دورية أكاديمية
Grades of nodular sclerosis (NSI-NSII) in Hodgkin's disease. Are they of independent prognostic value?
| العنوان: | Grades of nodular sclerosis (NSI-NSII) in Hodgkin's disease. Are they of independent prognostic value? |
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| المؤلفون: | Wijlhuizen TJ; Integraal Kankercentrum Zuid, Sooz, Tilburg, Eindhoven, The Netherlands., Vrints LW, Jairam R, Breed WP, Wijnen JT, Bosch LJ, Crommelin MA, van Dam FE, de Koning J, Verhagen-Teulings M |
| المصدر: | Cancer [Cancer] 1989 Mar 15; Vol. 63 (6), pp. 1150-3. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print Cited Medium: Print ISSN: 0008-543X (Print) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005- >: Hoboken, NJ : Wiley Original Publication: New York [etc.] Published for the American Cancer Society by J. Wiley [etc.] |
| مواضيع طبية MeSH: | Hodgkin Disease/*pathology, Adult ; Blood Sedimentation ; Female ; Hodgkin Disease/blood ; Hodgkin Disease/mortality ; Humans ; Male ; Prognosis ; Retrospective Studies ; Sclerosis/pathology |
| مستخلص: | Subclassification of the nodular sclerosis (NS) type of Hodgkin's disease in Grade 1 and 2 was reported for the first time by the British National Lymphoma Investigation (BNLI). Three groups, the BNLI, Gärtner et al. and the current authors, found clearly different survival rates between Grade 1 and 2 NS patients. The authors studied retrospectively if this NS grading has an independent prognostic value in 90 NS patients, diagnosed in ten hospitals in the southeastern part of the Netherlands (1972-1983). In this study there is no significant difference in sex, age, B-symptoms, erythrocyte sedimentation rate (ESR), stage, positive laparotomy, involvement of mediastinum or spleen, lymphocyte count, and percentage of complete remissions between the NS subgroups. Multivariate analysis suggests that the subclassification of NS in Grades 1 and 2 is a prognostic factor in survival independent of age, stage and ESR. This finding and the high relative frequency of NS makes application of this NS subdivision probably clinically useful to identify patients for a risk-adapted therapy. |
| تواريخ الأحداث: | Date Created: 19890315 Date Completed: 19890405 Latest Revision: 20190619 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1002/1097-0142(19890315)63:6<1150::aid-cncr2820630618>3.0.co;2-4 |
| PMID: | 2917317 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0008-543X |
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| DOI: | 10.1002/1097-0142(19890315)63:6<1150::aid-cncr2820630618>3.0.co;2-4 |