دورية أكاديمية
Automated Detection of Iris Furrows and their Influence on Dynamic Iris Volume Change.
العنوان: | Automated Detection of Iris Furrows and their Influence on Dynamic Iris Volume Change. |
---|---|
المؤلفون: | Chua J; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Thakku SG; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Pham TH; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore., Lee R; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Tun TA; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Nongpiur ME; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore., Tan MCL; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Quah JHM; SingHealth Polyclinics, Outram, Singapore., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore., Girard MJA; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.; Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg.; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore and National University Health System, Singapore, Singapore. chingyu.cheng@duke-nus.edu.sg. |
المصدر: | Scientific reports [Sci Rep] 2017 Dec 20; Vol. 7 (1), pp. 17894. Date of Electronic Publication: 2017 Dec 20. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
اللغة: | English |
بيانات الدورية: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London : Nature Publishing Group, copyright 2011- |
مواضيع طبية MeSH: | Iris/*anatomy & histology, Female ; Humans ; Intraocular Pressure/physiology ; Male ; Middle Aged ; Prospective Studies ; Pupil/physiology ; Tomography, Optical Coherence/methods |
مستخلص: | We introduced a new method for detecting iris surface furrows and identify its associations with dynamic changes in iris volume in healthy eyes. Swept-source optical coherence tomography was performed on 65 subjects with open angle under light and dark conditions. Iris boundaries were identified and a reconstruction of the anterior iris surface was obtained. Furrows were detected by identifying locally deep (minima) points on the iris surface and reported as furrow length in millimetres. Iris volume was quantified. Associations between furrow length and dynamic changes in iris volume were assessed using linear regression model. With pupil dilation, furrow length increased (15.84 mm) whereas iris volume decreased (-1.19 ± 0.66 mm 3 ). Longer furrow length was associated with larger static iris volume, as well as smaller loss of iris volume with pupil dilation (β = -0.10, representing 0.1 mm 3 less loss in iris volume per 10 mm increase in iris furrow length; P = 0.002, adjusted for age, gender and changes in pupil size). Our iris furrow length measurements are robust and intuitive. Eyes with longer furrows have larger iris volume and lose less volume during physiological pupil dilation. These findings highlight the potential for iris surface features as indicators of iris morphological behavior. |
References: | Curr Opin Ophthalmol. 2011 Mar;22(2):96-101. (PMID: 21252671) Optom Vis Sci. 2012 Apr;89(4):483-8. (PMID: 22407252) Am J Hum Biol. 2011 Jul-Aug;23(4):567-9. (PMID: 21630365) Ophthalmology. 2014 May;121(5):1007-12. (PMID: 24405741) Br J Ophthalmol. 2012 Sep;96(9):1162-7. (PMID: 22653314) Ophthalmology. 2016 Oct;123(10 ):2077-84. (PMID: 27521171) Hong Kong Med J. 2001 Jun;7(2):118-23. (PMID: 11514744) Prog Brain Res. 2008;173:3-14. (PMID: 18929097) Ophthalmology. 2014 Nov;121(11):2081-90. (PMID: 24974815) J Glaucoma. 2003 Apr;12 (2):167-80. (PMID: 12671473) Am J Hum Genet. 2011 Aug 12;89(2):334-43. (PMID: 21835309) Am J Ophthalmol. 2009 Nov;148(5):657-669.e1. (PMID: 19878757) Br J Ophthalmol. 2016 Dec;100(12 ):1682-1685. (PMID: 26994112) Zhonghua Yan Ke Za Zhi. 2005 Jan;41(1):8-14. (PMID: 15774106) Ophthalmology. 2010 Jan;117(1):1-2. (PMID: 20114108) Mol Vis. 2004 Nov 02;10:821-31. (PMID: 15534585) Br J Ophthalmol. 2011 Jan;95(1):46-50. (PMID: 20530187) Invest Ophthalmol Vis Sci. 2013 Jan 23;54(1):708-13. (PMID: 23299474) Invest Ophthalmol Vis Sci. 2011 Nov 07;52(12):8672-9. (PMID: 21908580) Invest Ophthalmol Vis Sci. 2014 Oct 23;55(12):8144-8. (PMID: 25342619) Ophthalmology. 2015 Sep;122(9):1777-85. (PMID: 26299721) Ophthalmology. 2010 Jan;117(1):11-7. (PMID: 19815290) J Glaucoma. 2009 Mar;18(3):173-9. (PMID: 19295366) Ophthalmology. 2013 Dec;120(12):2517-24. (PMID: 23850092) Invest Ophthalmol Vis Sci. 2014 Mar 19;55(3):1672-83. (PMID: 24557354) Ophthalmology. 2010 Jan;117(1):3-10. (PMID: 19923002) |
تواريخ الأحداث: | Date Created: 20171222 Date Completed: 20190715 Latest Revision: 20190715 |
رمز التحديث: | 20240628 |
مُعرف محوري في PubMed: | PMC5738384 |
DOI: | 10.1038/s41598-017-18039-w |
PMID: | 29263345 |
قاعدة البيانات: | MEDLINE |
تدمد: | 2045-2322 |
---|---|
DOI: | 10.1038/s41598-017-18039-w |