دورية أكاديمية
أعرض في EDS

Validation of an UHPLC-MS/MS Method for Screening of Antimicrobial Residues in Eggs and Their Application to Analyses of Eggs from Laying Hens Subjected to Pharmacological Treatment.

التفاصيل البيبلوغرافية
العنوان: Validation of an UHPLC-MS/MS Method for Screening of Antimicrobial Residues in Eggs and Their Application to Analyses of Eggs from Laying Hens Subjected to Pharmacological Treatment.
المؤلفون: Caldeira LGM; Escola de Veterinária, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos 6627, 30.123-970 Belo Horizonte, MG, Brazil., Santos FA; Laboratório Nacional Agropecuário (Lanagro-MG), Av. Rômulo Joviano s/n, 33.600-000 Pedro Leopoldo, MG, Brazil., de Oliveira AMG; Laboratório Nacional Agropecuário (Lanagro-MG), Av. Rômulo Joviano s/n, 33.600-000 Pedro Leopoldo, MG, Brazil., Lima JA; Laboratório Nacional Agropecuário (Lanagro-MG), Av. Rômulo Joviano s/n, 33.600-000 Pedro Leopoldo, MG, Brazil., de Souza LF; Laboratório Nacional Agropecuário (Lanagro-MG), Av. Rômulo Joviano s/n, 33.600-000 Pedro Leopoldo, MG, Brazil., da Silva GR; Escola de Veterinária, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos 6627, 30.123-970 Belo Horizonte, MG, Brazil., de Assis DCS; Escola de Veterinária, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos 6627, 30.123-970 Belo Horizonte, MG, Brazil., Cançado SV; Escola de Veterinária, Universidade Federal de Minas Gerais (UFMG), Av. Antônio Carlos 6627, 30.123-970 Belo Horizonte, MG, Brazil.
المصدر: Journal of analytical methods in chemistry [J Anal Methods Chem] 2017; Vol. 2017, pp. 3259073. Date of Electronic Publication: 2017 Oct 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Hindawi Pub. Corp Country of Publication: Egypt NLM ID: 101575377 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2090-8865 (Print) Linking ISSN: 20908873 NLM ISO Abbreviation: J Anal Methods Chem Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Cario : Hindawi Pub. Corp.
مستخلص: A multiresidue method by UHPLC/MS-MS was optimized and validated for the screening and semiquantitative detection of antimicrobials residues from tetracyclines, aminoglycosides, quinolones, lincosamides, β -lactams, sulfonamides, and macrolides families in eggs. A qualitative approach was used to ensure adequate sensitivity to detect residues at the level of interest, defined as maximum residue limit (MRL), or less. The applicability of the methods was assessed by analyzing egg samples from hens that had been subjected to pharmacological treatment with neomycin, enrofloxacin, lincomycin, oxytetracycline, and doxycycline during five days and after discontinuation of medication (10 days). The method was adequate for screening all studied analytes in eggs, since the performance parameters ensured a false-compliant rate below or equal to 5%, except for flumequine. In the analyses of eggs from laying hens subjected to pharmacological treatment, all antimicrobial residues were detected throughout the experimental period, even after discontinuation of medication, except for neomycin, demonstrating the applicability of the method for analyses of antimicrobial residues in eggs.
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تواريخ الأحداث: Date Created: 20171129 Latest Revision: 20240327
رمز التحديث: 20240327
مُعرف محوري في PubMed: PMC5664282
DOI: 10.1155/2017/3259073
PMID: 29181222
قاعدة البيانات: MEDLINE
الوصف
تدمد:2090-8865
DOI:10.1155/2017/3259073