دورية أكاديمية
أعرض في EDS

Expression of genes related to antioxidant activity in Nile tilapia kept under salinity stress and fed diets containing different levels of vitamin C.

التفاصيل البيبلوغرافية
العنوان: Expression of genes related to antioxidant activity in Nile tilapia kept under salinity stress and fed diets containing different levels of vitamin C.
المؤلفون: Caxico Vieira CAS; a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil., Vieira JS; a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil., Bastos MS; a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil., Zancanela V; b Animal Science Department , Estadual University of Maringá , Maringá , Brazil., Barbosa LT; a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil., Gasparino E; b Animal Science Department , Estadual University of Maringá , Maringá , Brazil., Del Vesco AP; a Animal Science Department , Federal University of Sergipe , São Cristñvão , Brazil.
المصدر: Journal of toxicology and environmental health. Part A [J Toxicol Environ Health A] 2018; Vol. 81 (1-3), pp. 20-30. Date of Electronic Publication: 2017 Nov 27.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 100960995 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-7394 (Print) Linking ISSN: 00984108 NLM ISO Abbreviation: J Toxicol Environ Health A Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Washington, D.C. ; London : Taylor & Francis, c1998-
مواضيع طبية MeSH: Gene Expression*, Ascorbic Acid/*pharmacology , Cichlids/*genetics, Animal Feed ; Animals ; Catalase/genetics ; Fishes ; Glutathione Peroxidase/genetics ; Glutathione Reductase/genetics ; Glutathione Synthase/genetics ; HSP70 Heat-Shock Proteins/genetics ; Salinity ; Survival Rate
مستخلص: The aim of this study was to examine whether (1) severe changes in salinity produced increased stress, and (2) vitamin C supplementation might reduce the observed damage in Nile tilapia. The parameters measured included condition factor, survival rate, and gene expression of catalase (CAT), heat shock protein 70 (HSP70), glutathione reductase (GSR), glutathione synthase (GSS), and glutathione peroxidase (GPx). The investigation was conducted with 160 Nile tilapia divided into four treatment groups: freshwater; 7 or 21 parts per thousand (‰) salinity, all fed a basal diet; as well as a fourth treatment group consisting of fish kept at 21‰ salinity fed a diet supplemented with vitamin C (1500 mg/kg). For gene expression analysis, liver samples were collected after 24 h or after 14 d. After 24 h, fish raised in 21‰ salinity and fed with the diet supplemented with vitamin C showed similar GPx expression as the control freshwater group. GSS expression in 21‰ salinity was similar to fish exposed to 7‰ salinity. Nile tilapia exposed to 21‰ salinity without vitamin C supplementation exhibited the highest HSP70 gene expression levels after 24 h. After 14-dtreatment, the lowest survival rate was observed in the 21‰ salinity group. After 14 d, the highest expression of GPx and GSR levels was detected in fish in the 21‰ salinity group that received vitamin C. Data indicate that vitamin C supplementation enhanced the expression of genes related to antioxidant capacity in Nile tilapia exposed to higher salinity, thereby increasing protection against the oxidative effects induced by high water salinity..
المشرفين على المادة: 0 (HSP70 Heat-Shock Proteins)
EC 1.11.1.6 (Catalase)
EC 1.11.1.9 (Glutathione Peroxidase)
EC 1.8.1.7 (Glutathione Reductase)
EC 6.3.2.3 (Glutathione Synthase)
PQ6CK8PD0R (Ascorbic Acid)
تواريخ الأحداث: Date Created: 20171128 Date Completed: 20171215 Latest Revision: 20181125
رمز التحديث: 20240628
DOI: 10.1080/15287394.2017.1401968
PMID: 29173066
قاعدة البيانات: MEDLINE
الوصف
تدمد:1528-7394
DOI:10.1080/15287394.2017.1401968