دورية أكاديمية
أعرض في EDS

Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock.

التفاصيل البيبلوغرافية
العنوان: Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock.
المؤلفون: Biyikli E; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey., Kayipmaz AE; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey. Electronic address: aekayipmaz@baskent.edu.tr., Kavalci C; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey.
المصدر: The American journal of emergency medicine [Am J Emerg Med] 2018 Apr; Vol. 36 (4), pp. 647-650. Date of Electronic Publication: 2017 Dec 06.
نوع المنشور: Journal Article; Observational Study
اللغة: English
بيانات الدورية: Publisher: W B Saunders Country of Publication: United States NLM ID: 8309942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8171 (Electronic) Linking ISSN: 07356757 NLM ISO Abbreviation: Am J Emerg Med Subsets: MEDLINE
أسماء مطبوعة: Publication: 1983- : Philadelphia, PA : W B Saunders
Original Publication: [Philadelphia, PA. : Centrum Philadelphia, c1983]-
مواضيع طبية MeSH: Hospital Mortality* , Lymphocyte Count* , Platelet Count*, Lactic Acid/*blood , Sepsis/*mortality , Shock, Septic/*mortality, Blood Pressure ; Blood Urea Nitrogen ; Emergency Service, Hospital ; Glasgow Coma Scale ; Humans ; Respiration, Artificial ; Retrospective Studies ; Sepsis/blood ; Severity of Illness Index ; Shock, Septic/blood
مستخلص: Background: Sepsis is a potentially fatal condition with high treatment costs, and is especially common among the elderly population. The emergency management of septic patients has gained importance.
Objective: Herein, we investigated the effect of admission lactate levels and the platelet-lymphocyte ratio (PLR) on the 30-day mortality among patients older than 65years who were diagnosed with sepsis and septic shock according to the qSOFA criteria at our hospital's emergency department.
Methods: This observational study was conducted retrospectively. We obtained information regarding patients' demographic characteristics, comorbid conditions, hemodynamic parameters at admission, initial treatment needs at the emergency department.
Results: 131 patients received a diagnosis of sepsis and septic shock at our emergency department in two years. Among these, 45% (n=59) of the patients died within 30days of admission. Forty (30.5%) patients required mechanical ventilation. There was a significant difference between the survival and non-survival groups with regard to systolic and diastolic blood pressures (p=0.013 and 0.045, respectively). There were significant differences between the two groups with respect to the Glasgow Coma Scale score (p<0.001) and BUN levels (p<0.001). The mortality status according to qSOFA scores was revealed a significant difference between the two groups (p<0.001).
Conclusion: Our results showed that the patients who died within 30days of admission and those who did not had comparable PLR and lactate levels (p=0.821 and 0.120, respectively). We opine that serial lactate measurements would be more useful than a single admission lactate measurement for the prediction of mortality.
(Copyright © 2017. Published by Elsevier Inc.)
فهرسة مساهمة: Keywords: Emergency treatment; Infection; Severe sepsis
المشرفين على المادة: 33X04XA5AT (Lactic Acid)
تواريخ الأحداث: Date Created: 20171212 Date Completed: 20181122 Latest Revision: 20181122
رمز التحديث: 20240628
DOI: 10.1016/j.ajem.2017.12.010
PMID: 29225011
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-8171
DOI:10.1016/j.ajem.2017.12.010