التفاصيل البيبلوغرافية
| العنوان: |
Functions of microRNAs in osteoporosis. |
| المؤلفون: |
Ge DW; Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. leiyangspine@163.com., Wang WW, Chen HT, Yang L, Cao XJ |
| المصدر: |
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] 2017 Nov; Vol. 21 (21), pp. 4784-4789. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Verduci Country of Publication: Italy NLM ID: 9717360 Publication Model: Print Cited Medium: Internet ISSN: 2284-0729 (Electronic) Linking ISSN: 11283602 NLM ISO Abbreviation: Eur Rev Med Pharmacol Sci Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Rome : Verduci, [1997- |
| مواضيع طبية MeSH: |
MicroRNAs/*metabolism , Osteoporosis/*pathology, Bone Remodeling ; Cell Differentiation/genetics ; Humans ; Osteoblasts/cytology ; Osteoblasts/metabolism ; Osteoclasts/metabolism ; Osteoporosis/genetics |
| مستخلص: |
Osteoporosis (OP) is a kind of disease with a 25% incidence, characterized by the bone mass loss, bone microstructure damage, increased bone fragility, and easy fracture. miRNA plays an important regulatory role in the process of bone remodeling, especially in the regulation of differentiation and function of osteoblasts and osteoclasts, and the development and progression of OP and other bone diseases. In the future, it is expected to delay the bone loss and promote the bone remodeling via the overexpression or inhibition of specific miRNAs in specific tissues, thereby treating OP. |
| المشرفين على المادة: |
0 (MicroRNAs) |
| تواريخ الأحداث: |
Date Created: 20171123 Date Completed: 20180807 Latest Revision: 20181202 |
| رمز التحديث: |
20221213 |
| PMID: |
29164586 |
| قاعدة البيانات: |
MEDLINE |
