Lymphocutaneous Sporotrichosis Treated with Potassium Iodide with Development of Subclinical Hypothyroidism: Wolff-Chaikoff Effect?

التفاصيل البيبلوغرافية
العنوان: Lymphocutaneous Sporotrichosis Treated with Potassium Iodide with Development of Subclinical Hypothyroidism: Wolff-Chaikoff Effect?
المؤلفون: Arora P; Department of Dermatology, Dr Ram Manohar Lohia Hospital, New Delhi, India., Raihan M; Department of Dermatology, Rama Medical College, Ghaziabad, Uttar Pradesh, India., Kubba A; Department of Pathology, Delhi Dermpath Laboratory, Delhi Dermatology Group, New Delhi, India., Gautam RK; Department of Dermatology, Dr Ram Manohar Lohia Hospital, New Delhi, India.
المصدر: Indian dermatology online journal [Indian Dermatol Online J] 2017 Nov-Dec; Vol. 8 (6), pp. 475-477.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Medknow Publications Pvt. Ltd Country of Publication: India NLM ID: 101586880 Publication Model: Print Cited Medium: Print ISSN: 2229-5178 (Print) Linking ISSN: 22295178 NLM ISO Abbreviation: Indian Dermatol Online J Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Mumbai : Medknow Publications Pvt. Ltd.
مستخلص: Sporotrichosis is a subcutaneous mycotic infection caused by Sporothrix schenckii that is acquired by traumatic implantation. The diagnosis is established by demonstration of fungal elements on histopathology and culture. Potassium iodide, azole antifungals, and terbinafine are the treatment options available. In this article, we report a 60-year-old female with lymphocutaneous sporotrichosis that responded well to potassium iodide. However, subclinical hypothyroidism (Wolff-Chaikoff effect) was encountered as a side effect of therapy which was managed with thyroxine replacement. Knowledge about the Wolff-Chaikoff effect (WCE) is important for the dermatologist and reinforces the need for screening and monitoring of thyroid stimulating hormone (TSH) in patients where long duration therapy is being planned.
Competing Interests: There are no conflicts of interest.
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فهرسة مساهمة: Keywords: Itraconazole; Wolff-Chaikoff effect; potassium iodide; sporotrichosis
تواريخ الأحداث: Date Created: 20171206 Latest Revision: 20201001
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC5707842
DOI: 10.4103/idoj.IDOJ_3_17
PMID: 29204393
قاعدة البيانات: MEDLINE
الوصف
تدمد:2229-5178
DOI:10.4103/idoj.IDOJ_3_17