دورية أكاديمية
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Automated Detection of Iris Furrows and their Influence on Dynamic Iris Volume Change.

التفاصيل البيبلوغرافية
العنوان: Automated Detection of Iris Furrows and their Influence on Dynamic Iris Volume Change.
المؤلفون: Chua J; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Thakku SG; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Pham TH; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore., Lee R; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Tun TA; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Nongpiur ME; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Tan MCL; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Quah JHM; SingHealth Polyclinics, Outram, Singapore., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Girard MJA; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg.
المصدر: Scientific reports [Sci Rep] 2017 Dec 20; Vol. 7 (1), pp. 17894. Date of Electronic Publication: 2017 Dec 20.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : Nature Publishing Group, copyright 2011-
مواضيع طبية MeSH: Iris/*anatomy & histology, Female ; Humans ; Intraocular Pressure/physiology ; Male ; Middle Aged ; Prospective Studies ; Pupil/physiology ; Tomography, Optical Coherence/methods
مستخلص: We introduced a new method for detecting iris surface furrows and identify its associations with dynamic changes in iris volume in healthy eyes. Swept-source optical coherence tomography was performed on 65 subjects with open angle under light and dark conditions. Iris boundaries were identified and a reconstruction of the anterior iris surface was obtained. Furrows were detected by identifying locally deep (minima) points on the iris surface and reported as furrow length in millimetres. Iris volume was quantified. Associations between furrow length and dynamic changes in iris volume were assessed using linear regression model. With pupil dilation, furrow length increased (15.84 mm) whereas iris volume decreased (-1.19 ± 0.66 mm 3 ). Longer furrow length was associated with larger static iris volume, as well as smaller loss of iris volume with pupil dilation (β = -0.10, representing 0.1 mm 3 less loss in iris volume per 10 mm increase in iris furrow length; P = 0.002, adjusted for age, gender and changes in pupil size). Our iris furrow length measurements are robust and intuitive. Eyes with longer furrows have larger iris volume and lose less volume during physiological pupil dilation. These findings highlight the potential for iris surface features as indicators of iris morphological behavior.
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تواريخ الأحداث: Date Created: 20171222 Date Completed: 20190715 Latest Revision: 20190715
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC5738384
DOI: 10.1038/s41598-017-18039-w
PMID: 29263345
قاعدة البيانات: MEDLINE
الوصف
تدمد:2045-2322
DOI:10.1038/s41598-017-18039-w