دورية أكاديمية
Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock.
العنوان: | Effect of platelet-lymphocyte ratio and lactate levels obtained on mortality with sepsis and septic shock. |
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المؤلفون: | Biyikli E; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey., Kayipmaz AE; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey. Electronic address: aekayipmaz@baskent.edu.tr., Kavalci C; Baskent University Faculty of Medicine, Department of Emergency, Ankara, Turkey. |
المصدر: | The American journal of emergency medicine [Am J Emerg Med] 2018 Apr; Vol. 36 (4), pp. 647-650. Date of Electronic Publication: 2017 Dec 06. |
نوع المنشور: | Journal Article; Observational Study |
اللغة: | English |
بيانات الدورية: | Publisher: W B Saunders Country of Publication: United States NLM ID: 8309942 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8171 (Electronic) Linking ISSN: 07356757 NLM ISO Abbreviation: Am J Emerg Med Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 1983- : Philadelphia, PA : W B Saunders Original Publication: [Philadelphia, PA. : Centrum Philadelphia, c1983]- |
مواضيع طبية MeSH: | Hospital Mortality* , Lymphocyte Count* , Platelet Count*, Lactic Acid/*blood , Sepsis/*mortality , Shock, Septic/*mortality, Blood Pressure ; Blood Urea Nitrogen ; Emergency Service, Hospital ; Glasgow Coma Scale ; Humans ; Respiration, Artificial ; Retrospective Studies ; Sepsis/blood ; Severity of Illness Index ; Shock, Septic/blood |
مستخلص: | Background: Sepsis is a potentially fatal condition with high treatment costs, and is especially common among the elderly population. The emergency management of septic patients has gained importance. Objective: Herein, we investigated the effect of admission lactate levels and the platelet-lymphocyte ratio (PLR) on the 30-day mortality among patients older than 65years who were diagnosed with sepsis and septic shock according to the qSOFA criteria at our hospital's emergency department. Methods: This observational study was conducted retrospectively. We obtained information regarding patients' demographic characteristics, comorbid conditions, hemodynamic parameters at admission, initial treatment needs at the emergency department. Results: 131 patients received a diagnosis of sepsis and septic shock at our emergency department in two years. Among these, 45% (n=59) of the patients died within 30days of admission. Forty (30.5%) patients required mechanical ventilation. There was a significant difference between the survival and non-survival groups with regard to systolic and diastolic blood pressures (p=0.013 and 0.045, respectively). There were significant differences between the two groups with respect to the Glasgow Coma Scale score (p<0.001) and BUN levels (p<0.001). The mortality status according to qSOFA scores was revealed a significant difference between the two groups (p<0.001). Conclusion: Our results showed that the patients who died within 30days of admission and those who did not had comparable PLR and lactate levels (p=0.821 and 0.120, respectively). We opine that serial lactate measurements would be more useful than a single admission lactate measurement for the prediction of mortality. (Copyright © 2017. Published by Elsevier Inc.) |
فهرسة مساهمة: | Keywords: Emergency treatment; Infection; Severe sepsis |
المشرفين على المادة: | 33X04XA5AT (Lactic Acid) |
تواريخ الأحداث: | Date Created: 20171212 Date Completed: 20181122 Latest Revision: 20181122 |
رمز التحديث: | 20240628 |
DOI: | 10.1016/j.ajem.2017.12.010 |
PMID: | 29225011 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1532-8171 |
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DOI: | 10.1016/j.ajem.2017.12.010 |