دورية أكاديمية
Are on-scene blood transfusions by a helicopter emergency medical service useful and safe? A multicentre case-control study.
| العنوان: | Are on-scene blood transfusions by a helicopter emergency medical service useful and safe? A multicentre case-control study. |
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| المؤلفون: | Peters JH; Department of Trauma Surgery.; Helicopter Emergency Medical Service., Smulders PSH; Radboud University, Nijmegen., Moors XRJ; Department of Pediatric Anesthesiology, Erasmus University Medical Center-Sophia Children's Hospital.; Helicopter Emergency Medical Service, Erasmus University Medical Center., Bouman SJM; Erasmus University, Rotterdam., Meijs CMEM; Department of Surgery, Ziekenhuis Rivierenland, Tiel, The Netherlands., Hoogerwerf N; Helicopter Emergency Medical Service.; Department of Anaesthesiology, Radboud University Medical Center., Edwards MJR; Department of Trauma Surgery. |
| المصدر: | European journal of emergency medicine : official journal of the European Society for Emergency Medicine [Eur J Emerg Med] 2019 Apr; Vol. 26 (2), pp. 128-132. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 9442482 Publication Model: Print Cited Medium: Internet ISSN: 1473-5695 (Electronic) Linking ISSN: 09699546 NLM ISO Abbreviation: Eur J Emerg Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: London : Lippincott Williams & Wilkins Original Publication: London, UK : Chapman & Hall, 1994- |
| مواضيع طبية MeSH: | Air Ambulances* , Patient Safety*, Blood Transfusion/*methods , Emergency Medical Services/*methods , Resuscitation/*methods, Adult ; Case-Control Studies ; Emergency Service, Hospital ; Female ; Humans ; Male ; Middle Aged ; Platelet Transfusion/methods ; Transportation of Patients ; Young Adult |
| مستخلص: | Introduction: In the prehospital setting, crystalloid fluids are frequently used, but only erythrocytes are capable of transporting oxygen to tissues. The aim of this study was to establish the efficacy and safety of the prehospital use of uncross matched type O rhesus-negative packed red blood cells (URBC) by the Dutch physician-staffed helicopter emergency medical service. We hypothesized that prehospital URBC transfusions are safe and more effective with respect to survival than resuscitations with crystalloids. Methods: The effects of prehospital URBC transfusions were studied by comparing a cohort of patients (>18 years) who were treated with a combination of URBC and crystalloid fluids with a matched control group of patients who received crystalloid fluids alone. Results: Among 73 adults who received prehospital URBC transfusions, 50 (68%) patients were included. No transfusion reactions were observed. No effect of prehospital transfusion on 24-h or 30-day survival was found. Haemoglobin levels at presentation to the emergency department were higher in the URBC cohort. The two groups had similar cumulative erythrocyte requirements within the first 24 h. Conclusion: Neither survival benefits nor a decreased incidence of shock on admission were observed after prehospital helicopter emergency medical service URBC transfusions. There were no prehospital transfusion reactions in this study; therefore, URBC transfusions were deemed to be safe. A prospective randomized study is warranted to evaluate the effect of early URBC transfusions and transfusions with preheated URBC on the survival of patients with severe prehospital haemorrhagic shock. |
| تواريخ الأحداث: | Date Created: 20171201 Date Completed: 20190612 Latest Revision: 20190613 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1097/MEJ.0000000000000516 |
| PMID: | 29189297 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1473-5695 |
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| DOI: | 10.1097/MEJ.0000000000000516 |