomy with pathology demonstrating glioblastoma WHO grade IV, with primitive neuroectodermal tumor-like components (MG-PNET). Seven weeks later the patient represented with worsening headaches and left-hand weakness. MRI brain revealed a diffusion restricting subdural collection overlying the prior craniotomy site. Biopsy revealed PNET-like recurrence of the previously treated MG-PNET. Conclusion: In addition to histologic deviation, MG-PNET can present with variable radiographic findings on MRI and a clinical course distinctive from traditional glioblastoma. The hypercellular nature of this lesion can present as a diffusion-restricting lesion. Competing Interests: There are no conflicts of interest. |
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فهرسة مساهمة: | Keywords: Diffusion-weighted MRI; glioblastoma; platinum-based chemotherapy; primitive neuroectodermal tumor; temozolomide |
تواريخ الأحداث: | Date Created: 20171110 Latest Revision: 20220331 |
رمز التحديث: | 20221213 |
مُعرف محوري في PubMed: | PMC5655759 |
DOI: | 10.4103/sni.sni_24_17 |
PMID: | 29119041 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2229-5097 |
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DOI: | 10.4103/sni.sni_24_17 |