دورية أكاديمية

Baccharis reticularia DC. and Limonene Nanoemulsions: Promising Larvicidal Agents for Aedes aegypti (Diptera: Culicidae) Control.

التفاصيل البيبلوغرافية
العنوان: Baccharis reticularia DC. and Limonene Nanoemulsions: Promising Larvicidal Agents for Aedes aegypti (Diptera: Culicidae) Control.
المؤلفون: Botas GDS; Walter Mors Institute of Research on Natural Products, Federal University of Rio de Janeiro, Rio de Janeiro RJ 21941-902, Brazil. giselebotas@gmail.com., Cruz RAS; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. rodrigo@unifap.br., de Almeida FB; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. fb_almeida@id.uff.br., Duarte JL; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. jonatasdlobato@gmail.com., Araújo RS; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. raquelaraujo_op@yahoo.com.br., Souto RNP; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. rnpsouto@unifap.br., Ferreira R; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. triato.ricardo@hotmail.com., Carvalho JCT; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. jctcarvalho@gmail.com., Santos MG; Faculty of Teacher Training, University of the State of Rio de Janeiro, São Gonçalo RJ 24435-005, Brazil. marceloguerrasantos@gmail.com., Rocha L; Department of Pharmaceutical Technology, Faculty of Pharmacy, Fluminense Federal University, Niterói RJ 24210-346, Brazil. lean@vm.uff.br., Pereira VLP; Walter Mors Institute of Research on Natural Products, Federal University of Rio de Janeiro, Rio de Janeiro RJ 21941-902, Brazil. patrocinio.ufrj@gmail.com., Fernandes CP; Department of Biological and Health Sciences, Federal University of Amapá, Macapá AP 68.903-419, Brazil. caio_pfernandes@yahoo.com.br.
المصدر: Molecules (Basel, Switzerland) [Molecules] 2017 Nov 17; Vol. 22 (11). Date of Electronic Publication: 2017 Nov 17.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c1995-
مواضيع طبية MeSH: Baccharis/*chemistry , Cyclohexenes/*chemistry , Cyclohexenes/*pharmacology , Insecticides/*chemistry , Insecticides/*pharmacology , Terpenes/*chemistry , Terpenes/*pharmacology, Aedes/drug effects ; Animals ; Brazil ; Gas Chromatography-Mass Spectrometry ; Larva/drug effects ; Limonene ; Mosquito Control ; Oils, Volatile/chemistry ; Oils, Volatile/pharmacology ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology
مستخلص: Baccharis reticularia DC. is a plant species from the Asteraceae family that is endemic to Brazil. Despite the great importance of Baccharis genus, no study has been carried out regarding either the phytochemical composition of B. reticularia or the evaluation of its larvicidal potential. Considering the intrinsic immiscibility of essential oils, this study shows larvicidal nanoemulsions containing the B. reticularia phytochemically characterized essential oil and its main constituent against Aedes aegypti . The major compound found was d-limonene (25.7%). The essential oil inhibited the acetylcholinesterase, one of the main targets of insecticides. The required hydrophile-lipophile balance of both nanoemulsions was 15.0. The mean droplet sizes were around 90.0 nm, and no major alterations were observed after 24 h of preparation for both formulations. After 48 h of treatment, the estimated LC 50 values were 118.94 μg mL -1 and 81.19 μg mL -1 for B. reticularia essential oil and d-limonene nanoemulsions, respectively. Morphological alterations evidenced by scanning electron micrography were observed on the larvae treated with the d-limonene nanoemulsion. This paper demonstrated a simple and ecofriendly method for obtaining B. reticularia essential oil and d-limonene aqueous nanoemulsions by a non-heating and solvent-free method, as promising alternatives for Aedes aegypti control.
Competing Interests: The authors declare no conflict of interest.
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فهرسة مساهمة: Keywords: Asteraceae; early stage fourth-instar larvae; low energy method; scanning electron microscopy
المشرفين على المادة: 0 (Cyclohexenes)
0 (Insecticides)
0 (Oils, Volatile)
0 (Phytochemicals)
0 (Plant Extracts)
0 (Terpenes)
9MC3I34447 (Limonene)
تواريخ الأحداث: Date Created: 20171118 Date Completed: 20180626 Latest Revision: 20181207
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC6150371
DOI: 10.3390/molecules22111990
PMID: 29149027
قاعدة البيانات: MEDLINE
الوصف
تدمد:1420-3049
DOI:10.3390/molecules22111990